Abstract: A method is described of improving adhesion of an ocular implant to corneal tissue by forming an implant adhesive layer on the ocular implant, the implant adhesive layer having greater adhesive strength than a rest of the implant or by forming a corneal adhesive layer on a posterior surface of a posterior portion of the corneal tissue, the corneal adhesive layer having greater adhesive strength than a rest of the corneal tissue.

Abstract: In certain embodiments, an ophthalmic lens includes an optic having an anterior surface, a posterior surface, and an optical axis. At least one of the anterior surface and the posterior surface includes a first zone extending from the optical axis to a first radial boundary and a second zone extending from the first radial boundary to the edge of the optic. The first zone includes an inner region and an outer region separated by a phase shift feature, the phase shift comprising a ridge extending outwardly from the inner region and the outer region.

Abstract: A multicomponent intraocular lens implantable in an optical system of a human eye, comprising: a base component and a front component, the front component comprising an attachment tab which extends from a circumferential side of the optical portion of the front component and engages the flange for attaching the front component to the base component, wherein the attachment tab of the front component comprises a resilient projection that protrudes away from the optical portion beyond the flange, wherein a portion of the resilient projection is located at a non-overlapping position with respect to the haptic of the base component in a circumferential direction around the optical portions, wherein the portion of the resilient projection has a back surface which is located backwards from a front surface of the haptic of the base component in the thickness direction of the base component.

Abstract: A intraocular lens system includes an artificial capsular bag adapted for implantation within a natural capsular bag of an eye and an intraocular lens adapted to be received within the artificial capsular bag. At least a portion of the intraocular lens tilts and moves forwards within the artificial capsular bag under gravitational force with respect to a cornea and retina of the eye to create myopia.

Abstract: An intraocular lens for providing enhanced vision includes an optic having a clear aperture having an outer diameter. The optic has opposing first and second surfaces disposed about an optical axis, the first surface including a cross-sectional profile. The optic further includes central and outer zones that fill the entire clear aperture of the optic. The central zone is disposed about the optical axis having an outer diameter, the profile in the vicinity of the central zone having a constant radius of curvature or a radius of curvature that increases with increasing radius from the optical axis.

Abstract: An ophthalmic lens with a circular surface structure and limited adjacent echelettes that provides enhanced image quality across an extended range of foci.

Abstract: The present invention relates to a posterior chamber intraocular lens (IOL), comprising: an optic consisting of an effective optical area and an effective optical area edge; at least two haptics connected to the optic, wherein a posterior surface of the effective optical area is a convex surface, and a basic spherical surface thereof has a radius of curvature in a range of 6.6 mm-80.0 mm.

Abstract: An ophthalmic lens is disclosed, one embodiment comprising an optic having an anterior surface and a posterior surface disposed about an optical axis, wherein at least one of the surfaces has a profile characterized by superposition of a base profile and an auxiliary profile, the auxiliary profile comprising a continuous pattern of surface deviations from the base profile. The auxiliary profile is a sinusoidal profile and can be amplitude modulated, frequency modulated or both amplitude and frequency modulated. The ophthalmic lens can be an IOL.

Abstract: An intraocular system is presented that may include an electro-active element having multiple independently controllable zones or pixels, and a controller capable of being remotely programmed. The system or element may be flexible, such that it can be folded for insertion into the eye. The system may include various energy storage and charging mechanisms to provide power to the lens and/or the controller.

Abstract: An accommodating intraocular lens implant includes an anterior floating lens unit, a posterior lens unit, an anterior lens link, a posterior lens link, and an anterior rim link, which comprises an anterior rim jointed element. An anterior rim complex is disposed such that the anterior floating lens unit is movable toward and away from the anterior rim complex, in an anterior-posterior direction. A lever is connected (a) at a first longitudinal site along the lever, to the anterior floating lens unit by the anterior lens link, (b) at a second longitudinal site along the lever, to the anterior rim complex by the anterior rim link, and (c) at a third longitudinal site along the lever, to the posterior lens unit by the posterior lens link. The second site is longitudinally between the first and the third sites along the lever, such that the second site serves as a fulcrum for the lever.

