Abstract: The present disclosure includes an endoprosthesis comprising a descending stent-graft, an ascending stent-graft, and/or a side-branch stent-graft. In various embodiments, an ascending stent-graft is capable of being coupled to a descending stent-graft, and/or a descending stent-graft can comprise a fenestration capable of being coupled to a side-branch stent-graft. In addition, in various embodiments, a descending and/or ascending stent-graft can comprise a reduced diameter portion that, when implanted within an aortic arch, recedes from a luminal surface of the aortic arch to allow a side-branch stent-graft to be maneuvered within the aortic arch.

Abstract: A stent graft (1) has a tubular body (3) defining a main lumen and a side tube (5) defining a side tube lumen and in fluid communication with the main lumen and defining a junction (13) between the tubular body and the side tube. The junction includes an acute angle of attachment (?). A first zig-zag stent (15) is wrapped around the tubular body such that a V portion of the first zig-zag stent is engaged about the acute angle of the junction and a second zig-zag stent (23) is wrapped around the side tube, such that a V portion of the second zig-zag stent is engaged about the acute angle of the junction, whereby the main lumen and the side tube are each kept open, independently, allowing fluid to flow freely therethrough.

Abstract: An endoluminal prosthesis that includes a support structure comprising a curvilinear portion having a first strut and a second strut that meet at an apex. Disposed on the support structure is an anchor with an anchor body and one or more barbs extending outwardly from the anchor body and where the anchor body comprises a multi-filar tube fits at least partially about, and conforms to the first strut, second strut, and the apex.

Abstract: The present disclosure relates to an endoluminal prosthesis, such as a stent graft that includes one or more fenestrations to accommodate endovascular disease, such as an aneurysm in cases where one or more side branches is involved. In one aspect, the prosthesis includes fenestrations that are pivotable to accommodate the dynamic geometry of the aortic branches.

Abstract: Vasculature closure devices, and systems and methods for their use, are provided. In one embodiment, the vasculature closure device includes an expandable support frame deployable within a vessel and a sealing membrane at least partially supported by the expandable support frame. Upon expanding the support frame, the vasculature closure device is configured to intraluminally position the sealing membrane against a puncture site existing in a vessel wall.

Abstract: The present disclosure relates to an endoluminal prosthesis, such as a stent graft that includes one or more fenestrations to accommodate endovascular disease, such as an aneurysm in cases where one or more side branches is involved. In one aspect, the prosthesis includes fenestrations that are pivotable to accommodate the dynamic geometry of the aortic branches. In another aspect, the pivotable fenestrations include a first perimeter, a band of flexible material attached and surrounding the first perimeter, a second perimeter attached to and surrounding the band of flexible material and a support frame disposed about a surface of the band of flexible material. The first perimeter, band of flexible material, and second perimeter have a geometric shape. The support frame includes a plurality of support units having curved segments. The curved segments of the support units may be concave with respect to an exterior surface of the prosthesis.

Abstract: A prosthesis having a tubular body of a biocompatible graft material having a proximal end, a distal end, a lumen therethrough, and a sidewall. The prosthesis includes at least one perfusion branch extending from the sidewall of the tubular body and having a proximal end, a distal end, and a lumen therethrough, where the lumen of the perfusion branch is in temporary fluid communication with the lumen of the tubular body. The perfusion branch comprises a self-sealing component, that after predetermined period of time precludes fluid flow out of the distal end of the perfusion branch.

Abstract: An endoluminal prosthesis system may include a main graft and an extension graft. The main graft may include a tubular main body having a sidewall, open proximal and distal ends, a lumen, and a fenestration in the sidewall. The extension graft may include a tubular extension body, and tubular first and second extension legs. Each of the first and second extension legs may extend from the extension body and include a lumen in fluid communication with the extension body lumen. The extension graft may be deployable within the main graft such that the extension body extends through the fenestration in the sidewall of the main body. Each of the first and second extension legs may extend outward away from the main graft. An auxiliary guide such as an auxiliary cannula and/or auxiliary guide wire may be preloaded in the extension graft and extend through the lumen of each of the second extension leg and the extension body.

