Abstract: The invention relates to piperazine derivatives, to processes for their preparation, to pharmaceutical compositions containing them, and to their medical use. The novel compounds are antagonists of tachykinins, including substance P and other neurokinins.
Type:
Grant
Filed:
October 5, 2004
Date of Patent:
November 13, 2007
Assignee:
SmithKline Beecham Corporation
Inventors:
Giuseppe Alvaro, Romano DiFabio, Riccardo Giovannini, Giuseppe Guercio, Yves St-Denis, Antonella Ursini