Abstract: The invention relates to a device for producing a spacer having a stem mold (1) which has an inner space (2), wherein the inner space (2) is accessible via a proximal opening (3) and wherein the stem mold (1) has a proximal wall (4) which peripherally delimits the proximal opening (3) of the stem mold (1), a head mold (5) which has in the interior thereof a hollow space (6), wherein the hollow space (6) has a spherical surface-shaped inner surface (7) and is accessible via a distal opening (8), wherein the head mold (5) has a distal wall (9) which peripherally delimits the distal opening (8) of the head mold (5), a metal core (10) which has a stem part (12), a head part (14) and a flange (16), wherein the flange (16) projects out from the metal core (10), is arranged between the stem part (12) and the head part (14) and has a proximal surface (18) and a distal surface (20), wherein the stem mold (1) and the stem part (12) are shaped such that the stem part (12) is arranged in the inner space (2), when the

Abstract: Disclosed is a wedge for use during a reverse shoulder arthroplasty. The wedge can comprise a body having a proximal surface and a distal surface. The proximal surface and the distal surface can each extend from a distal end of the body to a proximal end of the body. The distal end can have a distal length and the proximal end can have a proximal length. The distal length can be shorter than the proximal length. The proximal surface can have a proximal curvature and the distal surface can have a distal curvature. The proximal curvature or the distal curvature can approximate a curvature of a deltoid muscle.

Abstract: A bone anchor assembly comprising a shank, receiver, pressure insert, sleeve and closure. The sleeve having a body constructed of deformable material and including a transfer of non deformable material molded into the body of the sleeve to transfer force around the body. The receiver having interior guides and the insert having guide followers that cooperate to align the insert in the receiver and prevent rotation of the insert in the receiver.

Abstract: The present invention comprises devices, systems, and methods for elongating bone using an extension implant having a first end and a second end. The first end of the extension implant is inserted into an opening in the live bone and the second end of the extension implant is combined with an enlarged implant. A plurality of channels extend through the components to serve as conduits for delivering fluids and physiological signals which induce bone formation. Some embodiments include a subcutaneous cage assembly for helping to support the implant as the bone heals around it.

Abstract: A device for bridging a first amputated bone and a second amputated bone is described. The device comprises a first stem configured to be inserted into a cavity of the first amputated bone and a second stem configured to be inserted into a cavity of the second amputated bone. A first head is coupled to the first stem. The first head has a diameter greater than the diameter of the first stem. The first head has a flat surface configured to interface with a severed surface of the first amputated bone. A second head is coupled to the second stem. The second head has a diameter greater than the diameter of the second stem. The second head has a flat surface configured to interface with a severed surface of the second amputated bone. The device further comprises a bridging plate coupled to the first head and the second head.

Abstract: A bone void plug according to an exemplary aspect of the present disclosure includes, among other things, a plug body that extends along a longitudinal axis between a proximal face and a distal opening and a recessed opening that extends from the distal opening toward the proximal face, the recessed opening configured to receive a bone void filler.

Abstract: Embodiments of the invention include an implantable force distribution boot with hydraulic features that mimic the natural hydraulics of a joint. Further embodiments include an exterior prosthetic leg device having intermittent and/or variable electromagnetic features that can engage with magnetic blades on the implantable force distribution boot. In use, the exterior prosthetic leg can be maintained on a residual limb by magnetic force between the implanted blades and the exterior electromagnets. Also disclosed are surgical techniques for preparing a residual limb to better receive and adapt to a prosthetic device. The techniques include an improved surgical method for harvesting a vascularized glabrous skin free flap.

Abstract: The present invention comprises devices, systems, and methods for elongating bone using an extension implant having a first end and a second end. The first end of the extension implant is inserted into an opening in the live bone and the second end of the extension implant is combined with an enlarged implant. A plurality of channels extend through the components to serve as conduits for delivering fluids and physiological signals which induce bone formation. Some embodiments include a subcutaneous cage assembly for helping to support the implant as the bone heals around it.

