Patents Represented by Attorney Arnold & Porter LLP

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  • Nucleic acid molecules and other molecules associated with the phosphogluconate pathway
    Patent number: 7655770
    Abstract: The present invention is in the field of plant biochemistry. More specifically the invention relates to nucleic acid sequences from plant cells, in particular, nucleic acid sequences from maize and soybean associated with the phosphogluconate pathway enzymes. The invention encompasses nucleic acid molecules that encode proteins and fragments of proteins. In addition, the invention also encompasses proteins and fragments of proteins so encoded and antibodies capable of binding these proteins or fragments. The invention also relates to methods of using the nucleic acid molecules, proteins and fragments of proteins and antibodies, for example for genome mapping, gene identification and analysis, plant breeding, preparation of constructs for use in plant gene expression and transgenic plants.
    Type: Grant
    Filed: April 28, 1999
    Date of Patent: February 2, 2010
    Assignee: Monsanto Technology LLC
    Inventors: Nordine Cheikh, Jingdong Liu, Virginia M. Peschke
  • Nucleic acid molecules and other molecules associated with the cytokinin pathway
    Patent number: 7655469
    Abstract: The present invention is in the field of plant biochemistry. More specifically the invention relates to nucleic acid sequences from plant cells, in particular, nucleic acid sequences from maize and soybean plants associated with the cytokinin pathway. The invention encompasses nucleic acid molecules that encode proteins and fragments of proteins. In addition, the invention also encompasses proteins and fragments of proteins so encoded and antibodies capable of binding these proteins or fragments. The invention also relates to methods of using the nucleic acid molecules, proteins and fragments of proteins and antibodies, for example for genome mapping, gene identification and analysis, plant breeding, preparation of constructs for use in plant gene expression and transgenic plants.
    Type: Grant
    Filed: October 15, 2001
    Date of Patent: February 2, 2010
    Assignee: Monsanto Technology LLC
    Inventors: Nordine Cheikh, Jingdong Liu
  • Nucleic acid molecules associated with the methionine synthesis and degradation pathways
    Patent number: 7635764
    Abstract: The present invention is in the field of plant biochemistry. More specifically the invention relates to nucleic acid sequences from plant cells, in particular, DNA sequences from maize and soybean plants associated with the methionine pathway. The invention encompasses nucleic acid molecules that encode proteins and fragments of proteins. In addition, the invention also encompasses proteins and fragments of proteins so encoded and antibodies capable of binding these proteins or fragments. The invention also relates to methods of using the nucleic acid molecules, proteins and fragments of proteins and antibodies, for example for genome mapping, gene identification and analysis, plant breeding, preparation of constructs for use in plant gene expression and transgenic plants.
    Type: Grant
    Filed: October 7, 2004
    Date of Patent: December 22, 2009
    Assignee: Monsanto Technology LLC
    Inventors: Stefan A. Bledig, Joseph R. Byrum, Jingdong Liu
  • Nucleotide and amino acid sequences from strain Xs85831 and uses thereof
    Patent number: 7629444
    Abstract: The present invention relates to nucleic acid sequences from Xenorhabdus, and, in particular, to genomic DNA sequences, and to nucleotide sequences that encode insecticidal proteins from Xenorhabdus bovienii, strain Xs85831. The invention encompasses nucleic acid molecules present in non-coding regions as well as nucleic acid molecules that encode proteins, fragments of proteins, tRNA's, fragments of tRNA's, rRNA's, and fragments of rRNA's. In addition, proteins and fragments thereof and antibodies capable of binding specifically to the proteins are encompassed by the present invention. The invention also relates to methods of using the disclosed nucleic acid molecules, proteins, protein fragments, RNA's, and antibodies, for example, for gene identification and analysis, preparation of constructs, and protecting plants from insect infestations.
    Type: Grant
    Filed: June 10, 2005
    Date of Patent: December 8, 2009
    Assignee: Monsanto Technology LLC
    Inventors: Barry S. Goldman, Karina Krasomil-Osterfeld, Wei Wu
  • Nucleic acid molecules encoding a ferrochelatase enzyme or fragment thereof
    Patent number: 7625738
    Abstract: The present invention is in the field of plant biochemistry. More specifically the invention relates to nucleic acid sequences from plant cells, in particular, nucleic acid sequences from maize and soybean associated with the tetrapyrrole pathway. The invention encompasses nucleic acid molecules that encode proteins and fragments of proteins. In addition, the invention also encompasses proteins and fragments of proteins so encoded and antibodies capable of binding these proteins or fragments. The invention also relates to methods of using the nucleic acid molecules, proteins and fragments of proteins and antibodies, for example for genome mapping, gene identification and analysis, plant breeding, preparation of constructs for use in plant gene expression and transgenic plants.
    Type: Grant
    Filed: January 11, 2006
    Date of Patent: December 1, 2009
    Assignee: Monsanto Technology LLC
    Inventors: Claire A. CaJacob, Jingdong Liu
  • Fusion polypeptides, and use thereof in antivascular tumor therapy
    Patent number: 7618943
    Abstract: The present invention relates to fusion polypeptides, comprising at least two peptides. The invention further relates to the use of these fusion proteins in antivascular therapy of neoplastic diseases and to their use I the production of a drug for the treatment of neoplastic diseases.
