Patents Represented by Attorney Anita Foley, Hoag & Eliot, LLP Varma

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  • D-type cyclins and uses related thereto
    Patent number: 5998582
    Abstract: A novel class of cyclins, referred to as D-type cyclins, of mammalian origin, particularly human origin, DNA and RNA encoding the novel cyclins, and a method of identifying other D-type and non-D type cyclins. Also disclosed are a method of detecting an increased level of a D-type cyclin and a method of inhibiting cell division by interfering with formation of the protein kinase-D type cyclin complex essential for cell cycle start.
    Type: Grant
    Filed: May 19, 1994
    Date of Patent: December 7, 1999
    Assignee: Cold Spring Harbor Laboratory
    Inventor: David H. Beach
  • Assays and reagents for identifying modulators of cdc25-mediated mitotic activation
    Patent number: 5861249
    Abstract: The present invention makes available assays and reagents for identifying agents which can be used to modulate at least one proliferation, differentiation and cell death by apoptosis.
    Type: Grant
    Filed: April 23, 1996
    Date of Patent: January 19, 1999
    Assignee: Cold Spring Harbor Laboratory
    Inventors: David H. Beach, Konstantin Galaktionov