Abstract: Implantable devices for the surgical treatment of bone, and particularly to a bone defect at a joint region, and even more particularly at the subchondral bone level of the joint region, are disclosed. The implantable devices may be formed of a bone material, and configured to serve the dual functions of providing mechanical strength and structural integrity to the area to be treated, while also facilitating the dispersal of a flowable material in the same area. Associated delivery tools are also provided.

Abstract: A delivery device for an osteochondral graft comprising a tube, a plunger and a graft retention assembly is disclosed. The tube has a bore having an inside diameter and extends from a proximal end to a distal end. The inside diameter of the bore is sufficient to accept an osteochondral graft of a desired diameter. The tube has a set of apertures located adjacent the distal end of the tube. The plunger is slidably disposed within the bore of the tube. The graft retention assembly comprises a collar and a set of tabs. The graft retention assembly is attached to the tube such that the tabs are disposed within the apertures of the tube. The tabs are biased towards each other but are capable of being displaced away from each other to receive or release the osteochondral graft.

Abstract: An implant for filling and/or distracting a body region, particularly a non-soft tissue cavity, has a plurality of segments wherein at least two of the segments are flexibly connected. The segments have a crush-strength sufficient to create and/or maintain the distraction of two or more non-soft tissue body surfaces, and to maintain the stability of the body region. The implant may be inserted into a cavity by an applicator having a cannula with a distal opening, and a rotary driver for applying force to move the implant within the cannula.

Abstract: A non-resorbable wound dressing can include a plug made from polytetrafluoroethylene (PTFE). The plug can have a three-dimensional shape. The plug can be substantially cylindrical. The PTFE can have a high density and be expanded. The PTFE can be non-porous or have a porosity of less than about 0.4 microns. The PTFE can also be unsintered and unexpanded. A method of regenerating alveolar bone includes placing a PTFE plug in a cavity formed in an alveolar bone. Placing the plug in the cavity can include contacting at least a portion of a peripheral surface of the plug with the gingival tissue surrounding the cavity. The method can also include inserting a bone graft material in the cavity before placing the plug in the cavity.

Abstract: The invention relates to an operation system comprising at least one implant and means for the fastening of the implant to a bone, wherein the fastening means include at least one solid spacer, which can be formed of hardened bone cement and is arranged between the implant and the bone in the implanted state, and hardenable liquid bone cement which can be introduced into hollow spaces or intermediate spaces present between the spacer and the implant and/or between the spacer and the bone and wherein the spacer, on the one hand, and the liquid bone cement, on the other hand, are provided with contrast agents chosen in dependence on an imaging observation process or inspection process, in particular an X-ray process, to be used in or after the operation such that the spacer and the liquid cement can be distinguished from the surroundings and from one another on the observation or inspection of their position, in particular in an X-ray.

Abstract: A system for securing a prosthesis in a bone includes a reference anchor for insertion into a cavity of a bone to define a reference point during prosthesis implantation, the reference anchor including a body having a mating feature and a gripping projection for engaging an inner surface of the bone cavity. The system also includes a stem having a terminal end adapted to mate with the engagement feature of the reference anchor such that the stem is disposed at a desired position relative to the reference point.

Abstract: A system for performing a minimally invasive surgical procedure includes a cannula, a surgical instrument for use through the cannula, and a remote positioning system to adjust the relative position between the surgical instrument and the cannula. By allowing a physician to perform the minimally invasive surgical procedure at a distance from the patient, the remote positioning system minimizes the radiation exposure of the physician while still providing accurate control over the procedure.

Abstract: A medical system (10) is provided having a pulling device (20) and an active substance chain (50). The active substance chain (50) has at least two storage units (51) arranged like a chain, and at least one of the storage units (51) is loaded with a medicinal active substance. The pulling device (20) has a grip element (30) and a coupling element (40), and the coupling element (40) has at least one recess (41, 41?). In a free position (100) the active substance chain (50) is arranged separated from the pulling device (20), while in an inserted position (110) at least one of the storage units (51) is arranged form-fitting in a recess (41, 41?). The active substance chain (50) can be moved reversibly from the free position (100) into the inserted position (110).

