Containing Sulfur (see Note 4) Patents (Class 930/24)
  • Radiolabelled peptide compounds
    Patent number: 5371184
    Abstract: A diagnostic composition suitable for administration to a warm-blooded animal comprising hirudin or a molecule capable of interacting with the hirudin receptor labeled with a radionuclide by means of a chelate ligand capable of administration to an animal to produce reliable visual imaging of thrombus.
    Type: Grant
    Filed: February 5, 1992
    Date of Patent: December 6, 1994
    Assignee: Mallinckrodt Medical, Inc.
    Inventors: Raghavan Rajagopalan, Leon R. Lyle, Thomas J. Dunn
  • Renin inhibiting compounds
    Patent number: 5250517
    Abstract: Compounds which are amino acid derivatives and have the formula ##STR1## in which R.sup.1 is hydrogen or methyl, R.sup.2 is ethyl, propyl or imidazol-4-yl, R.sup.3 is isobutyl, cyclohexylmethyl or benzyl, and A is defined as herein are useful as renin inhibitors.
    Type: Grant
    Filed: May 4, 1992
    Date of Patent: October 5, 1993
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Quirico Branca, Albrecht Edenhofer, Eva-Maria Gutknecht, Werner Neidhart, Henri Ramuz, Wolfgang Wostl