Abstract: A test system for measuring the concentration of an analyte in a biological fluid sample comprises: a plurality of test members (16) in a container (10), each test member (16) including reagent means for indicating the catalytic activity of an enzyme when in the presence of a biological fluid containing an analyte acted upon by the enzyme; 0 a test meter (2) for receiving a test member (16), the meter (2) having circuitry for performing a measurement on a test member received therein to produce a measured physical value, means for determining an analyte concentration value for a specified biological fluid from said measured physical value, and means (4) for indicating a determined analyte concentration value; a Container RFID tag (14) associated with the container (10) which includes data specific to said plurality of test members (16); and a Patient RFID tag (28) which includes data specific to a patient; and wherein said test meter (2) includes means for reading and storing data from said Container RFID tag

Abstract: A system allows for the safe, rapid, efficient recovery of a drug solution from sealed vials. The system is closed so that highly potent compounds can later be recovered and reworked without large investment in further engineering controls. The system includes three main components: a recovery device that holds sealed vials containing a solution, and provides means to access the contents of the vials; a peristaltic pump that pumps solution out of the vials; and a recovery tank that receives the pumped solution.

Abstract: A sample carrier generally comprises a sample node and an identifier co-located with the sample node. A sample node may be operative to carry a discrete sample, while an identifier may be operative to provide information associated with the sample carried by the sample node. Embodiments of a sample carrier may comprise a plurality of sample nodes supported in a predetermined spatial relationship relative to a respective sample container such as a respective well of a multi-well plate. A system and method of transferring specimens to a sample carrier include contacting a sample node to the specimen and encoding information associated with the specimen on the identifier. Various alternatives are disclosed wherein the specimen is solid, gaseous, and liquid in form.

Abstract: A hydraulic fluid sampler and a method for obtaining a hydraulic fluid sample includes a sample container holder configured to support a sample container mounted thereto in an inverted position and a non-inverted position. In the inverted position, the sample container holder is configured to flush the sample container with hydraulic fluid so as to flush away any contaminates that may be present. In the non-inverted position, the sample container holder is configured to fill the sample container with hydraulic fluid.

Abstract: The invention relates to a composite structure of a sample carrier 20 and a sample holder 30 for use in a TEM, for example. The sample carrier is hereby separately embodied from the sample holder. Although such compositions are already known, the known compositions are very fragile constructions. The sample carrier according to the invention can be formed from a strip of metal, and is a simple and cheap element. Using resilient force, it clamps onto or into the sample holder. The portion of the sample holder to which the sample carrier couples also has a simple form. The sample carrier can couple to the sample holder in vacuum using a coupling tool.

Abstract: The invention relates to a sample chamber with a cover plate and a bottom plate which is joined thereto in a fixed manner, wherein a recess is provided in the cover plate so that a reservoir is formed by the bottom plate, wherein a planar element with holes is provided in the reservoir, wherein the holes have a predetermined arrangement and/or size.

Abstract: The field of the present invention pertains to a controlled transfer biological collection device using a dry solid storage and transfer medium and a method for the collection of biological material of interest (genetic or proteinaceous material) in a form suitable for storage and/or subsequent analysis. Specifically, the present invention provides for a sampling device that controls the transfer of the biological sample to the storage medium by holding the storage medium and a moveable sample collection member having an analyte collection surface. The invention further provides for a method not only for storing a biological analyte on this collection device but also for analyzing the stored biological analyte using methods that are suited for automated analyzing systems.

Abstract: An ion implantation method for achieving angular uniformity throughout a workpiece and application thereof are provided. The ion beam has at least one beamlet striking the workpiece surface with corresponding incident angles. The workpiece is mapped to an imaginary planar coordinate system. The incident angle of a center beamlet of the ion beam has a projection on the coordinate system forming a projection angle with an axis thereof. A workpiece orientation of the workpiece is adjusted based on the projection angle such that the contribution of each beamlet to the overall ion beam intensity upon striking the workpiece surface is rendered substantially the same from respective directions of each of the coordinate axes.

