Patents Represented by Attorney Angela Foster, Esq.

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  • Development of a simple animal model for infection by viruses and other obligate intracellular parasites
    Patent number: 7932430
    Abstract: The present invention provides methods for studying pathogenesis of mammalian viruses. In particular, the present invention provides a nonhuman animal model system for studying disease mechanisms wherein the nonhuman animal model is infected with an animal virus. In a preferred embodiment the animal model is C. elegans and the animal virus is vesicular stomatitis virus (VSV).
    Type: Grant
    Filed: November 1, 2007
    Date of Patent: April 26, 2011
    Assignee: Board of Trustees of the University of Arkansas
    Inventors: Marie Chow, Courtney Wilkins, Khaled Machaca
  • Mitogen-activated protein kinase and method of use to enhance biotic and abiotic stress tolerance in plants
    Patent number: 7345219
    Abstract: The present invention relates to the mitogen-activated protein kinase called MAPK5. The rice MAPK5 gene, its protein and kinase activity were induced by abscisic acid, pathogen infection, wounding, drought, salt and cold temperature. However, suppression of MAPK5 expression and kinase activity in dsRNAi transgenic plants resulted in constitutive expression of pathogenesis-related genes such as PR-1 and PR-10 but enhanced resistance to fungal and bacterial pathogens. In contrast, overexpressed transgenic lines exhibited elevated MAPK5 kinase activity and increased tolerance to drought, salt and cold stresses. This invention provides methods for increasing tolerance to abiotic and biotic stress in plant using MAPK5.
    Type: Grant
    Filed: January 31, 2004
    Date of Patent: March 18, 2008
    Assignee: The Board of Trustees for the University of Arkansas
    Inventors: Yinong Yang, Lizhong Xiong
  • Method of detecting disease conditions in infected with animal virus
    Patent number: 7326528
    Abstract: The present invention provides methods for studying pathogenesis of mammalian viruses. In particular, the present invention provides a nonhuman animal model system for studying disease mechanism wherein the nonhuman animal model is infected with an animal virus. In a preferred embodiment, the animal model is C. elegans and the animal virus is vesicular stomatitis virus (VSV).
    Type: Grant
    Filed: December 22, 2003
    Date of Patent: February 5, 2008
    Assignee: Board of Trustees of the University of Arkansas
    Inventors: Marie Chow, Courtney Wilkins, Khaled Machaca
  • Organic acids incorporated edible antimicrobial films
    Patent number: 7160580
    Abstract: The present invention provides an edible film and film solution comprising incorporated organic acids; protein and glycerol useful for coating raw whole fruit, fresh cut fruit, vegetables, meat, poultry, seafood, cereals, nuts, etc. Moreover, the edible films of the present invention can inhibit pathogen growth including Listeria monocytogens, Salmonella gaminara and E. coli 0157:H7. In a preferred embodiment, the edible film comprises 0.9% glycerol; 10% soy protein; and 2.6% malic acid. The present invention also provides a method for coating comestible products with edible films without masking the color but increasing the shelf-life.
    Type: Grant
    Filed: September 8, 2003
    Date of Patent: January 9, 2007
    Assignee: The Board of Trustees for the University of Arkansas
    Inventors: Navam S. Hettiarachchy, Eswaranandam Satchithanandam
  • Molecular diagnosis of atypical mycobacterial infections
    Patent number: 7074568
    Abstract: The present invention provides methods for diagnosing mycobacteria other than tuberculosis (MOTT) infections in patients comprising amplifying the internal transcribed spacer sequence (ITSS) of 16S-23S rDNA of MOTT with primers that amplify MOTT but not Mycobacteria Tuberculosis (MTB). The present invention also provides a method for differentiating between MOTT and MTB infections comprising amplifying MOTT with primers that amplify MOTT but not MTB; amplifying MTB with primers that amplify MTB but not MOTT; and detecting approximately 130 base pair product indicative of MOTT and approximately 180 base pair product indicative of MTB.
    Type: Grant
    Filed: October 25, 2003
    Date of Patent: July 11, 2006
    Assignee: Board of Trustees of the University of Arkansas
    Inventor: Kunapuli T. Madhusudhan