Abstract: This invention relates generally to medical devices, and more particularly, to endovascular grafts and methods for treating branched vessels in diverse patient populations including those with shorter than average common iliac arteries. A bifurcated stent graft as described herein comprises adjacent facing fenestrations formed in the graft legs in order to permit proper placement of an “up-and-over sheath” and a side branch which may be proximally located in order to properly align the side branch with the opening of the branch vessel such as the internal iliac artery while keeping the graft bifurcation seated near the aortic bifurcation.

Abstract: An endoluminal prosthesis comprises a graft having a tubular body comprising proximal and distal ends, inner and outer surfaces, and partially and fully deployed states. A temporary channel is disposed external to the outer surface of the graft in the partially deployed state. The temporary channel begins at one of the proximal and distal ends of the graft, and extends along only a portion of a longitudinal length of the graft. The temporary channel is removed when the graft is in a fully deployed state.

Abstract: A medical device for insertion and expansion within a bifurcated lumen is described. An expansion region of the device has regions thereon which, in some cases, enable the device to fold into a predetermined configuration upon deflation. The regions may be defined by differing modulus of the device material.

Abstract: A system for treating a bifurcation includes first and second delivery catheters, each having an expandable member. A stent having a side hole is disposed on the second delivery catheter. A portion of the first delivery catheter is disposed under a portion of the stent. The first delivery catheter is slidable relative to the second delivery catheter, and the first delivery catheter passes through the side hole. Expansion of the first expandable member expands a proximal portion of the stent in a main branch vessel, and expansion of the second expandable member expands a distal portion of the stent in a side branch vessel.

Abstract: A stent-graft includes a short tube graft and patch located inside of a primary graft. The patch forms a smooth and reliably sealed transition between the primary graft and the short tube graft. Accordingly, the disruption to fluid, e.g., blood, flowing through the lumen of the primary graft by the short tube graft is minimal. Further, the patch supports the inner end of the short tube graft. Thus, the patch, the short tube graft and the primary graft form a stable three-dimensional structure.

Abstract: An implantable prosthetic for connection to a fluid flow pathway of a patient. The prosthetic is comprised of a primary tube structure which is in communication with a plurality of secondary tube structures each of which contains filters for trapping embolic particles, such as blood clots, air bubbles, thrombus. etc. within a fluid flow pathway within a patient. The prosthetic also contains a monitoring device to non-invasively the flow of fluids through a patient's fluid flow pathway.

Abstract: A bifurcated stent graft for animal or human implantation and method of delivery thereof. The device stent graft employs a first component having an axial passage communicating with the axial cavities of a second leg and longer first leg. A separate leg extension is engageable to the second leg. A first catheter engages the first component for translation to the implantation site and a second catheter engaged with the first is provided with a prepositioned guide wire inside the second leg which may be employed to easily position a guide wire for engagement of the second leg with the leg extension.

Abstract: A crimping method that crimps a stent over multiple catheters. The method includes differentially crimping a stent on certain portions of a balloon catheter so that a second catheter can be threaded through the uncrimped portion of the stent and exit through the links of a conventional stent design or through a specific hole in the stent designed for a branched vessel.

Abstract: Universal endovascular grafts are provided for evaluation and repair of damaged or aneurismal blood vessels. More particularly, the present invention relates to universal fenestrated and universal branched endografts for repair of blood vessels with branches, methods for implanting the endografts in the vessel and for making connection with one or more branches. The universal fenestrated endografts have a body with a first end, a second end, a first wall, a second wall, and an interior passage or lumen. The body further includes openings in communication with the passage at the first and second ends and one or more lateral fenestrations in communication with the lumen. The body further has a necked portion between the ends and a cannulation member. The universal branched endografts have a tubular body with a main lumen and four branch lumens. A large branch extends from the body. The four lumens are positioned about a circumference of the tubular body.

Abstract: An apparatus for repairing an aneurysm comprises a device having an inner graft tube and an inflatable outer balloon attached to an outer surface of the inner graft tube, and an inflatable deployment balloon. The inner graft tube is expandable within an artery to form a seal with the arterial wall above and/or below an aneurysm. The outer balloon is inflatable within the aneurysm with a rapidly settable substance to fill the aneurysm and support the device. The deployment balloon has an uninflated condition to fit within the inner graft tube and is inflatable within the inner graft tube to expand the inner graft tube within the artery and to maintain the inner graft tube expanded within the artery during inflation of the outer balloon.

