Abstract: Compounds of formula (I): where X is N or CH; A represents a group of formula (a) or (b) R1 represents hydrogen or an —NH2, —NR3R4, —NR3CO(C1-C4)Alk or —NR3SO2(C1-C4)Alk group; R2 represents hydrogen, a halogen or a (C1-C4)Alk, (C1-C4)alkoxy, —COOH, —COO(C1-C4)Alk, —CN, —CONR3R4, —NO2, —SO2NR3R4 or —NHSO2(C1-C4)Alk; m and n each represent 0, 1 or 2; R3 and R4 each represent hydrogen or a (C1-C4)Alk group; Y1 and Y2 each represent NH or O; and their salts or solvates, a process for their preparation and the pharmaceutical compositions comprising them.

Abstract: The present invention provides a method of treating or preventing migraine comprising administering to a patient in need thereof an effective amount of a selective iGluR5 receptor antagonist. The present invention further provides novel compounds functional as selective iGluR5 receptor antagonists as well as compositions and formulations comprising said selective iGluR5 receptor antagonists.

Abstract: In an integral drip molding in which a window guard section 21 along the front window W and a roof guard section 22 along the roof R are integrally formed, a lip section that contacts the front window W or the roof R is of a double construction, having an outer lip section 25 and inner lip section 26. The inner lip section 26 in the roof guard section 22 is positioned within a concave groove 28 formed at the portion where the roof R and the side panel 3 are connected, so that water that is forced into the rear section of the window guard section 21 flows into the concave groove 28 through a space S between the two lip sections 25 and 26. Thus overflow of water from the rear end of the window guard section to the side window is reliably prevented.

Abstract: The present invention provides compounds of Formula I or Formula II, or the pharmaceutically acceptable salts or prodrugs thereof, pharmaceutical compositions comprising compounds or Formula I or Formula II, and methods for treating neurological disorders and neurodegenerative diseases, particularly migraine.

Abstract: The invention concerns phenoxypropanolamines of formula (I) in which R1 represents a hydrogen, a group —S(O)z—(C1-C4)alk-R?, (R? being H, phenyl or (C1-C4)alkoxy), —NHSO2—(C1-C4)alk or NHCO(C1-C4)alk; m and n are each independently 0, 1 or 2; R2 and R3 independently represent a hydrogen, a (C5-C6)alkyl, (C3-C6)cycloalkyl, (C1-C4)alkoxy, hydrogen(C1-C4)alkoxy-(C1-C4)alkyl, mono- or di(C1-C4)alkamino(C1-C4)alkyl, pyrrolidino(C1-C4)alkyl, phenylamino or (C2-C4)alkenyl group, an aromatic or heteroaromatic group optionally substituted with a group R4, an aralkyl or heteroaralkyl group optionally substituted with a group R4, R2 and R3 can also together constitute a saturated or unsaturated ring of 3 to 8 atoms possibly bearing a (C1-C4)alkyl, amino (C1-C4)alkyl, carbamoyl or benzyl substituent; R4 represents a hydrogen or a halogen, or a group —CO(C1-C4)alk or a group —NHSO2—(C1-C4)alk; a group (C1-C4)alk, a group (C1-C4)alkoxy, a halogen, —COOH, —COO(C1-C4)alk, —CN, —CONR3R4, —NO2, —SO2NH2 or —NHSO2(C1-C4)alk;

Abstract: An electric heater assembly suitable for heating molten metal, the electric heater assembly having a sleeve comprised of a closed end suitable for immersing in the molten metal. The sleeve is fabricated from a composite material comprised of titanium alloy and having an outside surface to be exposed to the molten metal coated with a refractory resistant to attack by the molten metal having a sealant metal applied thereto; and an electric heater located in the sleeve in heat transfer relationship therewith.

Abstract: Compounds corresponding to general formula (I) in which R1, R2, R3, R4 and R5 each represent, independently of one another, a hydrogen or halogen atom or a nitro, amino, trifluoromethyl, trifluoromethoxy, cyano, hydroxy, (C1-C6)alkyl, (C1-C6)alkoxy or phenyl group, it also being possible for two of these substituents in adjacent positions together to represent a methylenedioxy group, and R6 represents a hydrogen atom or a (C1-C6)alkyl group. Application in therapeutics.

Abstract: A method of maintaining molten salt concentration in a low temperature electrolytic cell used for production of aluminum from alumina dissolved in a molten salt electrolyte contained in a cell free of frozen crust wherein volatile material is vented from the cell and contacted and captured on alumina being added to the cell. The captured volatile material is returned with alumina to cell to maintain the concentration of the molten salt.

Abstract: Compounds of the general formula (I) in which R1, R2, R3 and R4 each represent a hydrogen or halogen atom or a nitro, amino, trifluoromethyl, cyano, hydroxyl, alkyl or alkoxy group, X represents either a nitrogen atom, in which case Z represents a group of the formula C—R5 or a nitrogen atom, or a group of the formula C—R6, in which case Z represents a nitrogen atom, R5 and R6 each represent a hydrogen or halogen atom or a trifluoromethyl, cyano, hydroxyl, (C1-C6)alkyl or (C1-C6)alkoxy group, and R7 represents a hydrogen atom or a (C1-C6)alkyl group. Use in therapy.

