Patents Represented by Law Firm Amster & Rothstein
  • Method for removing Doppler angle ambiguity
    Patent number: 7591787
    Abstract: A method of measuring blood flow including several steps. In an initial step a first ultrasound beam is oriented in a direction substantially perpendicular to the direction of the blood flow to be measured. Next, the Doppler spectrum obtained from the backscattered echoes of said first ultrasound beam is measured. Subsequently, the ultrasound beam is reoriented so that the Doppler spectrum of the backscattered echoes of the ultrasound beam is substantially symmetrical around the zero frequency. The Doppler frequency of the backscattered echoes of a second ultrasound beam oriented at a fixed angle to the first ultrasound beam is then measured. Finally, the rate of blood flow is calculated based on the angle between the ultrasound beams and the measured Doppler frequency of the backscattered echoes of the second ultrasound beam.
    Type: Grant
    Filed: September 15, 2005
    Date of Patent: September 22, 2009
    Inventor: Piero Tortoli
  • Use of VEGF and homologues to treat neuron disorders
    Patent number: 7592314
    Abstract: The present invention relates to neurological and physiological dysfunction associated with neuron disorders. In particular, the invention relates to the involvement of vascular endothelial growth factor (VEGF) and homologues in the aetiology of motor neuron disorders. The invention further concerns a novel, mutant transgenic mouse (VEGFm/m) with a homozygous deletion in the hypoxia responsive element (HRE) of the VEGF promoter which alters the hypoxic upregulation of VEGF. These mice suffer severe adult onset muscle weakness due to progressive spinal motor neuron degeneration which is reminiscent of amyotrophic lateral sclerosis (ALS)—a fatal disorder with unknown aetiology. Furthermore, the neuropathy of these mice is not caused by vascular defects, but is due to defective VEGF-mediated survival signals to motor neurons.
    Type: Grant
    Filed: June 4, 2007
    Date of Patent: September 22, 2009
    Assignees: Viaams Interuniversitair Instituut voor Biotechnologie VZW, Life Sciences Research PartnersVZW
    Inventors: Peter Carmeliet, Désiré Collen, Bert Oosthuyse
  • Squirting toy
    Patent number: 7571837
    Abstract: A squirting toy is comprised of a cylindrical housing and a piston that slides within to force water into or out of the housing via a hole therein. The housing is encased within a polyethylene closed cell foam shell. The shell is non-absorbing, so that the foam remains buoyant and keeps the gun afloat indefinitely when left in water. The foam is soft, so that the gun is not a safety hazard when left floating in a swimming pool.
    Type: Grant
    Filed: September 25, 2007
    Date of Patent: August 11, 2009
    Assignee: Prime Time Toys, Ltd.
    Inventor: Boguslaw Orlowski
  • Method, apparatus and kit for demonstrating the use of absorbent products
    Patent number: 7566222
    Abstract: An apparatus is provided for demonstrating an absorbent product. The apparatus includes a torso-shaped manikin on which an absorbent product can be donned. An inlet is positioned on the manikin to receive synthetic urine, a first outlet is positioned on the manikin to correspond to male anatomy, and a second outlet is positioned on the manikin to correspond to female anatomy. A passageway is positioned in the manikin to direct synthetic urine from the inlet toward the first and second outlets. A method and kit are also provided for demonstrating the absorbent product.
    Type: Grant
    Filed: November 12, 2004
    Date of Patent: July 28, 2009
    Assignee: First Quality Retail Services, LLC
    Inventor: Thomas Harkin
  • Projectile and method for sealing a projectile in a barrel
    Patent number: 7565761
    Abstract: A barrel assembly for a weapon, said barrel assembly including a barrel; a plurality of projectile assemblies axially disposed in end to end abutting relationship within said barrel for operative sealing engagement with the bore of the barrel, each projectile including a projectile head and an integral cylindrical spacer portion extending axially and rearwardly from said projectile head; discrete propellant charges accommodated within said cylindrical spacer portion for propelling respective projectile assemblies sequentially through the muzzle of the barrel; ignition means for igniting said discrete propellant charges; and control means for selectively and sequentially actuating the ignition means.
    Type: Grant
    Filed: June 20, 2007
    Date of Patent: July 28, 2009
    Assignee: Metal Storm Limited
    Inventor: James Michael O'Dwyer
  • 5h-pyrrolo[3,2-D] pyrimidine inhibitors of nucleoside phosphorylases and nucleosidases
    Patent number: 7553839
    Abstract: The present invention relates to compounds of the general formula (I) which are inhibitors of purine muclioside phosphorylases (PNP), purine phosphoribosyltransferases (PPRT), 5?-methylthioadenosine phosphorylases (MTAP), 5?-methylthioadenosine mucliosidases (MTAN) and/or nucleoside hydrolases (NH). The invention also relates to the use of these compounds in the treatment of diseases and infections including cancer, bacterial infections, protozoal infections, and T-cell mediated disease and to pharmaceutical compositions containing the compounds.
