Patents Represented by Attorney Arnold & Porter LLP
  • Patent number: 8350008
    Abstract: Wnt-1-Induced Secreted Proteins (WISPs) are provided, whose genes are induced at least by Wnt-1. Also provided are nucleic acid molecules encoding those polypeptides, as well as vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides, and methods for producing the polypeptides.
    Type: Grant
    Filed: May 26, 2011
    Date of Patent: January 8, 2013
    Assignee: Genentech, Inc.
    Inventors: David Botstein, Robert L. Cohen, Audrey D. Goddard, Austin L. Gurney, Kenneth J. Hillan, David A. Lawrence, Arnold J. Levine, Diane Pennica, Margaret Ann Roy, William I. Wood
  • Patent number: 8338132
    Abstract: The present invention is directed to novel polypeptides having sequence identity with IL-17, IL-17 receptors and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided herein are methods for treating degenerative cartilaginous disorders and other inflammatory diseases.
    Type: Grant
    Filed: March 27, 2009
    Date of Patent: December 25, 2012
    Assignee: Genentech, Inc.
    Inventors: Jian Chen, Ellen Filvaroff, Sherman Fong, Audrey Goddard, Paul Godowski, J. Christopher Grimaldi, Austin Gurney, Hanzhong Li, Kenneth Hillan, Sarah G. Hymowitz, Daniel Tumas, Melissa A. Starovasnik, Menno VanLookeren, Richard Vandlen, Colin Watanabe, P. Mickey Williams, William I. Wood, Daniel Yansura
  • Patent number: 8337485
    Abstract: The present invention relates to the regeneration, reconstruction, repair, augmentation or replacement of organs or tissue structures using scaffolds and autologous cells that are not derived from such organs or tissues.
    Type: Grant
    Filed: November 4, 2009
    Date of Patent: December 25, 2012
    Assignee: Tengion, Inc.
    Inventors: John W. Ludlow, Manuel J. Jayo, Joydeep Basu, Timothy A. Bertram, Christopher W. Genheimer, Kelly I. Guthrie, Roger M. Ilagan, Deepak Jain, Oluwatoyin A. Knight, Richard Payne, Sarah F. Quinlan, H. Scott Rapoport, Namrata D. Sangha
  • Patent number: 8338665
    Abstract: Methods of, and compositions for, assembling one or more transcription units in a genome without a linked selectable marker or other unwanted transcription unit are provided. Also provided methods of, and compositions for, assembling one or more transcription units in a genome with a reduced frequency of vector backbone.
    Type: Grant
    Filed: July 16, 2009
    Date of Patent: December 25, 2012
    Assignee: Monsanto Technology LLC
    Inventors: Larry Gilbertson, Susan Jane Johnson
  • Patent number: 8333964
    Abstract: The present application describes the use of ErbB antagonist, especially ErbB2 antibodies such as rhuMAb 2C4, for treating pain.
    Type: Grant
    Filed: November 29, 2010
    Date of Patent: December 18, 2012
    Assignee: Genentech, Inc.
    Inventor: David B. Agus
  • Patent number: 8329172
    Abstract: New combined therapeutic regimens for treatment of B-cell lymphomas are disclosed which comprise in particular administration of anti-CD20 antibodies to patients having low-, intermediate- or high-grade non-Hodgkins lymphomas.
    Type: Grant
    Filed: August 18, 2007
    Date of Patent: December 11, 2012
    Assignee: Biogen Idec
    Inventor: Antonio J. Grillo-López
  • Patent number: 8322918
    Abstract: The invention relates to a method for testing of a tempering apparatus, wherein the method comprises the following steps: starting of the method; operation of at least said first tempering device for the duration of at least one first period from at least one first time; detection of at least one measurement temperature from said at least one first temperature measurement device, which is assigned to said first tempering device, at least at a second time; determining at least one first testing quantity of the tempering apparatus by using said at least one measurement temperature; and comparison of said first testing quantity with one reference quantity.
