Patents Represented by Attorney, Agent or Law Firm Andrew M. Solomon
  • Patent number: 6624160
    Abstract: This invention provides compounds of formula I; which are useful as antiviral agents.
    Type: Grant
    Filed: March 15, 2001
    Date of Patent: September 23, 2003
    Assignee: Pharmacia & Upjohn Co.
    Inventors: Valerie A. Vaillancourt, Scott D. Larsen, Sajiv K. Nair
  • Patent number: 6559145
    Abstract: The present invention provides a compound of formula I which is useful as antiviral agents, in particular, as agents against viruses of the herpes family.
    Type: Grant
    Filed: June 22, 2001
    Date of Patent: May 6, 2003
    Assignee: Pharmacia & Upjohn Company
    Inventors: Fred L. Ciske, Michael J. Genin, Byung Hyun Lee, Mark E. Schnute, Valerie A. Vaillancourt
  • Patent number: 6458788
    Abstract: Certain novel 4-hydroxycinnoline-3-carboxyamides. The compounds are particularly effective in the treatment or prevention of viral infections, particularly infections caused by herpes viruses including herpes simplex virus types 1 and 2, human herpes virus types 6, 7 and 8, varicello zoster virus, human cytomegalovirus or Epstein-Barr virus.
    Type: Grant
    Filed: March 15, 2001
    Date of Patent: October 1, 2002
    Assignee: Pharmacia & Upjohn Company
    Inventors: Valerie A. Vaillancourt, Scott D. Larsen, Sajiv K. Nair
  • Patent number: 6451811
    Abstract: The resent invention provides a compound of Formula III which is useful for the treatment or prevention of herpes viruses.
    Type: Grant
    Filed: March 15, 2001
    Date of Patent: September 17, 2002
    Assignee: Pharmacia & Upjohn Company
    Inventors: Valerie A. Vaillancourt, Atli Thorarensen
  • Patent number: 6451365
    Abstract: An antibacterial composition comprising: (a) a first component including at least one gram positive bacteristatic or bactericidal compound selected from the group consisting of lantibiotics, pediocin, and lacticin class bacteriocins, and lytic enzymes; and (b) a second component including at least one compound selected from the group consisting of hops acids and hops acid derivatives, and the method of applying said composition to the surfaces of solid food.
    Type: Grant
    Filed: July 14, 2000
    Date of Patent: September 17, 2002
    Assignee: Rhodia Inc.
    Inventors: William King, Xintian Ming
  • Patent number: 6413958
    Abstract: Certain novel 4-hydroxy-1,8-naphthyridine-3-carboxyamides. The compounds are effective in the treatment or prevention of viral infections, particularly viral infections caused by herpes simplex viruses types 1 and 2, human herpes viruses types 6, 7 and 8, varicello zoster viruses, human cytomegaloviruses and Epstein-Barr viruses.
    Type: Grant
    Filed: March 15, 2001
    Date of Patent: July 2, 2002
    Assignee: Pharmacia & Upjohn Company
    Inventor: Valerie A. Vaillancourt
  • Patent number: 6391876
    Abstract: This invention relates to the use of reboxetine in the treatment of Obsessive Compulsive Disorders and Panic Disorders.
    Type: Grant
    Filed: October 19, 2000
    Date of Patent: May 21, 2002
    Assignee: Pharmacia and Upjohn Company
    Inventors: Adriana Dubini, John Michael McCall, Duncan Paul Taylor, Philip F. Von Voigtlander, Erik Ho Fong Wong
  • Patent number: 6235907
    Abstract: This invention discloses and claims novel intermediates and procedures for the synthesis of camptothecin derivatives, such as irinotecan, and other compounds related to the synthesis of CPT-11. Related procedures and compounds are also disclosed, such as a novel method of making mappicine.
    Type: Grant
    Filed: February 22, 2000
    Date of Patent: May 22, 2001
    Assignee: Pharmacia & Upjohn Company
    Inventors: Kevin E. Henegar, John C. Sih
  • Patent number: 6228397
    Abstract: The present invention provides a pharmaceutical composition which is substantially free of unpleasant tastes and orally administrable which comprises: (a) an active medicament, (b) an inner coating layer comprising an oil substance having a melting point at a range of from about 50° C. to about 100° C., (c) an outer coating layer comprising at least a polymeric substance.