Abstract: A system for implanting a prosthetic device with an opening into a bone includes a plug that is removably received within the opening of the prosthetic device. The system also includes a bone removal tool that advances into the bone from outside the bone and that removes a portion of the bone while advancing into the bone to reveal the plug. The bone removal tool includes a plug engaging portion that engages with the plug. The bone removal tool at least partially removes the plug from the opening of the prosthetic device while engaged with the plug. Moreover, the system includes an alignment system that detects whether the bone removal tool and the plug are substantially axially aligned.

Abstract: Compositions for use in treating and repairing orthopedic defects are provided. The compositions are especially useful for performing percutaneous vertebroplasty, percutaneous kyphoplasty and other procedures. When cured, the compositions are relatively solid but compressible, and prior to curing are viscous liquids with a low enough viscosity to fill voids in cavities such as voids within fractured vertebrae. Optionally, the properties of a composition according to the invention can be adjusted taking into account the hardness and density of the orthopedic structure to be repaired. Also disclosed are devices and methods for using the compositions, and a kit containing components for forming and utilizing the composition.

Abstract: A bone cement collector includes a body having a structure that is permeable to bone cement and has opening for trapping bone cement. The body is releasably attached to an orthopaedic implant component at a location on the implant at which bone cement is likely to escape during positioning of the orthopaedic implant.

Abstract: A delivery device for an osteochondral graft comprising a tube, a plunger and a graft retention assembly is disclosed. The tube has a bore having an inside diameter and extends from a proximal end to a distal end. The inside diameter of the bore is sufficient to accept an osteochondral graft of a desired diameter. The tube has a set of apertures located adjacent the distal end of the tube. The plunger is slidably disposed within the bore of the tube. The graft retention assembly comprises a collar and a set of tabs. The graft retention assembly is attached to the tube such that the tabs are disposed within the apertures of the tube. The tabs are biased towards each other but are capable of being displaced away from each other to receive or release the osteochondral graft.

Abstract: A bone defect filler for implantation in a bone defect of a patient includes a particulate polymer distributed within a polymeric binder. The particulate polymer includes a plurality of particles, which may have substantially the same material composition as the polymeric binder. The particles of the particulate polymer may be formed in a variety of shapes and/or sizes to provide the bone defect filler with improved pore interconnectivity, material expansion and contamination characteristics, while maintaining sufficient mechanical strength and handling characteristics for bone repair applications. The bone defect filler also provides the flexibility to be molded or shaped in situ to fill the bone defect.

Abstract: The present invention extends to a stemmed amputation implant. In some embodiments, a dual stemmed implant includes a base plate and two intramedullary rods extending from the proximal side of the base plate. The two intramedullary rods are configured for insertion into corresponding intramedullary bone canals reamed into remaining portions of amputated bones, such as, for example, a tibia and fibula or an ulna and radius. The position of the intramedullary rods relative to one another is configured to maintain appropriate separation between amputated bones when the first intramedullary rod and the second intramedullary rod are inserted into the amputated bones. In some embodiments, a hollow tube replaces one or more of the intramedullary rods. A hollow tube can be configured to cover the exterior of a bone, such as, for example, the fibula, when the bone is not stable enough for intramedullary fixation.

Abstract: A bone cement collector includes a body having a structure that is permeable to bone cement and has opening for trapping bone cement. The body is releasably attached to an orthopaedic implant component at a location on the implant at which bone cement is likely to escape during positioning of the orthopaedic implant.

Abstract: A hip stem centralizer datum guide and method are provided for positioning a proximal portion of a hip stem component within bone cement in an intramedullary canal of a femur. The datum guide is positionable in a predetermined position relative to the intramedullary canal and is able to create a datum that records the predetermined hip stem component position relative to the intramedullary canal. The datum is able to be referenced to position the hip stem component in the predetermined hip stem component position in the bone cement in the intramedullary canal.