Abstract: An ophthalmic lens comprising a main lens part, a recessed part, an optical centre, and an optical axis through the optical centre, the main lens part having at least one boundary with the recessed part, the main lens part having an optical power of between about ?20 to about +35 dioptre, the recessed part positioned at a distance of less than 2 mm from the optical centre and including a near part having a relative dioptre of about +1.0 to about +5.0 with respect to the optical power of the main lens part, the boundary or boundaries of the recessed lens part with the main lens part form a blending part or blending parts, are shaped to refract light away from the optical axis, and have a curvature resulting in a loss of light, within a circle with a diameter of 4 mm around the optical centre, of less than about 15%.

Abstract: An apparatus, such as lenses, a system and a method for providing custom ocular aberrations that provide higher visual acuity. The apparatus, system and method include inducing rotationally symmetric aberrations along with an add power in one eye and inducing non-rotationally symmetric aberrations along with an add power in the other eye to provide improved visual acuity at an intermediate distance.

Abstract: An ophthalmic lens for providing enhanced or extended depth of focus includes an optic having an aperture disposed about an optical axis. The optic includes a first surface having a first shape and an opposing second surface having a second shape, the first and second surfaces providing, a base power and, in some embodiments an add power. The optic further includes an extended focus mask disposed upon at least one of the first shape and the second shape that is configured to provide the enhanced or extended depth of focus for one or more foci of the optic, as compared to a similar optic not having the extended focus mask.

Abstract: An intraocular lens for providing a subject with vision at various distances includes an optic having a first surface with a first shape, an opposing second surface with a second shape, a multifocal refractive profile, and one or more diffractive portions. The optic may include at least one multifocal diffractive profile. In some embodiments, multifocal diffractive and the multifocal refractive profiles are disposed on different, distinct, or non-overlapping portions or apertures of the optic. Alternatively, portions of the multifocal diffractive profiles and the multifocal refractive profiles may overlap within a common aperture or zone of the optic.

Abstract: A system/method allowing hydrophilicity alteration of a polymeric material (PM) is disclosed. The PM hydrophilicity alteration changes the PM characteristics by decreasing the PM refractive index, increasing the PM electrical conductivity, and increasing the PM weight. The system/method incorporates a laser radiation source that generates tightly focused laser pulses within a three-dimensional portion of the PM to affect these changes in PM properties. The system/method may be applied to the formation of customized intraocular lenses comprising material (PLM) wherein the lens created using the system/method is surgically positioned within the eye of the patient. The implanted lens refractive index may then be optionally altered in situ with laser pulses to change the optical properties of the implanted lens and thus achieve optimal corrected patient vision. This system/method permits numerous in situ modifications of an implanted lens as the patient's vision changes with age.

Abstract: The invention relates to an ophthalmic lens comprising a main lens part, a recessed part, an optical center, and an optical axis through said optical center, said main lens part having at least one boundary with said recessed part, said main lens part having an optical power of between about ?20 to about +35 dioptre, said recessed part positioned at a distance of less than 2 mm from said optical center and comprising a near part having a relative dioptre of about +1.0 to about +5.0 with respect to the optical power of said main lens part, said boundary or boundaries of said recessed lens part with said main lens part form a blending part or blending parts, are shaped to refract light away from said optical axis, and have a curvature resulting in a loss of light, within a circle with a diameter of 4 mm around said optical center, of less than about 15%.

Abstract: The invention relates to a haptic combination for accommodating an intraocular lens comprising at least one optical element (5) adapted to provide at least two optical functions including provision of a fixed optical power and provision of variable optical power, wherein the haptic combination comprises at least a first haptic (12) adapted to provide anchoring and positioning of at least one of the optical elements and at least a second haptic (7) adapted to provide transfer of movement from at least one driving means (8) in the eye to at least one of the optical elements, wherein movement of the second haptic is independent from movement of the first haptic. The invention also relates to an intraocular accommodating lens comprising the least one haptic combination of the kind referred to above.