Abstract: A specimen holder, a specimen inspection apparatus, and a specimen inspection method permitting a specimen consisting of cultured cells to be observed or inspected. Also, a method of fabricating the holder is offered. The holder has an open specimen-holding surface. At least a part of this surface is formed by a film. A specimen cultured on the specimen-holding surface of the film can be irradiated via the film with a primary beam for observation or inspection of the specimen. Consequently, the cultured specimen (e.g., cells) can be observed or inspected in vitro. Especially, if an electron beam is used as the primary beam, the specimen in vitro can be observed or inspected by SEM. Because the specimen-holding surface is open, a manipulator can gain access to the specimen. A stimulus can be given to the specimen using the manipulator. The reaction can be observed or inspected.

Abstract: A permeable-wall sample holder provides ventilation of vapor-phase entities between the sample and the exterior of the holder through its wall. The vapor-phase transport across the holder wall supports equilibrium of the sample with the analysis environment.

Abstract: A pressure source material is loaded into a space having constraint device 1, which is formed partly by optically transparent material 1a, 1b, and is disrupted under volume constraint. Light energy is externally supplied to the pressure source material constrained in the space through the optically transparent material by employing the device to apply light energy. The disruption of atomic bonds in the pressure source material is induced by heating the pressure source material above the boiling point thereof through the supplied energy. Exceptionally high pressures are generated in the space by the use of expansive forces arising from the disruption of atomic bonds. Such a configuration can implement ultrahigh pressure abilities that has not been achieved, so far.

Abstract: There is provided a mini environment type transfer unit which can efficiently transfer a sample to a critical dimension scanning electron microscope (CD-SEM) even in the case of use of a SMIF pod which can store only one photomask. In addition to a load port, a stocker which can store a plurality of photomasks is provided in the mini environment type transfer unit. A mask storage slot in which a plurality of storage units are stacked is provided in the stocker, and one photomask is stored in each storage unit. A sensor is provided in each storage unit to determine whether or not the photomask is normally stored. Additionally, a sensor is provided in each storage unit to detect whether or not the photomask exists.

Abstract: The present invention relates to a nanocell, and method for manufacturing same, for holding small volumes of soft matter confined in a gap of order 1 micrometer or smaller and measurement systems using the same. The nanocell comprise: a first structure (3) with a substantially flat surface in one direction; a second structure (6) with a substantially flat surface in one direction; and at least one spacer (1, 2); wherein said substantially flat surface of each first and second structure face each other and are separated by the at least one spacer and the two surfaces and the spacer together define a volume (7) between them for holding said soft matter or fluid, and the distance defined by the spacer between said surfaces of the first and second structure is less than 1 micrometer; the volume between the surfaces of the first and second structures and the spacer is in the range between 1 femto liters and 1 micro liters.

Abstract: A sample cell for an analysis instrument, having an outer body forming a sample reservoir therein; a directional fill valve disposed in an upper end of the outer body and forming an upper end of the sample reservoir, the fill valve for accepting a sample during filling, and preventing sample leakage while providing venting after filling; and a film covering a lower end of the outer body, and forming a bottom end of the sample reservoir, the film for presenting the sample to an analysis focal spot of the analysis instrument. The disclosed sample cell is especially suited for an x-ray analysis engine having a focal spot requiring alignment with the sample in the sample cell. At least one x-ray optic may be disposed in an excitation and/or detection path, requiring alignment to the focal spot, in e.g., a WDXRF or EDXRF system.

Abstract: Method and apparatus for parallel dispensing of powder samples is described. Powder samples are dispensed into at least two powder sample holders, each said sample holder having a through passage which preferably generally tapers from a first aperture through which powder is introduced into said passage and a second aperture through which powder, when permitted to do so, flows from said passage. The lower apertures of the sample holders are preferably sealed using a resilient film. The powder samples are dispensed by substantially simultaneously perforating the film covering each aperture and agitating the powder samples to cause them to flow from their respective sample holders. Also disclosed are a method of generating a library of powder samples and a library of powder samples.

Abstract: A sample cup for retaining a sample material to be subjected to an x-ray spectrochemical analysis. The sample cup comprises a cell body of a cylindrical configuration having an open top end and an open bottom end and defining a hollow between the two open ends, the open top end having an outer wall and an inner wall encircling the open top end. The outer wall and the inner wall extend axially and are positioned in concentric relationship with one another and form a reservoir space therebetween.