Abstract: A bone implant having a core section to which a prosthesis is eventually secured, and rib-like projections or anchoring prongs enhancing the hold of the implant in the bone. The invention is particularly, but not exclusively, intended as a dental implant. The socket for the implant is drilled in a bone using a suitable template which is subsequently inserted in an original pre-drilled bore and which serves as a guide for subsequent drilling of bores for the anchoring prongs or rib-like projections. Several different types of the templates are disclosed together with a number of compatible implants. A specific tool is also disclosed which reduces the damage to the bone by reducing the volume of the initial portion of the socket adapted to receive the associated template.

Abstract: A bone cement plug for fitting into the intramedullary canal within a bone to restrict flow of bone cement during surgery comprises a sleeve (2) whose wall is circumferentially continuous and has an outer surface (10) for contacting the wall (32) of the canal. The sleeve (2) is formed from a deformable material so that it can be expanded transversely to contact the surface (32) of the canal. The plug includes an expander which can be drawn through the cavity (12) in a direction generally along the axis of the sleeve (2), to cause the sleeve (2) to expand transversely to contact the surface (32) of the canal. The inner surfaces of the wall converge towards the end (16) of the sleeve (2) towards which the expander is drawn to cause the sleeve (2) to expand to contact the surface (32) of the canal.

Abstract: Described herein is a novel drug delivery assembly having particular applicability to the field of orthopedic and surgical medicine. The devices and assemblies described herein enable the efficient application and retention of potentially expensive therapeutic materials to very specific locations, particularly those associated with voids in bone and tissue. One particularly unique aspect of the present invention involves the introduction of constructs which promote the retention of therapeutic material in the target area of application for beneficial use, for example by forming a proximal barrier that prevents leakage of the therapeutic material out of the target area. Additionally, the present invention provides unique devices and methods for surgical introduction of such constructs.

Abstract: An implant for filling and/or distracting a body region, particularly a non-soft tissue cavity, has a plurality of segments wherein at least two of the segments are flexibly connected. The segments have a crush-strength sufficient to create and/or maintain the distraction of two or more non-soft tissue body surfaces, and to maintain the stability of the body region. The implant may be inserted into a cavity by an applicator having a cannula with a distal opening, and a rotary driver for applying force to move the implant within the cannula.

Abstract: A plug for filling a bone void, such as a void left behind after implant removal, and a method for using the same. The plug is strong and durable enough to increase the strength of the void and the bone surrounding the void upon insertion. The plug's porous, open-cell construction may increase the strength of the void and the bone surrounding the void by permitting bone growth into the plug. The plug may be provided with a channel configured to receive a bone growth promoting material, a medication, or another material.

Abstract: The present invention extends to a stemmed amputation implant. In some embodiments, a dual stemmed implant includes a base plate and two intramedullary rods extending from the proximal side of the base plate. The two intramedullary rods are configured for insertion into corresponding intramedullary bone canals reamed into remaining portions of amputated bones, such as, for example, a tibia and fibula or an ulna and radius. The position of the intramedullary rods relative to one another is configured to maintain appropriate separation between amputated bones when the first intramedullary rod and the second intramedullary rod are inserted into the amputated bones. In some embodiments, a hollow tube replaces one or more of the intramedullary rods. A hollow tube can be configured to cover the exterior of a bone, such as, for example, the fibula, when the bone is not stable enough for intramedullary fixation.

Abstract: A graft formation and delivery instrument comprising an outer barrel, a piston, and an inner pin. The outer barrel has a center aperture. The piston is seated within the center aperture, has a through bore, and is operable to move within the center aperture. The inner pin is seated within the through bore of the piston and operable to move within the through bore. The outer barrel receives multiple graft components that are contacted by at least one of the piston and the inner pin to assemble a composite graft from the graft components. The instrument is operable to direct the composite graft to a desired implant area and deposit the composite graft at the implant area.

Abstract: A method for forming a composite implant in a bone cavity is disclosed, which includes i) forming a first bone filler in a bone cavity; and ii) inserting a second bone filler into an unfilled space in the bone cavity, wherein the first bone filler has a higher compressive strength and slower bioresorption rate in comparison with the second bone filler.

