Abstract: A syringe that can be positively pressurized via a one-way valve and illustrated by a pressure indicator is designed to be used with an epidural needle to identify epidural space and to protect the dura being punctured when a loss of positive pressure occurs. The inventive syringe housing having a plunger with a longitudinal bore for pressurization is connected to a pressure chamber via the one-way valve allowing air flow only into the pressurization chamber from the syringe housing. A needle is air-tightly connected to the pressurization chamber with a needle connecting device. A pressure indicator connected to the pressurization chamber objectively indicates the loss of positive pressure when the needle enters the epidural space. The positively pressurized air from the needle deflects the dura away from the needle tip and prevents dural puncture. Methods for detecting the epidural space and deflecting the dura using this inventive syringe are also provided.