Abstract: A diffractive multifocal design for ocular implant is provided. This ocular implant includes a diffractive multifocal intraocular lens (IOL) and a number of haptics. The diffractive multifocal IOL passes optical energy to distance, intermediate and near foci. The haptics mechanically couple to the diffractive multifocal IOL in order to position and secure the diffractive multifocal IOL within the eye. The diffractive multifocal IOL may include both a diffractive region and a refractive region, the diffractive multifocal IOL operable to phase shift optical energy such that constructive interference occurs within the diffractive region and the refractive region.

Abstract: An intraocular lens in which deterioration in contrast is suppressed even when the optical axis of the intraocular lens is decentered from the optical axis of the eyeball when the intraocular lens is inserted into the eye while the advantage of a conventional aberration reduction type intraocular lens that the image is seen clearly is sustained by employing such a power distribution as respectively having at least one positive power deviation region (E1) having a power larger than that represented by the reference power distribution and at least one negative power deviation region (E2) having a power smaller than that represented by the reference power distribution in the central region of the intraocular lens assuming that a power distribution being set to cancel the spherical aberration of cornea when the intraocular lens is inserted into the eye is the reference power distribution.

Abstract: Provided is an intraocular lens having a novel structure with high utility which is easy to adapt to patients, and can improve quality of vision (QOV). In an intraocular lens, an optical characteristic is set rotationally symmetric around an optical axis, and a spherical aberration of a size corresponding to a coma aberration remaining in a patient's eye after extraction of a human lens of the eye is set.

Abstract: An embodiment of the intraocular implant includes two portions, a single-focus or multi-focus optical central portion, and a haptic peripheral portion. The haptic peripheral portion is formed of two extensions extending diametrically with respect to the optical central portion, aimed at immobilizing the implant in the capsular bag by applying their end portions against the edges of the capsular bag, on the inner side thereof. The extensions forming the haptic portion each extend along a plane that is inclined with respect to the main plane of symmetry of the optic portion, and according to inclinations in opposite directions.

Abstract: An intraocular lens for providing accommodative vision to a subject includes a frame disposed about an optical axis, a first optical element, a second optical element, and a connecting element operably coupling the frame to the optical elements. The frame comprises an anterior frame element and a posterior frame element. The connecting element is configured to convert a first displacement between the frame elements in a direction that is substantially parallel to the optical axis into a second displacement between the optical elements that is substantially perpendicular to the optical axis. The second displacement may be translational and/or rotation. In some embodiments, the optical elements are two varifocal lenses.

Abstract: An intraocular lens provided for implantation into an eye, includes a lens body having a central region, haptics for holding the intraocular lens in place within the eye after implantation, and an activatable zone outside the central region. After implantation of the intraocular lens into the eye, the lens body is deformed in the central region and/or at least one of the position, the rotation or the tilt of the intraocular lens within the eye changes upon irradiating only the activatable zone with laser radiation.

Abstract: In one aspect, the present invention provides an ophthalmic lens (e.g., an IOL) that includes an optic having an anterior surface and a posterior surface disposed about an optical axis. At least one of the surfaces (e.g., the anterior surface) has a profile characterized by superposition of a base profile and an auxiliary profile. The auxiliary profile can include an inner region, an outer region and a transition region between the inner and the outer regions, where an optical path difference across the transition region (i.e., the optical path difference between the inner and the outer radial boundaries of the transition region) corresponds to a non-integer fraction (e.g., ½) of a design wavelength (e.g., a wavelength of about 550 nm).

Abstract: An intraocular lens for correcting or reducing the astigmatism of a cornea includes an optical element that has optical properties and characteristics that make it tolerant of rotational misalignment, when compared to a comparable lens having a uniform astigmatism orientation across its entire optical element, leading to more relaxed tolerances for a surgeon that implants the lens. The optical element of the toric ophthalmic lens has meridians associated therewith, including a high power meridian and a low power meridian orthogonal to the high power meridian. The optical element has at least one radially modulated meridian along which power monotonically varies with increasing radial position.

Abstract: In one aspect, the present invention provides a method for correcting vision that employs two lenses, at least one of which is a multifocal lens, with different focusing characteristics for use in the two eyes of the patient. The visual performance of each lens (e.g., visual contrast or acuity) is selected in accordance with a predefined relation so as to optimize the binocular visual performance provided by the combination of the lenses.

