Patents Represented by Attorney A. J. Moore
  • Patent number: 6987123
    Abstract: The present invention relates to compounds of the general formula (I), there derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their pharmaceutically acceptable salts, and their pharmaceutically acceptable solvates, wherein all variables are as defined in the specification.
    Type: Grant
    Filed: August 10, 2001
    Date of Patent: January 17, 2006
    Assignee: Cadila Healthcare Limited
    Inventors: Braj Bhushan Lohray, Vidya Bhushan Lohray, Vijay Kumar Gajubhai Barot
  • Patent number: 6759663
    Abstract: The present invention provides devices and methods for detection of particles, such as biological cells, in samples using a photosensitive waveguide. The photosensitive waveguide changes its transmissivity in a detectable manner in response to controlling radiation emitted from the particles. In preferred embodiments, the waveguide is two-dimensional and the position of the particles as well as their presence is obtained by scanning the waveguide in two non-parallel directions. The provided devices are preferably used to locate labeled cells. The present invention also includes control systems and methods for detecting and locating cells using the devices provided.
    Type: Grant
    Filed: July 22, 2002
    Date of Patent: July 6, 2004
    Assignee: Ikonisys, Inc.
    Inventors: Petros Tsipouras, Triantafyllos Tafas
  • Patent number: 6635763
    Abstract: The present invention relates to a process for the preparation of thieno[3,2-c]pyridine derivatives having pharmacologically significant anti-aggregating and anti-thrombotic properties.
    Type: Grant
    Filed: October 22, 2001
    Date of Patent: October 21, 2003
    Assignee: Cadila Health Care Limited
    Inventors: Bipin Pandey, Vidya Bhushan Lohray, Braj Bhushan Lohray
  • Patent number: 6265167
    Abstract: The invention pertains to a novel method and construct for regulating gene expression through inhibition of gene expression by nuclear antisense RNA. The construct provides an efficient means for introducing, expressing and accumulating the antisense RNA in the nucleus. The antisense RNA hybridizes to the sense mRNA in the nucleus, thereby preventing both processing and cytoplasmic transport. The construct comprises a promoter, antisense sequences, and a cis- or trans-ribozyme which generates 3′-ends independently of the polyadenylation machinery and thereby inhibits the transport of the RNA molecule to the cytoplasm. The construct may also comprise a histone stem-loop structure that assists in stabilizing the transcripts against exonucleolytic degradation.
    Type: Grant
    Filed: May 18, 1999
    Date of Patent: July 24, 2001
    Inventors: Gordon G. Carmichael, David B. Batt, Zhong Liu
  • Patent number: 6253427
    Abstract: An improved garment loop for engaging and disengaging a button is described which includes at least one aperture for receiving a pin element. In a preferred embodiment, the loop is manufactured from a single piece of wire which provides for resilient movement of a button receiving portion by way of an overlapping element structure comprising a horizontal strap bar which includes a pair of generally flat stamped elements engaged together with a riveted pin.
    Type: Grant
    Filed: July 1, 1999
    Date of Patent: July 3, 2001
    Inventor: Stuart Gerson
  • Patent number: 6137082
    Abstract: A brush block assembly, for providing stationary mounting of electrically conductive brushes in contact registration with associated slip rings of a rotating interface, comprises a main housing adapted for mounting in proximity to the rotating interface and having a recess portion for releasably engaging a brush holder, and a brush holder formed from a thermoplastic molding compound comprising an organic polytetrafluoroethylene (PTFE) filler distributed within a polyetheretherketone (PEEK) thermoplastic resin, for securing the brushes within the recess in contact registration with their associated slip rings.
    Type: Grant
    Filed: May 29, 1998
    Date of Patent: October 24, 2000
    Assignee: United Technologies Corporation
    Inventors: Robert W. Pruden, Daniel J. Madar
  • Patent number: 6069341
    Abstract: The brush block housing for providing stationary mounting of graphite composition brushes in contact registration with the rotating interface slip rings of an aircraft propeller deicing system, is formed from a thermoplastic molding compound comprising an organic polytetrafluoroethylene (PTFE) filler distributed within a polyetheretherketone (PEEK) thermoplastic resin, thereby minimizing non-functional abrasion of the brushes.