Abstract: A tissue positioning device comprising a biocompatible member having a size and shape suitable for placement within a space adjacent to a tissue to be positioned and which acts to maintain the tissue in a desired position. The member may be a rigid or flexible spacer having a defined shape, or a bladder capable of receiving and being at least partially expanded by a filler material. The device can made from a variety of materials or a composite of materials as needed, and may include one or more attachment means by which it can be secured to nearby tissues such that it is maintained in a desired spatial location. The filler material can be any of a number of substances, including liquids, gases, a curable liquid such as bone cement or urethane foam, or a spring.

Abstract: A hip stem centralizer datum guide (40, 100, 200, 300) and method are provided for positioning a proximal portion of a hip stem component (44) within bone cement in an intramedullary canal of a femur. The datum guide is positionable in a predetermined position relative to the intramedullary canal and is able to create a datum (70, 72, 74, 76, 120, 220, 302) that records the predetermined hip stem component position relative to the intramedullary canal. The datum is able to be referenced to position the hip stem component in the predetermined hip stem component position in the bone cement in the intramedullary canal.

Abstract: A method for repairing defects in bones that may be used to remove a surface defect from the articulating surface of a bone. In one embodiment, a passage is formed in the bone and extending to an articulating surface of the bone, resulting in the removal of bone stock from the bone. By aligning the passage to intersect with the defect in the bone, the creation of the passage itself results in the removal of the defect from the articulating surface of the bone. A biocompatible material may then be inserted through the passage to replace the removed bone stock and may be formed to substantially replicate the shape of the articulating surface of the bone.

Abstract: An interbody fusion device in one embodiment includes a tapered body defining a hollow interior or chamber for receiving bone graft or bone substitute material. The body defines exterior threads which are interrupted over portions of the outer surface of the device. The fusion device includes truncated side walls so that on end view the body takes on a cylindrical form. In another embodiment, the tapered body is solid and formed of a porous biocompatible material having sufficient structural integrity to maintain the intradiscal space and normal curvature. The material is preferably a porous tantalum composite having fully interconnected pores to facilitate complete bone tissue ingrowth into the implant. In further embodiments, the fusion devices are provided with osteogenic material to facilitate bone ingrowth. A cap is also provided to block the opening of hollow fusion devices. The cap includes an occlusion body and an elongated anchor.

Abstract: Joint space interpositional prosthetic devices for positioning between surfaces of a joint in a patient are disclosed. The prosthetic device may have exterior surfaces affixed to the joint surfaces and may have internal surfaces which provide bearing surfaces. In an exemplary embodiment, the bearing surfaces are encapsulated within the device. The exterior surfaces of the device may include bone securement features to facilitate attachment of the prosthetic device to the joint surfaces.

Abstract: A system and method for joint restoration by extracapsular means includes an actuator operable to apply a force to a portion of a bone to effect a change 5 in the joint space geometry. One embodiment of the system includes an actuator operable to apply a cyclic loading to subchondral bone of a femur, wherein loads of a predetermined magnitude are alternately applied and released. Between periods of cyclic loading, rest periods are provided where no load is applied. Over time, the femoral joint surface is remodeled in accordance with the location, direction, magnitude, and frequency of the loading.

Abstract: The invention relates to an operation system comprising at least one implant and means for the fastening of the implant to a bone, wherein the fastening means include at least one solid spacer, which can be formed of hardened bone cement and is arranged between the implant and the bone in the implanted state, and hardenable liquid bone cement which can be introduced into hollow spaces or intermediate spaces present between the spacer and the implant and/or between the spacer and the bone and wherein the spacer, on the one hand, and the liquid bone cement, on the other hand, are provided with contrast agents chosen in dependence on an imaging observation process or inspection process, in particular an X-ray process, to be used in or after the operation such that the spacer and the liquid cement can be distinguished from the surroundings and from one another on the observation or inspection of their position, in particular in an X-ray.

