Patents Represented by Attorney, Agent or Law Firm Alicia J. Hager
  • Patent number: 6475809
    Abstract: Protein arrays and protein-coated substrates for the parallel, in vitro screening of biomolecular activity are provided. Methods of using the protein-coated substrates and protein arrays are also disclosed. A plurality of different members of a single protein family may be immobilized on the protein-coated substrate or array. The protein-coated substrates and protein arrays are particularly useful in high-throughput drug screening and clinical diagnostics.
    Type: Grant
    Filed: May 12, 2000
    Date of Patent: November 5, 2002
    Assignee: Zyomyx, Incorporated
    Inventors: Peter Wagner, Dana Ault-Riche, Steffen Nock, Christian Itin
  • Patent number: 6475808
    Abstract: Protein arrays for the parallel, in vitro screening of biomolecular activity are provided. Methods of using the protein arrays are also disclosed. On the arrays, a plurality of different proteins, such as different members of a single protein family, are immobilized on one or more organic thinfilms on the substrate surface. The protein arrays are particularly useful in drug development, proteomics, and clinical diagnostics.
    Type: Grant
    Filed: July 14, 1999
    Date of Patent: November 5, 2002
    Assignee: Zyomyx, Incorporated
    Inventors: Peter Wagner, Dana Ault-Riche, Steffen Nock, Christian Itin
  • Patent number: 6406921
    Abstract: Protein arrays and protein-coated substrates for the parallel, in vitro screening of biomolecular activity are provided. Methods of using the protein-coated substrates and protein arrays are also disclosed. A plurality of different members of a single protein family may be immobilized on the protein-coated substrate or array. The protein-coated substrates and protein arrays are particularly useful in high-throughput drug screening and clinical diagnostics.
    Type: Grant
    Filed: July 14, 1998
    Date of Patent: June 18, 2002
    Assignee: Zyomyx, Incorporated
    Inventors: Peter Wagner, Dana Ault-Riche, Steffen Nock, Christian Itin
  • Patent number: 6365418
    Abstract: Arrays of protein-capture agents useful for the simultaneous detection of a plurality of proteins which are the expression products, or fragments thereof, of a cell or population of cells in an organism are provided. A variety of antibody arrays, in particular, are described. Methods of both making and using the arrays of protein-capture agents are also disclosed. The invention arrays are particularly useful for various proteomics applications including assessing patterns of protein expression and modification in cells.
    Type: Grant
    Filed: May 18, 2000
    Date of Patent: April 2, 2002
    Assignee: Zyomyx, Incorporated
    Inventors: Peter Wagner, Steffen Nock, Dana Ault-Riche, Christian Itin
  • Patent number: 6329209
    Abstract: Arrays of protein-capture agents useful for the simultaneous detection of a plurality of proteins which are the expression products, or fragments thereof, of a cell or population of cells in an organism are provided. A variety of antibody arrays, in particular, are described. Methods of both making and using the arrays of protein-capture agents are also disclosed. The invention arrays are particularly useful for various proteomics applications including assessing patterns of protein expression and modification in cells.
    Type: Grant
    Filed: July 14, 1999
    Date of Patent: December 11, 2001
    Assignee: Zyomyx, Incorporated
    Inventors: Peter Wagner, Steffen Nock, Dana Ault-Riche, Christian Itin