Abstract: Two reference voltages and two differential receivers are used to detect low-to-high and high-to-low transitions on an input signal and set a received signal output. One reference voltage is set near but under the electrical high voltage level and the other is set near but above the electrical low voltage level. The reference voltage that is closest to the input signal is designated as the active reference voltage. When the input signal crosses the active reference voltage digital value of the received signal output is changed. When the input signal then crosses the inactive reference voltage, the inactive reference voltage is made the active reference voltage. A dead-time is then waited where input signal crossings of the active reference voltage are ignored. After the dead-time, input signal crossings of the active reference voltage will change the received signal output.

Abstract: A technique is provided for insulating a winding or coil for an electrical machine such as a motor. The coil is wound and placed in a taping station. Multiple layers of insulating tape are applied along an end region with leads bent back from the end region. The taping station permits the leads to be then placed over the insulated end region, and the main body region of the coil is similarly taped in a continuous uninterrupted manner. The tape wrap pitch may be varied along certain regions, where increased dielectric strength is desired. Following the insulating tape application, an armor tape may be applied over both the end region and the main region of the coil in a continuous uninterrupted manner. The coil can then be finished and assembled in a machine such as an electric motor stator.

Abstract: Methods and compositions are provided for the production of human manganese superoxide dismutase and a protocol for enhancing efficiency of expression. The gene encoding for human manganese superoxide dismutase was isolated and inserted into a vector in conjunction with a synthetic linker which provides for enhanced efficiency in translation. E. coli strain HB101 containing the plasmid Nco5AHSODm was deposited at the A.T.C.C. on Oct. 3, 1986 and given Accession No. 67191.

Abstract: Components designed for use in networked control and monitoring systems including dedicated memory objects which store data representative of the system, the component and the function of the component in the system. The component-specific information may include data indicating the physical location of the component in the system. The objects are reprogrammable to adapt to system changes. A system comprising the components allows the objects to be accessed via a data network. Controlled or monitored parameters of the components may thus be collected in association with the other data stored in the objects.

Abstract: A practically usable DNA detection method by a DNA hybridization method with the use of fluorescent resonance energy transfer wherein the background luminescence based on the luminescence of a donor and the direct excitation of an acceptor) affecting the sensitized luminescence of the acceptor is minimized so that a target DNA strand can be conveniently and very easily detected in a homogeneous solution. In this DNA detection method, a DNA is detected by the DNA hybridization method by using, as detection reagents, streptoavidin labeled with a fluorescent rare earth metal complex, a nucleic acid probe modified with biotin and a nucleic acid probe labeled with an organic cyanine pigment and taking advantage of florescent resonance energy transfer.

Abstract: The invention relates to novel and valuable intermediate compounds of the general formula (VIII) which can be used for the preparation of novel compounds comprising an antibacterial action, especially with a strong antibacterial action against helicobacter pylori, and pharmaceutically acceptable salts thereof. In the general formula (VIII) X is hydrogen or halogen, Y is hydrogen or a substituted or unsubstituted aralkyloxycarbonyl group having 8-19 carbon atoms, Z is hydrogen, a substituted aralkyloxycarbonyl group having 8-19 carbon atoms or a substituted alkoxycarbonyyl group having 2-19 carbon atoms, except that X, Y and Z are all hydrogen.

Abstract: An improved raster engine adapted to render video data from a frame buffer to one of a plurality of disparate displays is disclosed which comprises an integral bounded video signature analyzer, a hardware cursor apparatus supporting dual scanned displays, programmatic support for multiple disparate display types, multi-mode programmable hardware blinking, programmable multiple color depth digital display interface, and programmable matrix controlled grayscale generation.

Abstract: Filters and filter materials for removing microorganisms from a fluid are provided along with processes for using the same. The filters include a housing having an inlet and an outlet and a filter material disposed within the housing, wherein the filter material is formed at least in part from a plurality of filter particles having an activated coating with a lignosulfonate.

Abstract: Compositions, methods and kits for purifying, clarifying nutrifying and any combination thereof, contaminated drinking water, which contain a primary coagulant material and a bridging flocculent material. The levels and ratios of coagulant to flocculent preferably fall within certain ranges. Highly preferred compositions also contain one or more of a cationic coagulant aid, especially chitosan, a microbiocidal disinfectant, a water-soluble alkali, a water-insoluble silicate, and a food additive or nutrient source.

Abstract: The present invention provides a sound barrier system 10 including a sound barrier panel 20 having a face skin panel 30 held in spaced relation from a back skin panel 40 by a filler material 50. Each sound barrier panel 20 is provided with a tongue and groove design that permits panels 20 to be stacked in an interlocking fashion without fastening hardware.

Abstract: The invention relates to 2-butyl-5-(methanesulfonamido)benzofuran, its preparation and its use. This compound is a synthesis intermediate, in particular for the preparation of dronedarone.