Abstract: There is disclosed novel Phellinus linteus Yoo. This mushroom is identified as novel as analyzed by restriction fragment length polymorphism and by microbiological features. A polysaccharide substance isolated from the fruiting bodies or mycelia the strain and other Phellinus spp. has an anticancer activity by inciting the cytotoxicity of T-cells and the antibody forming potency of B-cells. Also, the polysaccharide substance shows a potent activity against cancer metastasis. The polysaccharide substance, which can stimulate the immunity of the body, may be effective in the prophylaxis and treatment of immune-related diseases, such as cancers and AIDS, and in the study on the basic mechanism of the diseases.
Type:
Application
Filed:
May 1, 2001
Publication date:
November 29, 2001
Applicant:
KOREA INSTITUTE OF SCIENCE & TECHNOLOGY
Inventors:
Ick-Dong Yoo, Soo-Muk Cho, Byeung-Wook Park, Jae-Kuk Yoo, Nam-Doo Hong, Hwan-Mook Kim, Sang-Bae Han, Chang-Wood Lee