    Type: Grant
    Filed: August 25, 1998
    Date of Patent: May 8, 2001
    Assignee: Pharmacia & Upjohn COmpany
    Inventors: Robert W. Shen, Gerald A. Walter
  • Patent number: 6191143
    Abstract: The present invention provides a method of topically administering antimicrobial agents such as premafloxacin, premafloxacin-like compound, premafloxacin ester, ciprofloxacin, enrofloxacin, cefquinome, cefpodoxime, gentamicin or erythromycin for the treatment of systemic bacterial diseases in mammals.
    Type: Grant
    Filed: March 17, 1999
    Date of Patent: February 20, 2001
    Assignee: Pharmacia & Upjohn Company
    Inventors: Jeffrey L. Watts, Randall G. Stehle
  • Patent number: 6187818
    Abstract: This invention comprises new formulations and methods of preparing a new formulations of prostaglandins and in particular dinoprost tromethamine, where the pH of the formulation is adjusted to between about 5.5-7.5 and where the the concentration of benzyl alcohol is between about 1.2 to 2.0 mg/ml.
    Type: Grant
    Filed: June 17, 1998
    Date of Patent: February 13, 2001
    Assignee: Pharmacia & Upjohn Company
    Inventor: Robert G. Re
  • Patent number: 6171388
    Abstract: A composition of matter comprising (a) gypsum (CaSO4 . 2H2O); (b) one or more naturally occurring or synthetic latex polymers; and (c) one or more nonionic surfactants; wherein said composition of matter has a density less than 0.64 g/cm3 and wherein wallboard produced from said composition of matter satisfies the criteria of ASTM Methods C-36 and C-473 is provided.
    Type: Grant
    Filed: March 11, 1999
    Date of Patent: January 9, 2001
    Assignee: Rhodia Inc.
    Inventor: Richard M. Jobbins
  • Patent number: 6146263
    Abstract: An apparatus is provided for cleaning poultry carcasses having a cavity. A plurality of cleaning heads are spaced about a sprayer carousel that is rotatably mounted upon a vertical shaft. The cleaning heads are mounted upon a plurality of vertically oriented guide rails which are spaced about the sprayer carousel. A circumferential cam is fixedly connected to the vertical shaft inside the sprayer carousel. A cam follower connected to each cleaning head follows the profile of the cam, displacing the cleaning head vertically along the guide rails. A conveyor transports the carcasses sequentially into and out of engagement with the sprayer carousel and an indexing member maintains each of the carcasses in alignment with one of the cleaning heads. In response to relative movement between the fixed cam and the rotatable sprayer carousel the cam follower of each cleaning head follows the circumferential profile of the cam.
    Type: Grant
    Filed: November 14, 1996
    Date of Patent: November 14, 2000
    Assignee: Rhodia Inc.
    Inventors: Charles R. Mostoller, Fritz Norbury
  • Patent number: 6140398
    Abstract: A novel composition of matter comprising the reaction product of a phosphoryl compound, a salicylic acid derivative, and an organic compound containing two groups having hydroxyl functionality is provided. This composition has utility as a fire retardant chemical.
    Type: Grant
    Filed: July 7, 1999
    Date of Patent: October 31, 2000
    Assignee: Rhodia Inc.
    Inventor: Johnson D. Koola
  • Patent number: 6127494
    Abstract: A process for forming a hydrophobically modified water soluble or water dispersible polymer by utilizing a micellar polymerization technique comprising the steps of: (1) providing a reaction medium including one or more water soluble or water dispersible monomers and one or more surface active agents or protective colloids; (2) incrementally adding one or more ethylenically unsaturated monomers having hydrophobic properties to said reaction medium; (3) initiating polymerization of said one or more water soluble or water dispersible monomers with said one or more ethylenically unsaturated monomers having hydrophobic properties; and (4) continuing polymerization of said one or more water soluble or water dispersible monomers with said one or more ethylenically unsaturated monomers having hydrophobic properties while incrementally adding said one or more ethylenically unsaturated monomers having hydrophobic properties to said reaction medium is provided.