Abstract: A slide holder for mounting to a sample holder having a pair of openings therein, for a grinder/polisher includes a plate for receiving the slide. The slide holder includes a pair of stems extending from the plate and configured and spaced for receipt in the sample holder openings. A locking element is mounted to each stem. The locking elements are mounted to pivot eccentrically relative to a center axis of each stem. The stems are inserted into the sample holder openings and the locking elements are pivoted to lock the slide holder to the sample holder and to prevent the stems from disengaging from the sample holder.

Abstract: An apparatus for storing at least one specimen slide and at least one cassette comprising a sample that is embedded in a sample block and that is to be processed, a microtome comprising this apparatus, and a method for handling multiple cassettes and multiple specimen slides are described. A cassette magazine receives at least one cassette having at least one sample block. A slide magazine receives at least one specimen slide. At least one connecting element for connecting the cassette magazine and the slide magazine mechanically with each other is provided. This allows handling at least one cassette and at least one specimen slide together in a simple and efficient manner.

Abstract: The invention, in various embodiments, provides systems, methods and devices relating to processing a sample. Aspects presented herein relate to collecting, stabilizing, pulverizing, fragmenting, and/or analyzing biological and non-biological sample specimens. Before constituents of sample specimens are analyzed, the sample specimens may be fragmented into a plurality of smaller specimens. Such smaller specimens may then be stored, analyzed, or further processed.

Abstract: A sample frame (30; 81) for preparing a plurality of sample vessels (41, 42), in particular sample tubes, having a plurality of retainers, in each of which a sample vessel (41, 42) is situated, is characterized in that the sample vessels (41, 42) each have a cap (43, 44), which is put over the open end of the sample vessel (41, 42), the cap (41, 42) having a drilled hole (53, 54), through which the interior of the sample vessel (41, 42) is accessible, the sample frame (30; 81) has a removable cover plate (8), whose bottom side faces toward the caps (43, 44) of the sample vessels (41, 42) in the put-on state of the cover plate (8), and the cover plate (8) has an approximately funnel-shaped depression (11, 71) on the top side for each retainer, in whose center a through opening (57) through the cover plate (8) is provided, the through opening (57) aligning with the drilled hole (53, 54) of a cap (43, 44) of a sample vessel (41, 42) retained underneath when the cover plate (8) is put on.

Abstract: [Problems] It is intended to provide a storing device which is convenient in preserving a slice of a pathological tissue or the like over a long time and by which a required number of slices can be quickly provided without waste. It is also intended to provide an instrument for microscopic observation which is equipped with this storing device and a transparent plate having an adhesive layer formed thereon. [Means for Solving Problems] A device comprising: a piece of a resin film on which a slice having been excised from a sample block or a cell block slice is adhered and fixed via an adhesive layer provided on the surface thereof; and a holder on the surface of which the back face of the film piece is detachably adhered and fixed via a pressure-sensitive adhesive layer. An instrument for microscopic observation which comprises the storing device and a transparent plate for adhering and fixing the film piece having been peeled off from the storing device.

Abstract: A device for receiving liquid samples includes at least one sample carrier (1) for receiving the liquid sample, a sample carrier ejector (3) and a sample carrier holder (2) with a first guiding area and a second guiding area (4, 5) for guiding the sample carrier ejector (3). The first guiding area (4) has a tubular design and the second guiding area (5) has a groove-shaped design. The sample carrier ejector (3) has a geometry complementary to the first and second guiding areas (4, 5) and is axially displaceable within the sample carrier holder (2) such that the sample carrier (1) can be detached by the sample carrier ejector (3) from the sample carrier holder (2).

Abstract: A device for collecting a sample and for depositing the sample in a sample-receiving port of a measuring apparatus comprises a first connection element (8) with three connections for fluid, and a second connection element (7), and a hollow needle (5) for collecting and depositing the sample. A first feed line (9) for a first washing liquid is connected via a first pump to a first connection for fluid of the first connection element (8). A second feed line (10) for a second washing liquid is connected via a second pump to a second connection for fluid of the first connection element (8). A connection for fluid of the second connection element (7) is connected to the third connection for fluid of the first connection element (8), and the second connection element (7) is connected to a dosing device (1) and to the hollow needle (5). A valve (2) is arranged between the third connection for fluid of the first connection element (8) and the second connection element (7).

