Abstract: Aqueous compositions, test kits and methods can be used to detect hydrogen peroxide or vanadium bromoperoxidase by generating a chemiluminescent signal in the presence of the analyte. Signal generation as well as reaction kinetics are improved by using a composition which comprises a 2,3-dihydro-1,4-phthalazinedione derivative; a halogen, pseudohalogen, halogen-providing or pseudohalogen-providing source; and a peroxide or peroxide-generating reagent composition.
Type:
Grant
Filed:
September 1, 1995
Date of Patent:
September 22, 1998
Assignee:
Johnson & Johnson Clinical Diagnostics, Inc.
Inventors:
Alan Eric Friedman, Sarah Fingar Groulx, Alison Butler