    Type: Grant
    Filed: July 14, 1998
    Date of Patent: October 3, 2000
    Assignee: Rhodia Chimie
    Inventor: Eric H. Larson
  • Patent number: 6124306
    Abstract: The subject invention relates to pyrimidine-thioalkyl and alkylether compounds of Formula I ##STR1## and pyrimidine-thioalkyl and alkylethers of Formula I, where R.sub.4 is selected from the group consisting of --H or --NR.sub.15 R.sub.16 where R.sub.15 is --H and R.sub.16 is --H, C.sub.1 -C.sub.6 alkyl, --NH.sub.2 or R.sub.15 and R.sub.16 taken together with the --N form 1-pyrrolidino, 1-morpholino or 1-piperidino; andR.sub.6 is --S--C.sub.1-6 alkyl (preferably --SCH.sub.3);The compounds of Formula I are useful in the treatment of individuals who are HIV positive.
    Type: Grant
    Filed: September 21, 1998
    Date of Patent: September 26, 2000
    Assignee: Pharmacia & Upjohn Company
    Inventors: Joel Morris, Wade J. Adams, Janice M. Friis, Donn G. Wishka
  • Patent number: 6123981
    Abstract: Phosphate is recovered from waste. Trialkali metal orthophosphate used to reduce, remove or retard bacterial contamination during raw meat slaughter including poultry, fish and shellfish and red meat evisceration is recovered from an aqueous waste and recycled as a food additive for animal feed. The waste water containing the phosphate can be collected and mixed with offal during processing of the offal or may be concentrated and blended with the offal as feed for animals or may be reacted with an alkaline earth metal salt and concentrated and used as a calcium and phosphate supplement for animal feed. Trisodium orthophosphate is reacted with calcium chloride and the resulting precipitate removed from the aqueous stream by filtration or centrifugation or other means for separation. The precipitate is then added to offal during processing for animal feed or dried sterilized and sold as an animal feed mineral supplement.
    Type: Grant
    Filed: October 27, 1992
    Date of Patent: September 26, 2000
    Assignee: Rhodia Inc.
    Inventors: Fredric Grant Bender, John Toczek, William E. Swartz
  • Patent number: 6121451
    Abstract: This invention relates to intermediates and processes for the synthesis of camtothecin derivatives, such as irinotecan. Related procedures and compounds are disclosed, such as a method of making mappicine.
    Type: Grant
    Filed: October 2, 1997
    Date of Patent: September 19, 2000
    Assignee: Pharmacia & Upjohn Company
    Inventors: Kevin E. Henegar, John C. Sih
  • Patent number: 6113809
    Abstract: Increased foam quality and resistance to hydrocarbon defoaming for foams used in well boring and stimulation processes as well as secondary and tertiary oil recovery is obtained using imidazoline-based amphoacetates of higher purity, containing essentially negligible amounts of unalkylated amido amines, lower amounts of glycolic acid salts and monochloroacetate salts.The higher purity amphoacetates can be obtained via processes utilizing precise pH control during the reaction of imidazoline, or its open-chain derivatives, with alkylating agents, e.g. sodium monochloroacetate. These higher-purity amphoacetates contain essentially fully alkylated products and lower amounts of glycolic acid derivatives, even though a ratio of monohaloalkylate to substituted imidazoline, or its open-ring derivative, of less than 1.5:1.0 and close to 1.0:1.0 is used.
    Type: Grant
    Filed: October 22, 1996
    Date of Patent: September 5, 2000
    Assignee: Rhodia Inc.
    Inventors: David Josehph Dino, Anthony Homack
  • Patent number: 6090820
    Abstract: A compound of structural Formula I or II which is useful for treating microbial infections in humans or other warm-blooded animals, or pharmaceultically acceptable salts thereof as defined herein.
    Type: Grant
    Filed: November 7, 1997
    Date of Patent: July 18, 2000
    Assignee: Pharmacia & Upjohn Company
    Inventors: Michael Robert Barbachyn, Steven Joseph Brickner, Douglas K. Hutchinson