Abstract: A bridging device for supporting occlusive masses within an aneurysm located at a vascular bifurcation.

Abstract: The present invention provides apparatus and methods for a conduit, such as an implantable conduit for a vessel. The conduit may comprise a main member and a side-branch member. The conduit may be implanted with the side-branch member initially disposed within the main member. When positioned, the side-branch member may then be extended from within the main member and into a vessel side-branch. The materials for the conduit may include circumferentially distensible and/or low recoil materials. The materials for the conduit may be constructed by various techniques and may include materials with enhanced flexibility and kink resistance.

Abstract: An endograft for a vessel having a vascular branch extending from the vessel is provided. The endograft includes a main body having a wall separating interior and exterior surfaces and adapted to be inserted within the vessel. The main body is characterized by a single proximal opening and two distal openings and at least one aperture extending through the wall. At least one stent is secured to the main body that upon expansion pressure fits the main body into the vessel. An open tunnel is secured to the interior surface of the main body around the main body aperture and secured somewhere along the tunnel length to provide fluid communication between the interior and exterior surfaces of the main body through the aperture and with the vascular branch in proximity to the main body aperture. The tunnel is readily formed independent of an expandable stent.

Abstract: A system for treating a bifurcation includes a first radially expandable stent and a second radially expandable stent. The first stent has a side hole and a plurality of lateral elements extending from the side hole. The second stent has a plurality of axial elements extending away from the proximal end of the second stent. The axial elements of the second stent interdigitate with the lateral elements of the first stent when both stents have been expanded.

Abstract: A catheter system and method are described for stenting a vessel at a bifurcation or sidebranch of the vessel. The catheter system includes a first balloon catheter, a second balloon catheter and a releasable linking device for holding the first and second balloon catheters arranged in a side-by-side configuration and aligned with one another along a longitudinal axis. The linking device allows the catheter system to be advanced as a unit and helps prevent premature or inadvertent dislodgement of the stent from the catheters, yet is releasable so that one or both of the balloon catheters can be released from the linking device and maneuvered separately from the rest of the catheter system when desired. The method utilizes the described catheter system for stenting bifurcated vessels using a modified “kissing balloons” technique.

Abstract: A prosthesis is disclosed for placement at an Os opening from a main body lumen to a branch body lumen. The prosthesis includes a radially expansible support at one end, a circumferentially extending link at the other end and at least one frond extending axially therebetween. The support is configured to be deployed in the branch body lumen, with the circumferentially extending link in the main lumen and the frond extendable across the Os.

Abstract: A balloon-expandable shunt is disclosed for shunting a vessel which has a graft with two ends and is coupled with or to at least one expandable support element at or near at least one of its ends. The shunt is bifurcated at an aperture that leads to a side-channel and which has a closed configuration and an open configuration such that when the aperture is in the closed configuration it defines a clot-resistant inner graft surface and when the aperture is in the open configuration it is configured to provide access to the shunt for a balloon that actuates the expandable support element. A balloon configured for actuating the shunt is also disclosed. A kit is also disclosed, which has a bifurcated graft that has at least one expandable support element and a balloon for actuating the at least one expandable support element.

Abstract: An endoprosthetic device for treating abdominal aortic aneurysms using suprarenal fixation. A stent ring is anchored in an area above the renal arties using self-flaring barbs that project during the nitinol expansion process. Sutures extend from the stent ring to an area below the renal arties to a bifurcated trunk portion comprising a nitinol fabric on a non-kinking frame. The bifurcated trunk is sealed proximal the iliac arteries and includes iliac leg holders having self-flaring retention struts for non-traumatic holding of iliac leg prosthetics. Suprarenal fixation and collapsible cells having retention projections and barbs that only flare during the nitinol expansion process assist in lowering the devices profile and sheathability for percutaneous delivery and may provide for recapturing the anchored device.

Abstract: A system for treating a bifurcation includes first and second delivery catheters, each having an expandable member. A stent having a side hole is disposed on the second delivery catheter. A portion of the first delivery catheter is disposed under a portion of the stent. The first delivery catheter is slidable relative to the second delivery catheter, and the first delivery catheter passes through the side hole. Expansion of the first expandable member expands a portion of the stent and expansion of the second expandable member expands the rest of the stent.