    Type: Grant
    Filed: August 3, 2009
    Date of Patent: December 4, 2012
    Assignee: Eppendorf AG
    Inventors: Lutz Timmann, Vinh Duong, Stefan Roth, Thomas Uschkureit, Jurgen Koeppel, Thomas Buck, Michael Wild
  • Patent number: 8318705
    Abstract: The invention relates to nitroso derivatives including carboxylic acid and phosphoric acid esters of hydroxy nitroso compounds that donate nitroxyl (HNO) under physiological conditions. The compounds and compositions of the invention are useful in treating and/or preventing the onset and/or development of diseases or conditions that are responsive to nitroxyl therapy, including heart failure, ischemia/reperfusion injury and cancer.
    Type: Grant
    Filed: May 7, 2009
    Date of Patent: November 27, 2012
    Assignee: Cardioxyl Pharmaceuticals, Inc.
    Inventors: Lisa M. Frost, Stephen M. Courtney, Frederick A. Brookfield, Vincent J. Kalish
  • Patent number: 8318436
    Abstract: The present invention provides a method and compositions for high throughput screening of genetically modified photosynthetic organisms for plasmic state. The present invention provides methods of producing one or more proteins, including biomass degrading enzymes in a plant. Also provided are the methods of producing biomass degradation pathways in alga cells, particularly in the chloroplast. Single enzymes or multiple enzymes may be produced by the methods disclosed. The methods disclosed herein allow for the production of biofuel, including ethanol.
    Type: Grant
    Filed: October 7, 2011
    Date of Patent: November 27, 2012
    Assignees: Sapphire Energy, Inc., The Scripps Research Institute
    Inventors: Stephen Mayfield, Bryan O'Neill, Michael Mendez, Yan Poon
  • Patent number: 8316933
    Abstract: Efficient, economical and environmentally safe microbial methods to enhance oil recovery in existing oil reservoirs, as well as microorganisms useful in such methods. The microorganisms are capable of growing in an environment of high salinity, and are deficient in their ability to degrade short chain hydrocarbons of about 12 carbons or less.
    Type: Grant
    Filed: August 26, 2010
    Date of Patent: November 27, 2012
    Assignee: Geo Fossil Fuels LLC
    Inventor: William J. Kohr
  • Patent number: 8318484
    Abstract: The invention is directed to isolated renal cells, including tubular and erythropoietin (EPO)-producing kidney cell populations, and methods of isolating and culturing the same, as well as methods of treating a subject in need with the cell populations.
    Type: Grant
    Filed: November 12, 2009
    Date of Patent: November 27, 2012
    Assignee: Tengion, Inc.
    Inventors: Sharon C. Presnell, Andrew Bruce, Shay M. Wallace, Sumana Choudhury, Russell W. Kelley, Manuel J. Jayo, Jessica J. Reinsch, Patricia D. Tatsumi, Timothy A. Bertram, Eric S. Werdin, Oluwatoyin A. Knight, H. Scott Rapoport, Roger M. Ilagan
  • Patent number: 8318163
    Abstract: The invention provides crystal structures of neuropilin 1 (Nrp1) and neuropilin 2 (Nrp2) fragments alone and in complex with anti-neuropilin antibodies, and method for their use. The invention further provides anti-Nrp antibodies and methods for their therapeutic applications.
    Type: Grant
    Filed: May 17, 2007
    Date of Patent: November 27, 2012
    Assignee: Genentech, Inc.
    Inventors: Brent A. Appleton, Christian Wiesmann, Yan Wu
  • Patent number: 8309087
    Abstract: The present invention concerns the treatment of disorders characterized by the overexpression of ErbB2. More specifically, the invention concerns the treatment of human patients susceptible to or diagnosed with cancer overexpressing ErbB2 with a combination of an anti-ErbB2 antibody and a chemotherapeutic agent other than an anthracycline, e.g. doxorubicin or epirubicin. The invention further provides a method of treating cancer in a human patient comprising administering effective amounts of an anti-ErbB2 antibody and a cardioprotectant to the patient.
    Type: Grant
    Filed: May 9, 2011
    Date of Patent: November 13, 2012
    Assignee: Genentech, Inc.