Abstract: The present invention relates to devices, systems, and methods for optimizing peripheral vision. In particular, methods are disclosed which include utilizing particular characteristics of the retina in optimizing peripheral vision. Additionally, various IOL designs, as well as IOL implantation locations, are disclosed which optimize peripheral vision.

Abstract: An intraocular lens has a polymeric optic defined by a harder posterior layer and a softer anterior layer. Haptics having a fulcrum attached to the posterior layer and a resistance arm attached to the anterior layer are provided. A bias is provided to the haptic to rotate the haptics about the fulcrum and cause the resistance arm to deform the softer anterior layer about the harder posterior layer to increase the optical power of the lens. As the haptic rotates, it axially displaces the optic anteriorly to additionally increase the optical power. The optical power is adjustable in response to stresses induced by the eye. The haptics are subject to a pre-bias that urges the haptics to rotate or bend about the fulcrum. Temporary restraints are provided to the haptics to retain a stressed shape of the lens against the bias during a post-implantation healing period.

Abstract: A multifocal intraocular lens providing greater or lesser refraction in relation to the position of the head and eyes of a user. The lens body is inserted into an artificial capsule bag or into a fluid-filled enucleated natural lens capsule of an eye, wherein the lens body encompasses the optical axis of the eye and by movement of the lens body within the capsule, provides different greater or lesser refraction depending upon the position of the eye.

Abstract: In one aspect, the present invention provides an ophthalmic lens (e.g., an IOL) that includes an optic having an anterior surface and a posterior surface disposed about an optical axis. At least one of the surfaces (e.g., the anterior surface) has a profile characterized by superposition of a base profile and an auxiliary profile. The auxiliary profile can include an inner region, an outer region and a transition region between the inner and the outer regions, where an optical path difference across the transition region (i.e., the optical path difference between the inner and the outer radial boundaries of the transition region) corresponds to a non-integer fraction (e.g., ½) of a design wavelength (e.g., a wavelength of about 550 nm).

Abstract: The invention relates to an intraocular lens (1) including an anterior surface (4) and a posterior surface (5) and having a substantially antero-posterior optical axis (6). In this lens, one of these anterior and posterior surfaces includes a first diffractive profile (9) forming at least one first diffractive focal point (11) of order +1 on said optical axis, and a second diffractive profile (10) forming a second diffractive focal point (12) of order +1 on said optical axis which is distinct from the first diffractive focal point of order +1. At least one portion of said second diffractive profile is superposed to at least one portion of the first diffractive profile.

Abstract: Methods and systems for obtaining an ocular aberration measurement of an eye of a patient are provided. Exemplary techniques involve obtaining a first induced metric for the eye that corresponds to a first accommodation state of the eye, obtaining a second induced metric for the eye that corresponds to a second accommodation state of the eye, and determining a natural metric of the eye based on the first and second induced metrics. An induced metric may include a pupil size or a spherical aberration. Techniques can also include determining a target metric for the eye base on the natural metric, determining whether an actual metric of the eye meets the target metric, obtaining an ocular aberration measurement of the eye if the actual metric meets the target metric, and determining a treatment for the eye based on the ocular aberration measurement.

Abstract: An adjustable multifocal intraocular lens system for an individual's eye, includes a base multifocal intraocular lens having an optic with an optical axis, a peripheral edge, a multifocal optical power anterior surface and a posterior surface along with an attachment for maintaining the base multifocal lens in the individual's eye with the optical axis centered along an eye optical axis. An enhanced multifocal intraocular lens is provided with an optic with a peripheral edge, an anterior surface and a reverse multifocal optical power posterior surface, and a coupling enables assembly of the base lens and enhance lens with the enhance lens posterior surface overlaying the base lens anterior surface in order that the enhance intraocular lens reverse multifocal surface adjust multifocal powers of the base IOL by substantially masking near power of the base multifocal intraocular lens.

