Patents Represented by Attorney Andrea Dorigo

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  • Glutamate aggrecanase inhibitors
    Patent number: 7553873
    Abstract: The present invention relates to modulators of metalloproteinase activity.
    Type: Grant
    Filed: July 11, 2006
    Date of Patent: June 30, 2009
    Assignee: Wyeth
    Inventors: Phaik-Eng Sum, Jerauld Stanley Skotnicki, Steve Yik-Kai Tam, Tarek Suhayl Mansour, David Brian How, Joshua James Sabatini, Jason Shaoyun Xiang, Eric Feyfant
  • Methods for preparing glutamic acid derivatives
    Patent number: 7541485
    Abstract: The present invention relates to novel methods for the preparation of glutamic acid derivatives and intermediates thereof, and such compounds prepared by the novel methods.
    Type: Grant
    Filed: July 11, 2006
    Date of Patent: June 2, 2009
    Assignee: Wyeth
    Inventors: Ronald S. Michalak, Joseph Zeldis, Mel Jennings, David M. Blum, Timothy Doyle
  • Glucuronide metabolites and epimers thereof of tigecycline
    Patent number: 7534766
    Abstract: A glucuronide metabolite of tigecycline, and its corresponding epimer, have been identified in humans treated with tigecycline. Mass spectral data have been used to identify these structures.
    Type: Grant
    Filed: November 2, 2005
    Date of Patent: May 19, 2009
    Assignee: Wyeth
    Inventors: Ronald A. Jordan, William DeMaio, Matthew Hoffmann
  • Amino-5-(6-membered)heteroarylimidazolone compounds and the use thereof for ?-secretase modulation
    Patent number: 7452885
    Abstract: The present invention provides a 2-amino-5-heteroaryl-5-phenylimidazolone compound of formula I The present invention also provides methods for the use thereof to inhibit ?-secretase (BACE) and treat ?-amyloid deposits and neurofibrillary tangles.
    Type: Grant
    Filed: June 29, 2006
    Date of Patent: November 18, 2008
    Assignee: Wyeth
    Inventors: Ping Zhou, Michael Sotirios Malamas, Yanfang Li, Albert Jean Robichaud, Dominick Anthony Quagliato