    Type: Grant
    Filed: May 29, 1998
    Date of Patent: May 30, 2000
    Assignee: United Technologies Corporation
    Inventors: Marc E. Gage, Robert W. Pruden
  • Patent number: 6012676
    Abstract: An integrated fire and flight control (IFFC) system senses the actual engine torque of a rotary wing aircraft in successive real time intervals and compares the sensed interval values with one or more reference maximum torque limits for each of one or more prescribed maximum time intervals and, in the presence of an above limit actual torque for an above limit prescribed time interval, the IFFC automatically reduces the collective axis command.
    Type: Grant
    Filed: March 31, 1998
    Date of Patent: January 11, 2000
    Assignee: Sikorsky Aircraft Corporation
    Inventors: Phillip J. Gold, Donald L. Fogler, Jr.
  • Patent number: 5925852
    Abstract: A structure for making a sealed electrical connection through a barrier is disclosed. The structure comprises a feed-through board that is sealed in an aperture in the barrier. A conductive rod is disposed within a bore formed in the board. Inner and outer conductors are electrically connected to the conductive rod by means of connecting structures formed in the respective ends thereof. A plurality of layers of insulative materials are formed about the inner and outer conductors and the conductive rod so as to electrically insulate the conductors and the conductive rod, to form a structurally sound point of connection through the barrier, and to seal the bore through which the conductive rod is passed. A method for making a sealed electrical connection through a barrier is also disclosed.
    Type: Grant
    Filed: August 11, 1998
    Date of Patent: July 20, 1999
    Assignee: Caterpillar Inc.
    Inventors: Joseph P. Hinz, Jeffrey A. Hudson
  • Patent number: 5667986
    Abstract: A yeast promoter comprising the promoter of the (cytoplasmically located glycerol-3-phosphate dehydrogenase gene (GPD 1) possesses advantageous capacity to regulate the expression of heterologous polypeptides in yeasts transformed therewith. Expression of such polypeptides utilizing the GPD1 promoter can be regulated by the presence(repressed) or absence(derepressed) of high levels of sucrose or glucose in the fermentation medium. Alternatively, a non-repressing carbon source, such as glycerol or ethanol, can be added to the fermentation medium.
    Type: Grant
    Filed: July 1, 1994
    Date of Patent: September 16, 1997
    Assignee: Delta Biotechnology Limited
    Inventors: Andrew R. Goodey, Darrell Sleep, Dina Vakeria
  • Patent number: 5637504
    Abstract: A 2 .mu.m plasmid vector for transforming yeast, especially brewing yeast, much which comprises a DNA sequence allowing propagation of the plasmid in bacteria, two copies of the 74 base pair FLP recombination site of the 2 .mu.m plasmid in direct orientation and a DNA sequence coding for a protein or peptide of interest. The plasmid is so constructed that in yeast the bacterial DNA sequence is between the two recombination sites which are in direct orientation and is spontaneously lost following recombination. A "gene of interest" is preferable inserted at the SnaBI site.
    Type: Grant
    Filed: September 19, 1994
    Date of Patent: June 10, 1997
    Assignee: Delta Biotechnology Limited
    Inventors: Edward Hinchliffe, Simon A. Chinery
  • Patent number: 5625041
    Abstract: Problem: when proteins are purified using a protein-binding dye immobilised on a chromatographic matrix, the dye or a portion/derivative may leak into the eluant. Solution: an ion-exchange resin (e.g. Dowex-1) and a disrupting material (e.g. salt and a fatty acid such as sodium octanoate) are used to separate the dye from the protein.
    Type: Grant
    Filed: November 22, 1994
    Date of Patent: April 29, 1997
    Assignee: Delta Biotechnology Limited
    Inventors: Richard A. Johnson, Alan V. Quirk, John R. Woodrow
  • Patent number: 5245916
    Abstract: A cartridge-carrier is disclosed for maintaining at least one filled and sealed, plastic container within at least two segments which are joined together to define a tubular cartridge having at least one container supporting plate therein for receiving a body of said at least one sealed container and thereafter closing at least the two segments for encompassing at least one container within a tubular cartridge which is then moved into a cylindrical carrier that enables the containers to be processed within a reel and spiral sterilization system.