Abstract: In accordance with the present invention, a multifocal intraocular lens provides greater or lesser refraction in relation to the position of the head and eyes of a user. A multifocal intraocular lens body for insertion into a fluid-filled enucleated natural lens capsule of an eye is provided wherein the lens body encompasses the optical axis of the eye and provides different greater or lesser refraction depending upon the position of the eye.

Abstract: An intraocular lens device that includes an intraocular lens optics that provides at least two powers of magnification one being near vision power and the other being distance vision power. The lens optics has surface modulations that are responsible for providing the near vision power. The zone structure provides an add power of over 6 diopters. The add power indicative of an extent that the near vision focusing power is greater than the distance vision focusing power.

Abstract: In one aspect, the present invention provides an ophthalmic lens (e.g., an IOL) that includes an optic having an anterior surface and a posterior surface disposed about an optical axis. At least one of the surfaces (e.g., the anterior surface) has a profile characterized by superposition of a base profile and an auxiliary profile. The auxiliary profile can include an inner region, an outer region and a transition region between the inner and the outer regions, where an optical path difference across the transition region (i.e., the optical path difference between the inner and the outer radial boundaries of the transition region) corresponds to a non-integer fraction (e.g., ½) of a design wavelength (e.g., a wavelength of about 550 nm).

Abstract: A radially segmented apodized diffractive multifocal IOL for ocular implant is provided. The ocular implant can comprise a radially segmented apodized diffractive multifocal intraocular lens optic and a number of haptics. The radially segmented apodized diffractive multifocal IOL may pass optical energy in both photopic and mesopic conditions. The radially segmented apodized diffractive multifocal IOL includes a number of radially segmented apodization zones, each radially segmented apodization zones having a unique focal length. The haptics mechanically couple to the apodized diffractive multifocal IOL optic in order to position and secure the apodized diffractive multifocal IOL within the eye. The radially segmented apodized diffractive multifocal IOL may include both a diffractive region and a refractive region.

Abstract: A multifocal lens device is disclosed. The device comprises a lens body being formed with a plurality of concentric annular zones separated by slanted steps. The concentric zones effect both diffraction and refraction of incident light, while the steps are substantially devoid of any diffractive or refractive power.

Abstract: An apparatus, system and method including an ophthalmic lens having an optic with an anterior surface, a posterior surface, and an optical axis. The ophthalmic lens further includes a first region having a first optical power and a second region having a second optical power. The ophthalmic lens further includes a third region having an optical power that progresses from the first optical power to the second optical power. The progression may be uniform or non-uniform. Each of the first, second and progression optical power may include a base power and an optical add power. Each of the first, second and progression regions may provide a first focus, a second focus and a plurality of third foci, respectively.

Abstract: The invention relates to an ophthalmic lens comprising a main lens part, a recessed part, an optical centre, and an optical axis through said optical centre, said main lens part having at least one boundary with said recessed part, said main lens part having an optical power of between about ?20 to about +35 dioptre, said recessed part positioned at a distance of less than 2 mm from said optical centre and comprising a near part having a relative dioptre of about +1.0 to about +5.0 with respect to the optical power of said main lens part, said boundary or boundaries of said recessed lens part with said main lens part form a blending part or blending parts, are shaped to refract light away from said optical axis, and have a curvature resulting in a loss of light, within a circle with a diameter of 4 mm around said optical centre, of less than about 15%.

Abstract: An accommodating intraocular lens, for use in an eye, is made from flexible, optionally elastic, bio-compatible lens body material surrounding a closed and sealed lens cavity which is filled with bio-compatible optical liquid, optionally a gel. The optical liquid has a refractive index sufficiently high to, in cooperation with the ciliary muscle, focus light, incident on the eye, on the retina, and to provide accommodation. The curvature of the front surface of the lens is deformable, by the pressure expressed by the ciliary body during the accommodative effort, thus to change the radius of curvature of the anterior body member and/or the posterior body member, thus providing smooth focusing, including from far distance in the relaxed state to near distance of less than 50 centimeters in the accommodative state.

Abstract: The invention relates to novel intraocular lenses. The lenses are capable of post-operative adjustment of their optical properties, including conversion from single focal lenses to multifocal lenses.

