Abstract: An apparatus and a process useful for producing patterned gelatin ribbons for forming patterned soft gelatin capsules are disclosed. The apparatus and process use multiple spreader boxes to form a wide variety of possible patterns.

Abstract: In one embodiment, this invention relates to a pharmaceutical composition for oral administration consisting essentially of a gelatin at a concentration up to 5% by weight as a carrier, a solvent, and, as an active ingredient, a dopamine agonist. Alternatively, the invention relates to a composition that takes the form of a solid, unitary fast-dispersing dosage form comprised of a network of an active ingredient after and a water-soluble or water dispersible matrix forming agent or carrier which is inert towards the active ingredient after subliming solvent from the composition in the solid state. The dosage is designed to completely disintegrate within 1 to 30 seconds of being placed in the oral cavity. Compositions which further comprise an anti-emetic and/or an opioid antagonist are also provided herein.

Abstract: A cold pack 10 made in accordance with the principles of the present invention includes a container 18. Disposed within the container 18 is a first endotherm-producing chemical 15. Also disposed within the container 18 is a solvent packet 13 and a chemical packet 11. Second endotherm-producing chemical 43 is disposed in the chemical packet 11. First endotherm-producing chemical 15, the solvent packet 13 and the chemical packet 11 are collectively components of the cold pack. Preferably the container 18 is sealed so as to surround and encase the components of the cold pack 10. The first endotherm-producing chemical 15 and the second endotherm-producing chemical 43 are selected to be different. Both the first endotherm-producing chemical 15 and the second endotherm-producing chemical 43 may be selected from among those compounds with a positive enthalpy of solution (&Dgr;sol/H°, kJ/mol) and which produce a reduced temperature of solution that is greater than 10° F.

Abstract: A water-resistant, film-forming topical antimicrobial composition, removable by high pH solution, made in accordance with the principles of the present invention includes a polyvinyl lactam, a broad spectrum antimicrobial agent, a copolymer of polyacrylate/polyoctylacrylamide, a pH sensitive acrylic polymer, and an alcohol. Preferably, the polyvinyl lactam is polyvinyl pyrrolidone. The preferred broad spectrum antimicrobial agent is iodine which is preferably complexed to the polyvinyl pyrrolidone. A process for making the film-forming topical antimicrobial composition is also provided.