    Type: Grant
    Filed: August 21, 2003
    Date of Patent: June 30, 2009
    Assignees: Industrial Research Limited, Albert Einstein College of Medicine of Yeshiva University
    Inventors: Gary Brian Evans, Richard Hubert Furneaux, Dirk Henning Lenz, Vern L. Schramm, Peter Charles Tyler, Olga Vladimirovna Zubkova
  • Reversible nipple adapter
    Patent number: 7552831
    Abstract: A nipple adapter including a nipple having a first outer sealing flange and a second outer sealing flange, and a cylindrical nipple housing. The nipple housing includes an inner annular wall that defines a bore extending axially through the housing, an annular flange disposed on the inner annular wall, a first thread extending from the annular flange to a first axial end of the nipple housing, and a second thread extending from the annular flange to a second axial end of the nipple housing, the first thread having a pitch that differs from that of the second thread. The nipple is reversibly disposed within the nipple housing such that the annular flange is disposed between the first and second outer sealing flanges and the first and second threads are alternatively exposed for mating with corresponding threads of a variety of water bottles.
    Type: Grant
    Filed: November 3, 2005
    Date of Patent: June 30, 2009
    Inventor: Morris Catton
  • Dynamic, adjustable orthopedic device
    Patent number: 7549968
    Abstract: Provided are dynamic, adjustable orthopedic devices for providing support to the spine of a vertebrate. Also provided are methods of supporting the spinal column of a vertebrate using the device.
    Type: Grant
    Filed: December 29, 2005
    Date of Patent: June 23, 2009
    Inventor: Milun Cojbasic
  • Windshield wiper blade
    Patent number: D593480
    Type: Grant
    Filed: September 9, 2008
    Date of Patent: June 2, 2009
    Inventor: In-Kyu Kim
  • Shower head
    Patent number: D594090
    Type: Grant
    Filed: September 9, 2008
    Date of Patent: June 9, 2009
    Assignee: Alpha-Omega Group Limited
    Inventor: Hing Fai Tse
  • Windshield wiper blade
    Patent number: D594805
    Type: Grant
    Filed: September 9, 2008
    Date of Patent: June 23, 2009
    Inventor: In-Kyu Kim
  • Windshield wiper blade
    Patent number: D594806
    Type: Grant
    Filed: September 9, 2008
    Date of Patent: June 23, 2009
    Inventor: In-Kyu Kim
  • Wind and solar-powered light post
    Patent number: D595885
    Type: Grant
    Filed: January 21, 2009
    Date of Patent: July 7, 2009
    Assignee: Duggal Dimensions LLC
    Inventors: Paul D. Daidone, Ryan Reitbauer
  • Tumbler
    Patent number: D596462
    Type: Grant
    Filed: October 18, 2006
    Date of Patent: July 21, 2009
    Inventors: Thierry Serruya, David Putterman
  • Shower head
    Patent number: D598069
    Type: Grant
    Filed: September 9, 2008
    Date of Patent: August 11, 2009
    Assignee: Alpha-Omega Group Limited
    Inventor: Hing Fai Tse
  • Windshield wiper blade
    Patent number: D598359
    Type: Grant
    Filed: September 9, 2008
    Date of Patent: August 18, 2009
    Inventor: In-Kyu Kim
  • Bollard
    Patent number: D599913
    Type: Grant
    Filed: July 30, 2008
    Date of Patent: September 8, 2009
    Assignee: Island Global Yachting Ltd.
    Inventor: Oscar Juan Jose Siches
  • Bollard
    Patent number: D599914
    Type: Grant
    Filed: July 30, 2008
    Date of Patent: September 8, 2009
    Assignee: Island Global Yachting Ltd.
    Inventor: Oscar Juan Jose Siches
  • All in one adaptor wiper blade
    Patent number: D601077
    Type: Grant
    Filed: September 10, 2008
    Date of Patent: September 29, 2009
    Inventor: In-Kyu Kim
  • Shower head
    Patent number: D601222
    Type: Grant
    Filed: September 9, 2008
    Date of Patent: September 29, 2009
    Assignee: Alpha-Omega Group Limited
    Inventor: Hing Fai Tse