Abstract: An ophthalmic lens is presented in which the lens includes a progressive addition region and a dynamic optic. The dynamic optic and the progressive addition region are in optical communication. The progressive addition region has an add power which is less than a user's near viewing distance add power. The dynamic optic, when activated, provides the additional needed optical power for the wearer to see clearly at a near distance. This combination leads to the unexpected result that not only does the wearer have the ability to see clearly at intermediate and near distances, but the level of unwanted astigmatism, distortion, and vision compromise are reduced significantly.

Abstract: A method, system and apparatus for vision correction are disclosed. The method, system and apparatus include a toric intraocular element for correcting astigmatism and having a cylinder power, and a depth of focus extender coupled to the toric intraocular element, the depth of focus extender extending a depth of focus. The extended depth of focus may reduce sensitivity of the toric intraocular element to at least one of rotation and selected cylinder power.

Abstract: An adjustable multifocal intraocular lens system for an individual's eye, includes a base multifocal intraocular lens having an optic with an optical axis, a peripheral edge, a multifocal optical power anterior surface and a posterior surface along with an attachment for maintaining said base multifocal lens in the individual's eye with the optical axis centered along an eye optical axis. An enhanced multifocal intraocular lens is provided with an optic with a peripheral edge, an anterior surface and a reverse multifocal optical power posterior surface, and a coupling enables assembly of the base lens and enhance lens with the enhance lens posterior surface overlaying the base lens anterior surface in order that the enhance intraocular lens reverse multifocal surface adjust multifocal powers of the base IOL by substantially masking near power of the base multifocal intraocular lens.

Abstract: An intraocular lens for providing vision to an animal or human subject has anterior and posterior sides. The lens includes an optic body, one or more haptics, and one or more marks. Each mark has four or more features disposed along an imaginary line when viewed from the anterior side and/or the posterior side. The mark(s) may be used as an aid in angularly aligning the lens during use.

Abstract: A diffractive multifocal design for ocular implant is provided. This ocular implant includes a diffractive multifocal intraocular lens (IOL) and a number of haptics. The diffractive multifocal IOL passes optical energy to distance, intermediate and near foci. The haptics mechanically couple to the diffractive multifocal IOL in order to position and secure the diffractive multifocal IOL within the eye. The diffractive multifocal IOL may include both a diffractive region and a refractive region, the diffractive multifocal IOL operable to phase shift optical energy such that constructive interference occurs within the diffractive region and the refractive region.

Abstract: The invention relates to a lens that can be implanted in the cornea for correcting vision defects, such as presbyopia. It consists of a zonal diffractive lens with phase inversion that comprises an alternation of optically active or “full” annular areas (2) and of optically inactive or empty annular areas (3) which are all concentric. The empty annular areas (3) are filled with an optically inactive “cement” that binds together the “full” annular areas (2) in order to ensure the stability thereof. The cement is a hydrogel pervious to nutrients and oxygen having an optical index close to that of the cornea.

Abstract: Intraocular implants and methods of making intraocular implants are provided. The intraocular implants can improve the vision of a patient, such as by increasing the depth of focus of an eye of a patient. In particular, the intraocular implants can include a mask having an annular portion with a relatively low visible light transmission surrounding a relatively high transmission central portion such as a clear lens or aperture. This construct is adapted to provide an annular mask with a small aperture for light to pass through to the retina to increase depth of focus. The intraocular implant may have an optical power for refractive correction. The intraocular implant may be implanted in any location along the optical pathway in the eye, e.g., as an implant in the anterior or posterior chamber.

Abstract: Aspects of the present invention provide multifocal lenses having one or more multifocal inserts comprising one or more diffractive regions. A diffractive region of a multifocal insert of the present invention can provide a constant optical power or can provide a progression of optical power, or any combination thereof. A multifocal insert of the present invention can be fabricated from any type of material and can be inserted into any type of bulk lens material. A diffractive region of a multifocal insert of the present invention can be positioned to be in optical communication with one or more optical regions of a host lens to provide a combined desired optical power in one or more vision zones. Index matching layers of the present invention can be used to reduce reflection losses at interfaces of the host lens and multifocal insert.