Abstract: The present invention includes a system and method for the management of specimens ordinarily manipulated via tubes. The invention may include a flexible, removable tube holder that is linear when placed in a rack and curved when placed into a centrifuge rotor. The system provides for the elimination of manual recording of the individual tubes, and also provides for the transference of the tubes from the rack to the centrifuge and back in a group.

Abstract: It is an object of this invention to provide a sample integration cassette, a spotting device and a sample integration device which enhance a sample integration density and reduce the size of a sample assembly and a probe. The sample integration cassette has the sample assembly and the sample support carrier so arranged therein that the sample support can be fed from the sample support carrier onto the sample assembly at a predetermined angle to the sample assembly at all times. The cassette is formed so as to be connectable with a drive unit that applies a drive force to the sample assembly and the sample support carrier interlockingly and synchronously. The spotting device has a delivery member mounting table which is vertically moved over the sample support carrier to apply samples to the sample support from the delivery member.

Abstract: This invention relates to a kit to enable the bio-degradability of a material to be observed. The kit includes: at least one environmental vessel formed from a non bio-degradable material having an opening that can be covered with a scalable lid for loading of the vessel, which vessel includes means so that the vessel can be sealed or ventilated if desired; at least one sample of a material to be tested. The sample to be tested can be located in the vessel and tested under the influence of a particular environment, which environment may be ventilated if desired.

Abstract: For the simplified use of a test strip holder, a device having a holding or positioning device is provided, comprising a mixing chamber, a lid for closing the mixing chamber, and an obvious fluid opening for a fluid passage from the mixing chamber to the test strip holder. This allows for the test strip holder to be inserted into the device in a simple way and a sample can be prepared in the mixing chamber of the device. The device is provided with a mixing chamber that can be closed, wherein a reaction partner, for example a gold conjugate, can be dissolved in the sample for increasing the sensitivity of the test strip.

Abstract: The invention describes a diagnostic device in a substantially fluidtight housing in which a diagnostic or test material is transported via an aperture in the housing for (multiple, continuous or discontinuous) measurements of a compound or condition of the environment, e.g. a liquid medium. Preferably the measurement is an optical or electrical measurement. Data from the measurement are transmitted wirelessly to a receiver station which is connected to a computer (network) for further processing and/or display of the data.

Abstract: The invention concerns a secure method for collecting and analyzing samples using a device for storing samples comprising data storage means and at least one sampling receptacle capable of being associated therewith, the device being provided with means for verifying and ensuring the integrity of the receptacle before and after its use when said receptacle is associated with the device, the receptacle including data storage means already including data for identifying said receptacle, the method providing for recording of all data concerning sampling and analysis in the storage means.

Abstract: Because a sample holder 100 is composed of a plurality of convex parts 1 provided on a top face of a base substance 2, and the plurality of convex parts 1 are spherical surfaces 1a formed of a single crystal or amorphous material, frictional wear of the sample at contact parts between a sample 4 and the convex parts 1 is reduced, thereby making it possible to inhibit particle generation. Further, because a joining layer 3 is formed of a single crystal or amorphous material, there is no defect that particles scattered on the sample holder 100 fill up it, which makes it possible to easily keep it in a clean state by cleaning, and it is possible to effectively reduce reattachment of particles to the sample 4.

Abstract: A method is provided for determining the presence and/or concentration of at least one contaminant in a subsurface at a test site. The method generally includes inserting a sampling assembly into at least one tree at the test site, processing at least part of the sampling assembly to determine if a contaminant is present in the at least one tree, and then correlating the presence and/or concentration of the contaminant in the at least one tree to presence and/or concentration of the contaminant in the subsurface. The sampling assembly is operable to sorb at least one contaminant located within the at least one tree to at least part of the sampling assembly. The sampling assembly may include a solid phase microextraction (SPME) sampling assembly having a SPME sampling device and a support configured to help position the SPME sampling device within a tree for sampling operation.

Abstract: A system incorporating a balanced mechanical resonator and a method for vibration of a sample composed of granular material to generate motion of a powder sample inside the sample holder for obtaining improved analysis statistics, without imparting vibration to the sample holder support.