    Type: Grant
    Filed: July 29, 1991
    Date of Patent: September 21, 1993
    Assignee: FMC Corporation
    Inventors: Rey A. Elizondo, Terry L. Heyliger, Joost Veltman
  • Patent number: 5149910
    Abstract: Composite armor comprising a corrugated metal spoiler plate in front of and spaced from high alumina ceramic tiles backed by an aluminum anvil.
    Type: Grant
    Filed: March 8, 1966
    Date of Patent: September 22, 1992
    Assignee: FMC Corporation
    Inventor: Gregg L. McKee
  • Patent number: 5135714
    Abstract: A process is provided for sterlizing a web of packaging materials which is to be formed into containers for aseptic packaging. The process comprises contacting the web with aqueous solution of ozone and hydrogen peroxide and subsequently irradiating the surface with ultra-violet radiation.
    Type: Grant
    Filed: March 8, 1990
    Date of Patent: August 4, 1992
    Assignee: FMC Corporation
    Inventor: James J. Wang
  • Patent number: 5134954
    Abstract: An asymmetrically arranged hydrofoil and propeller system is disclosed for improving the speed and lift of watercraft such as amphibious vehicles. When the vehicle is propelled through water by propellers, a downwash of water from the upper surface of the asymmetrically arranged hydrofoils is intercepted by upwardly moving propeller blades which improve the speed, lift and efficiency of the watercraft.
    Type: Grant
    Filed: October 24, 1990
    Date of Patent: August 4, 1992
    Assignee: FMC Corporation
    Inventors: Christopher D. Barry, Bryan Duffty
  • Patent number: 5131523
    Abstract: An apparatus and a method of conveying, queuing and transferring articles laterally in a direction different from the original direction of conveyance utilizing a cam means to harness the movement of an indexing conveyor system.
    Type: Grant
    Filed: May 6, 1991
    Date of Patent: July 21, 1992
    Assignee: FMC Corporation
    Inventor: Christopher L. Codde
  • Patent number: 5122323
    Abstract: A method for rapidly forming composites by rotating an alterable male mold to wrap a plurality of continuous and intermittent layers of uncured laminate around the male mold when in a closed position and allowing the male mold to be moved into a female mold and to thereafter sever all layers on the male mold into an open position which thereafter transfers the resin matrix composite to a female mold which shapes the composite in a desired configuration and thereafter heat cures the composite lay-up material while being subjected to a vacuum. A second embodiment of the invention uses a non-rotatable male mold.
    Type: Grant
    Filed: April 24, 1991
    Date of Patent: June 16, 1992
    Inventor: Fletcher R. Sullivan, Sr.
  • Patent number: 5115843
    Abstract: A common base for a plurality of fillers is disclosed for supporting a plurality of type of container fillers. A common drive system for the plurality of fillers is supported by a single plate, and drives a star wheel for moving containers below a plurality of filler valves for receiving a predetermined volume of flowable product. The power means rotates a plurality of selected types of filling valves, and means are provided for raising and lowering pistons in said cylinders for filling containers of variable sizes.
    Type: Grant
    Filed: November 8, 1990
    Date of Patent: May 26, 1992
    Assignee: FMC Corporation
    Inventor: William M. Bayliss
  • Patent number: 5106282
    Abstract: An apparatus is disclosed for rapidly laying up and curing thick complex shaped resin matrix composites connected to a rotatable and alterable male mold to wrap a plurality of continuous and intermittent layers of uncured laminate around the male mold when said mold is in a closed position; moving the male mold into a female mold and thereafter severing all layers on the male mold and articulate the male mold to an open position which shapes the upper regions of the composite and thereafter transferring the resin matrix composite to a female mold which shapes the composite in a desired configuration and thereafter heat cures the composite lay-up while being subjected to a vacuum. A second embodiment of the invention uses a non-rotatable male mold.
    Type: Grant
    Filed: December 18, 1989
    Date of Patent: April 21, 1992
    Assignee: FMC Corporation
    Inventor: Fletcher R. Sullivan, Sr.