Abstract: A deployment apparatus and method for deploying one or more stents to a bifurcated vessel is provided. The invention is particularly suited for T-type bifurcated vessels where a side branch extends from a main branch. The deployment apparatus has a primary inflatable portion for engagement within the main branch and a secondary inflatable portion for engagement within the side branch. A main stent is arranged on the primary inflatable portion and radially expanded within the main branch while the secondary inflatable portion maintains registration with the side branch. A side branch stent is then arranged on the secondary inflatable portion and expanded within the side branch while the primary inflatable portion maintains registration with the expanded main stent. A bifurcated stent system suitable for bifurcated lesions is also provided comprising a side branch stent with a shaped end designed to engage a similarly shaped side opening in a main stent.

Abstract: A method is described for delivering a prosthesis to a branch region of a blood vessel, the branch region having first and second blood vessel branches, the prosthesis comprising a main conduit and first and second branch conduits. The method includes inserting a first guide wire in the blood vessel such that it extends through the blood vessel into the first blood vessel branch; inserting a second guide wire in the blood vessel such that it extends through the blood vessel into the second blood vessel branch; moving the prosthesis to the branch region by moving the first branch conduit along the first guide wire and the second branch conduit along the second guide wire; and moving the first/second branch conduit along the first/second guide wire from a first position in which they project inside the main conduit to a second position in which they project out from the main conduit.

Abstract: A method of deploying a stent in a bifurcation includes introducing two guidewires through the main vessel and using the two guidewires for guiding a dual lumen catheter carrying a stent first to an initial position proximal to the stent deployment position, retracting one wire, and projecting it from the catheter and through a side of the stent a branch guidewire into the second branch vessel, and then moving the catheter to the predetermined deployment position while guided by the main guidewire in the first branch vessel, and the branch guidewire in the second branch vessel. The stent is then expanded, and the catheter is removed with the stent remaining in its deployed position An alternative embodiment includes introducing one wire, advancing the system over the one wire and subsequently introducing the second wire.

Abstract: Shunt devices and a method for continuously decompressing elevated intraocular pressure in eyes affected by glaucoma by diverting excess aqueous humor from the anterior chamber of the eye into Schlemm's canal where post-operative patency can be maintained with an indwelling shunt device which surgically connects the canal with the anterior chamber. The shunt devices provide uni- or bi-directional flow of aqueous humor into Schlemm's canal.

Abstract: An apparatus for treatment of a bifurcation of a body lumen, the bifurcation having a main vessel and a branch vessel, the apparatus includes a bifurcated balloon with a first branch portion and a second branch portion, the second branch portion including an inflatable portion adapted to extend toward the branch vessel, the bifurcated balloon also having a proximal shaft portion and a distal shaft portion connected to the inflatable portion of the second branch portion, and wherein the first branch portion and the second branch portion each have a longitudinal axis, the axis of the first branch portion being substantially parallel to the longitudinal axis of the second branch portion.

Abstract: The present invention is directed to an intraluminal guiding device having an expandable guiding member so as to facilitate and overcome the difficulties associated with obtaining contra-lateral leg access of a bifurcated stent or a bifurcated stent graft with a second guidewire and a method for treating abdominal aortic aneurysms with such a device. The guiding device comprises a pre-loaded second wire positioned within the contra-lateral leg which facilitates access to said leg in accordance with the present invention.

Abstract: A catheter assembly may include a main balloon arranged to reside within the main vessel, and a branch balloon configured to extend from the main vessel into the branch vessel. A stent may be situated around the main balloon and may include a branch aperture at a location between proximal and distal open ends of the stent. The branch balloon may extend from within the stent, through the branch aperture, and into the branch vessel. The branch balloon, when inflated, may extend into the branch vessel. The main balloon, when inflated, may also expand the stent within the main vessel. In some arrangements, the branch balloon, when inflated, can function as an anchor within the branch vessel that resists radial and axial movement of the stent relative to the branch vessel and main vessel during expansion of the stent by the main balloon.

Abstract: An endovascular prosthetic system comprising an prosthetic device with a major lumen extending therethrough, a major wall, at least one opening in the major wall; at least one branch extending into the major lumen of the prosthetic device having a minor lumen, a minor wall, and a fenestration in the minor wall in communication with the major lumen; and at least one guide wire extending through the fenestration and out of the prosthesis through the opening.