Abstract: A sample carrier having a top wall, a base, and a support wall joining the top wall and the base. The top wall includes aligned, spaced-apart openings on at least one side of the support wall which are sized to receive sample tubes. Sleeves depending from the top wall and circumscribing each opening direct sample tubes into sample tube holding areas. The sample tube holding areas each include one or more retaining walls extending upward from the base opposite the support wall. Springs extending outward from the support wall bias sample tubes against the retaining walls. A drip shield comprising a cover plate, a pair of through-holes for accessing sample tubes in the sample carrier, and a depending fin which separates sample tubes on opposite sides of the support wall protects against cross-contamination between sample tubes held by the sample carrier.

Abstract: A device and method of securing the original biological specimen collection absorbent within a holder to permit use of the absorbent within automatic specimen analysis devices and to permit continuance of a chain of custody is provided.

Abstract: The present invention relates to a device and system from doing mechanical and electrical measurements and manipulation on nano or micro sized objects using a sample holder adapted to fit in situ of a transmission electron microscope. The sample holder comprise at least two arms each with at least one connector whereby the sample (206) may be mounted between the two connectors forming a bridge closing a gap between the two arms of the sample holder. The sample holder is arranged to provide mechanical forces to a sample mounted on the sample holder and measuring and/or applying electrical signals from the sample while at the same imaging using the transmission electron microscope. Each arm of the sample holder may comprise three substantially parallel beams for electro-thermal actuation.

Abstract: There is disclosed a method of testing oil extraction processes including the steps of: 1) placing a sample to be tested in a sample holder which has a configurable temperature profile; 2) placing the sample holder in a pressure vessel; 3) increasing the pressure in the pressure vessel to simulate an over burden pressure; 4) configuring the temperature profile of the sample holder to match a desired temperature profile; 5) applying an oil extraction process to the sample; 6) measuring one or more parameters of the oil extraction process; 7) measuring the temperature of the sample to which the process is being applied; 8) configuring the sample holder to match the measured temperature profile. A device to test oil extraction processes on samples is disclosed. The device has a temperature configurable sample holder having sufficient temperature control to provide a desired heat profile to the sample.

Abstract: A sample working/observing apparatus possesses a sample holding mechanism. The sample holding mechanism possesses a sample holder holding a sample, and a base detachably supporting the sample holder. Between these, there are detachably provided a rotation support part supporting so as to be rotatable, a slide support part supporting so as to be slidable from a rotation center toward an X-direction, and a butting support part supporting so as to be slidable in the X-direction and a Y-direction. In an upper face, there are provided an X-direction positioning pin and a Y-direction positioning pin, which are disposed along the Y-direction and the X-direction from the rotation center, and butt against one side and the other side of the sample.

Abstract: A container for storing a biological sample is disclosed. The container includes a first chamber having a sidewall extending between an open end and a closed end, defining a first chamber interior adapted to receive a sample holder therein. The container also includes a second chamber having a sidewall extending between an open end and a closed end, defining a second chamber interior adapted to subsequently receive the sample holder therein. The second chamber interior is in fluid isolation from the first chamber interior. A removable closure encloses at least one of the open end of the first chamber and the open end of the second chamber while the sample holder is disposed within one of the first chamber interior and the second chamber interior. A first fluid may be disposed within the first chamber interior, and a second different fluid may be disposed within the second chamber interior.

Abstract: Dissolution test equipment (e.g., apparatus) and methods for testing are disclosed. Such methods and equipment may be advantageously used for testing of drug or active pharmaceutical ingredient (API) preparations, including drug formulations and dosage forms.

Abstract: A specimen container holder (12) aids in the collection of a biological specimen (16). The holder (12) securely holds and supports a specimen container (14) in a gripping unit (88) made of two arcuate fingers (36) and (40) attached to a handle (28). Subsequent to specimen collection, the specimen container (14) can be disengaged from the holder (12) by pressing (104) on the handle (28) with one hand.

