Abstract: The present application relates to the uses of phenylacetic acid benzylamides and new (S)(+)-2-ethoxy-4-[N-[1-2-piperidino-phenyl)-3-methyl-1-butyl]-aminocarbon ylmethyl]-benzoic acid and the salts thereof, which have valuable pharmacological properties, namely an effect on the intermediate metabolism, but particularly the effect of lowering blood sugar.
Type:
Grant
Filed:
May 9, 1994
Date of Patent:
November 7, 2000
Assignee:
Karl Thomae GmbH
Inventors:
Wolfgang Grell, Rudolf Hurnaus, Gerhart Griss, deceased, Robert Sauter, Manfred Reiffen, Eckhard Rupprecht
Abstract: Compounds of the formula ##STR1## which is explained more fully in the specification, may be prepared by conventional methods and used therapeutically in conventional galenic preparations.
Type:
Grant
Filed:
June 5, 1995
Date of Patent:
March 14, 2000
Assignee:
Boehringer Ingelheim KG
Inventors:
Ralf Anderskewitz, Kurt Schromm, Ernst-Otto Renth, Frank Himmelsbach, Franz Birke, Armin Fugner
Abstract: Milling/sizing apparatus which includes individual and/or nested sieves each of which may also include a quantity of beads, disks and/or other geometric or non-geometric shapes. The sieves can be rotated, vibrated or agitated in any and all combinations by various methods to achieve independently horizontal rotation and vertical reciprocation (similar to a merry-go-round) to efficiently segregate, size or mill cohesive and polydisperse powder particles to specific size ranges. The invention also contemplates a method for using the apparatus in the sizing and quantification of aggregated particles of cohesive disperse powders.
Type:
Grant
Filed:
December 9, 1998
Date of Patent:
March 14, 2000
Assignee:
Boehringer Ingelheim Pharmaceuticals, Inc.
Abstract: The invention relates to the use of carbocyclically and heterocycally fused dihydroyridines as cerebroprotective agents, as agents for treating chronic inflammatory processes and as agents for inhabiting blood clotting, and also relates to new compounds of formula Ie ##STR1##
Type:
Grant
Filed:
June 1, 1995
Date of Patent:
March 7, 2000
Assignee:
Boehringer Ingelheim KG
Inventors:
Walter Losel, Otto Roos, Dietrich Arndts, Franz Josef Kuhn, Ilse Strelle
Abstract: Disclosed are novel pyridodiazepines. These compounds, as well certain known 6,11-dihydro-5H-pyrido[2,3-b][1,5]benzodiazepin-5-ones are useful in the treatment of AIDS, ARC and related disorders associated with HIV infection.
Type:
Grant
Filed:
August 17, 1994
Date of Patent:
November 5, 1996
Assignee:
Boehringer Ingelheim Pharmaceuticals, Inc.
Inventors:
Karl D. Hargrave, Gunther Schmidt, deceased, Wolfhard Engel, Gunther Trummlitz, Wolfgang Eberlein