Abstract: A connector for joining first and second hollow structures, comprising a fluid-constraining tube having a fluid-constraining neck extending therefrom, wherein the tube and the neck each comprise a lumen having first and second openings, the neck being joined to the tube such that fluid entering the first opening of the tube can exit the second opening of the tube, and fluid entering the first opening of the neck can exit the second opening of the tube; at least the portions of the tube adjacent to the first and second openings of the tube being biased radially outwardly so that they normally assume a radially-expanded configuration, but being capable of being restrained in a radially-contracted configuration, wherein the tube is sized so that, when it is in its radially-expanded configuration, it has an outer diameter which is larger than the inner diameter of the second hollow structure.

Abstract: A stent for use in a medical procedure having opposing sets of curved apices, where the curved section of one set of apices has a radius of curvature that is greater than the curved section of the other set of apices. One or more such stents may be attached to a graft material for use in endovascular treatment of, for example, aneurysm, thoracic dissection, or other body vessel condition.

Abstract: A vascular endoprosthesis (1) is disclosed which is capable of being arranged internally to the aortic arch (O), comprising: a tubular main body (2), to be housed in the internal lumen of the aortic arch (O); three tubular secondary bodies (3, 4, 5), originating from the main body (2) and to be housed in the right carotid artery (R), in the left carotid artery (L) and in the subclavian artery (S); and stent-type engagement means (10, 11, 13, 14, 15), intended to hold a longitudinal end portion (21, 22, 31, 41, 51) of the main and secondary bodies onto the internal wall of the respective vessel (FIG. 5).

Abstract: An aortic arch double-barreled main body stent graft and methods for its use, where the stent graft comprises, a main body stent graft having distal and proximal ends, the main body stent graft's length ranges from about 50-70 mm and the diameter at the proximal end ranges from about 40-60 mm, first and second lumens defined at the distal end of the main body stent graft, the first lumen's diameter ranges from about 18-30 mm, the second lumen's diameter ranges from about 18-30 mm, the first lumen is secured to the second lumen along a shared length, the shared length of the first and second lumens ranges from about 30-65 mm, and the main body stent graft defines a tubular wall that is contiguous with the first lumen and the second lumen such that any fluid entering the main body must exit through one of the first or second lumens.

Abstract: The present invention relates to devices and methods for the treatment of diseases in the vasculature, and more specifically, devices and methods for treatment of aneurysms found in blood vessels. In a first embodiment of the present invention, a two part prostheses, where one part is an expandable sponge structure and the other part is an expandable tubular mesh structure, is provided. In the first embodiment, the expandable sponge structure is intended to fill the aneurysm cavity to prevent further dilatation of the vessel wall by creating a buffer or barrier between the pressurized pulsating blood flow and the thinning vessel wall. In the first embodiment, the expandable tubular mesh structure is placed across the aneurysm, contacting the inner wall of healthy vessel proximal and distal to the aneurysm.

Abstract: A woven textile vascular prosthesis including a tubular trunk and at least one fork, each fork having an apex located between outgoing tubular branches with a small diameter, wherein at least a portion of a wall of the prosthesis in a zone of the apex is woven more densely than in other zones having an original weave construction.

Abstract: An endoluminal prosthesis may include a tubular body of a biocompatible graft material having proximal and distal ends and anterior and posterior sides. The prosthesis may include at least a first and a second fenestration. The first and second fenestrations may be spaced from one another circumferentially around the tubular body. The prosthesis may include at least one first diameter reducing tie positioned circumferentially on the posterior side of the prosthesis and engaging at least a circumferential segment of the posterior side to restrain the engaged segment from expansion. The prosthesis may include at least one second diameter reducing tie positioned circumferentially between the first and second fenestrations on the anterior side of the prosthesis and engaging at least a circumferential segment of the anterior side to restrain the engaged segment from expansion.

Abstract: An aortic stent includes a main tube including a main section having an outer diameter about equal to an inner diameter of a blood vessel of a descending aorta, and first and second tube bifurcations branched from the main section wherein the first tube bifurcation includes a first membrane for dividing inside of the first tube bifurcation into first and second spaces, and the second tube bifurcation includes a second membrane for dividing inside of the second tube bifurcation into third and fourth spaces; and at least one tube branch retained in the first, second, third or fourth space so that each tube branch has one end retained in the main tube and the other end in fluid communication with artery.

