Patents Represented by Attorney, Agent or Law Firm Andrea E. Dorigo
  • Determination of antibiotic concentration in bone
    Patent number: 7427507
    Abstract: A method of determining the concentration of antibiotic in bone comprising crushing the bone, adding a stabilizing agent to the bone, homogenizing the bone in an extraction solvent to obtain a homogenous suspension, and analyzing the suspension supernatant to determine the concentration of antibiotic in bone.
    Type: Grant
    Filed: May 2, 2007
    Date of Patent: September 23, 2008
    Assignee: Wyeth
    Inventors: Allena J. Ji, James P. Saunders
  • Pharmaceutically active compounds and methods of use
    Patent number: 7423059
    Abstract: The present invention relates to certain imine-substituted heterocyclic compounds, and methods of treatment and pharmaceutical compositions that utilize or comprise one or more such compounds. Compounds of the invention are particularly useful for the treatment or prophylaxis of neurological injury and neurodegenerative disorders.
    Type: Grant
    Filed: June 28, 2004
    Date of Patent: September 9, 2008
    Assignee: Wyeth
    Inventors: Graham J. Durant, Michael Maillard, Jun Qing Guo
  • Corticotropin releasing factor antagonists
    Patent number: 6833378
    Abstract: Corticotropin-releasing factor (CRF) antagonists having the formulae wherein the dashed lines, A, B, Y, Z, G, R3, R4, R5, R6, R16 and R17 are as defined in the application, and processes for preparing them. These compounds and their pharmaceutically acceptable salts are useful in the treatment disorders including CNS and stress-related disorders.
    Type: Grant
    Filed: January 17, 2001
    Date of Patent: December 21, 2004
    Assignee: Pfizer Inc
    Inventor: Yuhpyng L. Chen
  • Use of corticotropin releasing factor antagonists and related compositions
    Patent number: 6777404
    Abstract: The present invention relates to compositions and methods of achieving a therapeutic effect including, the treatment or prevention of Syndrome X in an animal, preferably a mammal including a human subject or a companion animal, using a corticotropin releasing factor (CRF) antagonist alone or together with a glucocorticoid receptor antagonist.
    Type: Grant
    Filed: April 15, 2003
    Date of Patent: August 17, 2004
    Assignee: Pfizer Inc
    Inventors: Ernest S. Hamanaka, Yuhpyng Liang Chen
  • Treatments for restless legs syndrome
    Patent number: 6716854
    Abstract: The invention provides methods and use of heterocyclic amines, and phenylazacycloalkane compounds, and their pharmacologically acceptable salts for the treatment of Restless Legs Syndrome (RLS).
    Type: Grant
    Filed: April 25, 2003
    Date of Patent: April 6, 2004
    Assignee: Pfizer, Inc.
    Inventors: Sylvia McBrinn, Richard Wayne Anderson