Abstract: An expandable containment device is provided for use in containing a flowable material. The containment device includes an expandable housing extending along a longitudinal axis and defining an interior region, and including a first housing portion movably engaged with a second housing portion to allow expansion of the housing generally along the longitudinal axis to provide the housing with an axial dimension extending between adjacent bone structures. The containment device further includes an input port in fluid communication with the interior region of the housing and configured to deliver a flowable material into the interior region of the housing.

Abstract: A device for cement augmentation of bone implants that includes a hollow cylinder having an inner diameter, an outer diameter and a longitudinal axis. The hollow cylinder includes an inner cavity, a front end configured and adapted for insertion into a bone, a rear end having a bore hole in communication with the inner cavity, and a shell having at least one perforation. The device also includes a bone implant insertable into the hollow cylinder. The hollow cylinder is adapted and configured to receive unhardened bone cement through the bore hole into the inner cavity.

Abstract: A hip stem centralizer and method are provided for positioning a proximal portion of a femoral hip stem component at a desired radial position within an intramedullary canal of a femur. The hip stem centralizer includes a resilient opening that is elastically compressed upon receiving the hip stem to bias the hip stem to a desired position in the intramedullary canal.

Abstract: This invention relates to a cement, which comprises in its main phase of microcrystalline magnesium ammonium phosphate and nanoapatite after hardening and thus at the same time has considerable strength. The material is biologically degradable and is suitable for application in tooth cements, as bone replacement, as bone filler, as bone cement or as bone adhesive.

Abstract: The present invention provides a positioner for controlling the position of a femoral hip implant within the intramedullary canal of a femur.

Abstract: A transcutaneous prosthesis is disclosed comprising a first component (1) shaped for implantation into a bone (2), a second component (4) intended for location between the bone (2) and the skin, and a third component (5) intended for location exterior to the skin surface, having a low surface energy which deters bacterial adhesion. The second component (4) may carry an adhesion-promoting protein.

Abstract: A prosthesis (10) including a stem (12) for implantation at least partially within the medullary canal (14) of a long bone (16). The prosthesis (10) further includes a rod (20) operably associated with the stem (12) and a centralizer (22) having an opening (24) for receiving at least a portion of the rod (20). The centralizer (22) has a surface (26) for guiding the rod (20) into the opening (24).

Abstract: Apparatus and methods are disposed for maintaining the proper positioning of a prosthetic implant having proximal and distal ends within a prepared bone cavity during cement injection and curing. First stabilization means, implantable within the bone cavity, minimize lateral movement of the distal end of the implant, while second stabilization means, physically separate from the means for minimizing lateral movement of the distal end of the implant, minimize both the lateral movement of the proximal end of the implant and the rotational movement of the implant overall. In the preferred embodiment, the second stabilization means includes an apertured cap removably securable to the end of a bone having the prepared cavity through which the implant is inserted and held in place.

Abstract: A plug for insertion into a bone canal is disclosed. The plug comprises an elongate central body of substantially constant cross section carrying at least four radially extending flanges of substantially equal shape and size. The flanges form solid, disk-like structures, free of cuts and are axially spaced along the central axis of the body, such that they extend in substantially parallel planes. The plug is made of a copolymer of a polyalkylene glycol terephthalate and an aromatic polyester.

Abstract: A plug for insertion into a bone canal is disclosed. The plug comprises an elongate central body of substantially constant cross section carrying at least four radially extending flanges of substantially equal shape and size. The flanges form solid, disk-like structures, free of cuts and are axially spaced along the central axis of the body, such that they extend in substantially parallel planes. The plug is made of a copolymer of a polyalkylene glycol terephthalate and an aromatic polyester.

Abstract: The present invention provides a distal tip for the positioning of artificial joint stem that is capable of reliably guiding the insertion of the stem of the cementless artificial joint into a bone canal and positioning the distal end portion of the stem that is inserted into the bone canal at a planned position, thereby to maintain the entire stem in a favorable posture in the bone canal, and prevent osteolysis and loosening of the artificial join even when the distal tip is used.