Abstract: An endoprosthetic device for treating abdominal aortic aneurysms using suprarenal fixation. A stent ring is anchored in an area above the renal arties using self-flaring barbs that project during the nitinol expansion process. Sutures extend from the stent ring to an area below the renal arties to a bifurcated trunk portion comprising a nitinol fabric on a non-kinking frame. The bifurcated trunk is sealed proximal the iliac arteries and includes iliac leg holders having self-flaring retention struts for non-traumatic holding of iliac leg prosthetics. Suprarenal fixation and collapsible cells having retention projections and barbs that only flare during the nitinol expansion process assist in lowering the devices profile and sheathability for percutaneous delivery and may provide for recapturing the anchored device.

Abstract: The present invention provides docking heads to be mounted on a graft so as to establish a vascular device that is coupled to a blood vessel with aneurysm, and dedicated delivery devices as well as methods of coupling. The vascular device comprises a graft having docking head at the proximal portion and another docking head at its distal portion, or two docking heads if the graft is bifurcated. The docking heads comprises a hollow truncated cone having a passage adapted to correspond the outer diameter of the graft and is provided with a plurality of outwardly pointing and inclined barbs. The vascular device is coupled to the blood vessel on both sides of the aneurysm while the docking heads act as guiding, anchoring and sealing means in a suture-less and rapid manner. The vascular device is modular and can be prepared according to the condition of the aneurysm and the dimensions of the blood vessels during operation.

Abstract: A stent graft includes at least one aperture extending through the main body thereof, into which an extension portion may be deployed for positioning within an adjacent branch flow lumen. The extension portions include self biasing features, wherein the extension is biased into engagement with the main body to seal the interface thereof. Additionally, the extension portion may be configured for tortuous or deviated anatomy, to enable sealing of the extension portion with the body while extending the extension portion in a substantially non-radial direction from the main body.

Abstract: An intraluminal device may be used at a bifurcation to anchor in an afferent vessel, allow perfusion to efferent vessels, and act as scaffolding to inhibit herniation of objects out of a neck of a bifurcation aneurysm. An intraluminal device may include a first side; a second side opposite the first side across a longitudinal axis of the intraluminal device; a proximal section configured to anchor in an afferent vessel; a distal section comprising a first wing and a second wing wherein, in an expanded state, the first wing extends from the first side to the second side and the second wing extends from the second side, through an opening of the first wing, and to the first side.

Abstract: The present invention provides, in a first aspect a bifurcated stent for use in juxtaposition with an angelogical bifurcation. The bifurcated stent comprises a proximal portion adapted to be disposed within a blood vessel in juxtaposition with a bifurcation, a first distal stent portion adapted to extend across the bifurcation into one of the branched blood vessels, and a second distal stent portion adapted to allow blood to flow from the proximal portion into the other branch blood vessel. The invention also embraces a bifurcated prosthesis including such a bifurcated stent and a tubular graft layer formed from a biocompatible fabric in juxtaposition with the stent. In a second aspect of the invention there is provided a stent connection for joining two stents one to the other to define a continuous lumen through the two stents. Said stent connection comprises a first stent including a male engaging portion which can be compressed radially inwardly and a second stent including a female cooperating portion.

Abstract: A stent delivery system and a method for implanting a stent are provided. The system includes first and second elongate shafts, each shaft including a proximal portion, a distal portion, and a lumen extending at least partially therethrough. The second shaft is longitudinally movable relative to the first shaft. The system also includes a bifurcated stent having a first arm positioned on the first shaft and a second arm positioned on the elongate shaft and a main body positioned on the first and second shafts. Proximal and first and second distal constraining members are releasably connected to the stent. The proximal and the first and second distal constraining members cooperatively apply longitudinal tensile force to at least a portion of the stent with the proximal and first and second distal constraining members each in the first position.

Abstract: A multiple-component expandable endoluminal system for treating a lesion at a bifurcation including a self expandable tubular root member having a side-looking engagement aperture, a self expandable tubular trunk member comprising a substantially blood impervious polymeric liner secured therealong; both having a radially compressed state adapted for percutaneous intraluminal delivery and a radially expanded state adapted for endoluminal support.