    Inventor: Susan D. Hellmann
  • Patent number: 8304615
    Abstract: The present invention includes broccoli plants with curds having detached florets and methods for obtaining such broccoli plants. The present invention also provides reagents that can be used in methods for obtaining such broccoli plants.
    Type: Grant
    Filed: July 29, 2011
    Date of Patent: November 6, 2012
    Assignee: Seminis Vegetable Seeds, Inc.
    Inventors: Franciscus van den Bosch, Meinardus Petrus Boon
  • Patent number: 8299321
    Abstract: Polynucleotides useful for improvement of plants are provided. In particular, polynucleotide sequences are provided from plant sources. Polypeptides encoded by the polynucleotide sequences are also provided. The disclosed polynucleotides and polypeptides find use in production of transgenic plants to produce plants having improved properties.
    Type: Grant
    Filed: October 31, 2007
    Date of Patent: October 30, 2012
    Assignee: Monsanto Technology LLC
    Inventor: Yongwei Cao
  • Patent number: 8300574
    Abstract: An establishment method of uplink synchronization based on the joint transmission technology utilizes channel symmetry and channel time correlation of the downlink and the uplink in TDD mobile communication system, and then applies the joint transmission technology in the uplink synchronization establishment process in a TDD mobile communication system, and based on the simple processing performed by UE, the base station can accurately detect the timing of uplink signals by performing related calculations. The present invention has fundamentally solved the problem of low probability of success in uplink synchronization establishment.
    Type: Grant
    Filed: July 6, 2005
    Date of Patent: October 30, 2012
    Assignee: ZTE Corporation
    Inventor: Meiling Ding
  • Patent number: 8287869
    Abstract: The invention concerns inhibition of the production of proinflammatory cytokine interleukin-17 (IL-17) by T cells, using an antagonist of interleukin-23 (IL-23). The invention further concerns the use of IL-23 antagonists in the treatment of inflammatory diseases characterized by the presence of elevated levels of IL-17. IL-23 antagonists include, without limitation, antibodies specifically binding to a subunit or IL-17 or an IL-17 receptor. The invention additionally concerns induction of IL-7 production by using an IL-23 agonist.
    Type: Grant
    Filed: January 7, 2009
    Date of Patent: October 16, 2012
    Assignee: Genentech, Inc.
    Inventor: Austin L. Gurney
  • Patent number: 8288617
    Abstract: A squash plant having high level geminivirus resistance and a method for developing a squash plant having high resistance to geminvirus.
    Type: Grant
    Filed: August 25, 2008
    Date of Patent: October 16, 2012
    Assignee: Seminis Vegetable Seeds, Inc.
    Inventors: William C Johnson, John Kao
  • Patent number: 8278042
    Abstract: The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
    Type: Grant
    Filed: March 22, 2010
    Date of Patent: October 2, 2012
    Assignee: Genentech, Inc.
    Inventors: Belinda Cairns, Ruihuan Chen, Gretchen Frantz, Kenneth J. Hillan, Hartmut Koeppen, Heidi S. Phillips, Paul Polakis, Susan D. Spencer, Victoria Smith, P. Mickey Williams, Thomas D. Wu, Zemin Zhang
  • Patent number: 8279808
    Abstract: The methods and devices of the present disclosure may be used to enable non-carrier dependent, Voice over Internet Protocol (VoIP) femtocells for in-service use with one or more mobile handheld devices. The VoIP femtocell generally includes at least one Radio Frequency (RF) transceiver; and program logic that, at least in part, performs a broadcast channel selection protocol and a handheld reselection protocol, so as to enable one or more mobile handheld devices to select the VoIP femtocell for in-service use. In certain embodiments, the broadcast channel selection protocol includes a configuration phase and a broadcast phase.
    Type: Grant
    Filed: May 5, 2010
    Date of Patent: October 2, 2012
    Assignee: YMax Communications Corp.
    Inventors: YuenWah Sing, Daniel M. Borislow, Gregory L. Wood