Abstract: The invention generally relates to atomic resolution imaging, and, more particularly, to systems and methods for calibrating an atomic resolution measurement tool. A sample holder for holding test samples used in measuring linearity of an atomic force microscope is provided. The holder includes a body having a top surface, and a plurality of inclined regions formed in the body and spaced apart along the top surface. Each of the inclined regions is structured and arranged to hold a test sample used to measure linearity of an atomic force microscope at one of a plurality of predefined angles.

Abstract: A device for performing biological sample reactions may include a plurality of flow cells configured to be mounted to a common microscope translation stage, wherein each flow cell is configured to receive at least one sample holder containing biological sample. Each flow cell also may be configured to be selectively placed in an open position for positioning the at least one sample holder into the flow cell and a closed position for reacting biological sample contained in the at least one sample holder. The plurality of flow cells may be configured to be selectively placed in the open position and the closed position independently of each other.

Abstract: A liquid sample holder prevents the removal of liquid or vapor portions of a sample material from a sample reservoir when a working fluid is desorbed from the sample material. The apparatus includes a sample reservoir and a liquid trap, both of which are contained in a housing. The liquid trap is positioned above the sample reservoir, and a flow path is configured to fluidly couple the sample reservoir to a gas port located in an upper portion of the housing by passing through the liquid trap. The liquid trap may include a baffle assembly, a porous mesh of high surface area material, or a combination of both.

Abstract: A docking mechanism provided for analytical apparatus, such as an acoustic bio-sensor apparatus. The mechanism is operable releasably to receive a cartridge (58) for use in analysing a sample comprising a fluid and having a flow cell (104, 106; 304, 306) for the sample and an electrically operated sensor (92) for performing the analysis. The docking mechanism has a clamping mechanism (12, 8, 10) for urging fluid connector means such as ferules (50, 52) against the cartridge to provide a fluid connection between the flow cell inlet and a sample delivery means.

Abstract: Provided is an apparatus for automated separation of a target component from a sample using magnetic particles, which apparatus comprises a reagent delivery device and a vial holder for holding one or more vials in position, in which the reagent delivery device is alignable with the one or more vials for reagent delivery thereto; wherein means are provided to vary the angle of incidence of reagent delivery relative to an internal wall of the one or more vials.

Abstract: There is provided a sample trituration vessel that even when the sample is relatively hard, enables triturating of the sample easily and with high efficiency. The sample trituration vessel comprises a tubular body (22) having an opening (21) at one end and having a bottom part (23) at the other end thereof. The tubular body (22) is furnished with a rugged portion (25) there-inside so as to be able to meet another rugged port (44) formed on a trituration rod (40). The sample trituration vessel itself can exert shearing effect on the sample. The tubular body (22) is formed of flexible material, and upon application of external force from outside of the tubular body (22), the tubular body (22) is deformed, thereby breaking down the sample held within the tubular body (22).

Abstract: The present disclosure provides a polar coordinate positioning system. The system can be used, for example, to sample a microtiter plate or sample tubes. In some embodiments, the system orients a sample with respect to a sampling tool using polar coordinates. In some embodiments, the sample is configured to rotate about an axis and move linearly in a direction transverse to the axis, and the sampling tool is configured to move linearly in a direction transverse to the linearly movement of the sample.

Abstract: The present invention provides a method of testing for the presence of infectious disease agents or host genetic markers comprising applying a device comprising an absorbent and porous material onto the introitus of a female patient; encouraging air drying of at least a portion of the collected vaginal discharge while the device is proximate to the introitus; and determining the presence of infectious disease agents or host genetic markers in the at least partially dried vaginal discharge.

Abstract: An apparatus and method for collecting, sorting and storing samples from multiple batches of copper cathode is disclosed. Samples are collected at a sampling station and transferred to a collection container. The samples are then transferred to a sorting container by way of chutes forming a continuous path from the collection container to the sorting container. The sorting container is affixed on the top surface of an automated carousel having a plurality of sorting containers for sorting samples from multiple batches. Samples in the sorting containers are recovered into storage containers through an access door panel and a funnel placed beneath the access door.

Abstract: Medical and environmental diagnostic devices are described and claimed. Preferred embodiments feature cup (1) within cup configurations wherein one cup is dedicated, for the most part, to sample collection and another cup (2) is dedicated, for the most part, to assay performance. Communication between the cups is afforded by what is believed to be a unique valve assembly (3) and lid (7) tandem.