Abstract: The present invention relates to anti-S1P agents, particularly humanized monoclonal antibodies (and antigen binding fragments thereof) specifically reactive with S1P, compositions containing such antibodies (or fragments), and the use of such antibodies (or fragments), for example, to treat diseases and conditions associated with aberrant levels of S1P.
Type:
Grant
Filed:
October 24, 2008
Date of Patent:
September 27, 2011
Assignee:
Lpath, Inc.
Inventors:
Roger A. Sabbadini, William A. Garland, Genevieve Hansen, Steven Tarran Jones, David Williams
Abstract: The present invention relates to sequentially arranged streptavidin-binding binding modules which may in particular be used as affinity tags. The affinity tags comprise at least two individual modules capable of mediating avidic binding to streptavidin.