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  • Patent number: 6673340
    Abstract: Novel insect toxins are disclosed for use in pesticidal compositions and methods. According to the invention basement membrane degrading proteases are identified which are capable of acting as insecticidal agents. Polynucleotides are provided which include expression constructs for the expression of the recombinant insecticidal proteases of the invention as recombinant insect pathogens, as well as transgenic plants with a substantial degree of insect resistance.
    Type: Grant
    Filed: July 12, 2000
    Date of Patent: January 6, 2004
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Robert L. Harrison, Bryony C. Bonning
  • Patent number: 5643776
    Abstract: A diagnostic or control composition is useful to characterize or control insects and comprises a nucleotide sequence coding for juvenile hormone esterase (JHE). The coding sequence may be combined with a promoter sequence regulating the transcription thereof in a recombinant expression vector for use in controlling insects having a juvenile hormone esterase dependency. Preferred embodiments of the invention are recombinant baculoviruses in which a mutated JHE coding sequence provides relatively rapid speed of kill in insects.
    Type: Grant
    Filed: August 10, 1992
    Date of Patent: July 1, 1997
    Assignee: The Regents of the University of California
    Inventors: Bruce D. Hammock, Terry N. Hanzlik, Lawrence G. Harshman, Bryony C. Bonning, Vernon K. Ward
  • Patent number: 5674747
    Abstract: A diagnostic or control composition is useful to characterize or control insects and comprises a nucleotide sequence coding for juvenile hormone esterase (JHE). The coding sequence may be combined with a promoter sequence regulating the transcription thereof in a recombinant expression vector for use in controlling insects having a juvenile hormone esterase dependency. Preferred embodiments of the invention are recombinant baculoviruses in which a mutated JHE coding sequence provides relatively rapid speed of kill in insects.
    Type: Grant
    Filed: May 12, 1995
    Date of Patent: October 7, 1997
    Assignee: The Regents of the University of California
    Inventors: Bruce D. Hammock, Terry N. Hanzlik, Lawrence G. Harshman, Bryony C. Bonning, Vernon K. Ward