    Type: Grant
    Filed: August 20, 2004
    Date of Patent: November 17, 2009
    Assignee: Oncoscience AG
    Inventors: Wolfgang E. Berdel, Rolf M. Mesters
  • Methods for coupling resistance alleles in tomato
    Patent number: 7615689
    Abstract: A Lycopersicon esculentum plant comprising within its genome at least one tomato yellow leaf curl virus (TYLCV) resistance allele and at least one root knot nematode resistance allele, characterized in that the resistance alleles are present in coupling phase at different loci on one chromosome and in that the plant is highly resistant both against TYLCV and to at least one root knot nematode species selected from the group consisting of Meloidogyne arenaria, Meloidogyne incognita and Meloidogyne javanica.
    Type: Grant
    Filed: February 11, 2005
    Date of Patent: November 10, 2009
    Assignee: Seminis Vegatable Seeds, Inc.
    Inventors: Jacobus Gerardus Joannes Hoogstraten, Carl J. Braun, III
  • Method for sorting tumor cells
    Patent number: 7604933
    Abstract: The present invention relates to a method for storing cells, wherein the cells are stored in a composition comprising a base nutritive medium and liposomes at temperatures in the range of ?196° C. to 37° C., characterized in that the liposomes comprise one or more sterols and that the cells are tumor cells. More specifically, the invention relates to simple and effective methods for storing tumor cells, wherein the RNA and/or DNA in the cells is essentially not degraded, such that the RNA and/or DNA can be analyzed after storage.
    Type: Grant
    Filed: May 7, 2004
    Date of Patent: October 20, 2009
    Assignee: Oncoscience AG
    Inventors: Ferdinand Bach, Joseph Fischer
  • Nucleic acid constructs and methods for producing altered seed oil compositions
    Patent number: 7601888
    Abstract: The present invention is in the field of plant genetics and provides recombinant nucleic acid molecules, constructs, and other agents associated with the coordinate manipulation of multiple genes in the fatty acid synthesis pathway. In particular, the agents of the present invention are associated with the simultaneous enhanced expression of certain genes in the fatty acid synthesis pathway and suppressed expression of certain other genes in the same pathway. Also provided are plants incorporating such agents, and in particular plants incorporating such constructs where the plants exhibit altered seed oil compositions.
    Type: Grant
    Filed: March 21, 2003
    Date of Patent: October 13, 2009
    Assignee: Monsanto Technology L.L.C.
    Inventors: Joanne J. Fillatti, Neal A. Bringe, Katayoon Dehesh
  • Nucleic acid molecules and other molecules associated with the sucrose pathway
    Patent number: 7598361
    Abstract: The present invention is in the field of plant biochemistry. More specifically the invention relates to nucleic acid sequences from plant cells, in particular, nucleic acid sequences from maize and soybean plants associated with the sucrose pathway. The invention encompasses nucleic acid molecules that encode proteins and fragments of proteins. In addition, the invention also encompasses proteins and fragments of proteins so encoded and antibodies capable of binding these proteins or fragments. The invention also relates to methods of using the nucleic acid molecules, proteins and fragments of proteins and antibodies, for example for genome mapping, gene identification and analysis, plant breeding, preparation of constructs for use in plant gene expression and transgenic plants.
    Type: Grant
    Filed: January 26, 1999
    Date of Patent: October 6, 2009
    Assignee: Monsanto Technology LLC
    Inventors: Nordine Cheikh, Dane K. Fisher, Jingdong Liu
  • Identification of a gene expression profile that differentiates ischemic and nonischemic cardiomyopathy
    Patent number: 7592138
    Abstract: A method of preparing a gene expression prediction profile for distinguishing ischemic and nonischemic cardiomyopathy comprises the steps of obtaining clinical specimens from patients suffering from ischemic or nonischemic cardiomyopathy, isolating nucleic acid sequences from at least a plurality of said specimens, obtaining a gene expression level corresponding to each individual of said nucleic acid sequence by a gene expression profiling method, identifying genes having differences in gene expression by comparing the gene expression level of an ischemic specimen with the gene expression level of a nonischemic specimen, and identifying a gene expression prediction profile comprises genes identified as having differences in gene expression so that said prediction profile distinguishes ischemic and nonischemic cardiomyopathy.
    Type: Grant
    Filed: December 15, 2004
    Date of Patent: September 22, 2009
    Inventors: Joshua M. Hare, Michelle M. Kittleson
  • Lewis acid mediated synthesis of cyclic esters
    Patent number: 7582758
    Abstract: Methods for the synthesis of cyclic phosphonic acid diesters from 1,3-diols are described, whereby cyclic phosphonic acid diesters are produced by reacting a chiral 1,3-diol and an activated phosphonic acid in the presence of a Lewis acid.
    Type: Grant
    Filed: June 3, 2005
    Date of Patent: September 1, 2009
    Assignee: Metabasis Therapeutics, Inc.
    Inventor: Kevin V. Martin
  • Nucleic acid molecules seq id No. 16372 and other molecules associated with plants
    Patent number: 7572902
    Abstract: Expressed Sequence Tags (ESTs) isolated from maize are disclosed. The ESTs provide a unique molecular tool for the targeting and isolation of novel genes for plant protection and improvement. The disclosed ESTs have utility in the development of new strategies for understanding critical plant developmental and metabolic pathways. The disclosed ESTs have particular utility in isolating genes and promoters, identifying and mapping the genes involved in developmental and metabolic pathways, and determining gene function. Sequence homology analyses using the ESTs provided in the present invention, will result in more efficient gene screening for desirable agronomic traits. An expanding database of these select pieces of the plant genomics puzzle will quickly expand the knowledge necessary for subsequent functional validation, a key limitation in current plant biotechnology efforts.
    Type: Grant
    Filed: January 12, 2006
    Date of Patent: August 11, 2009
    Assignee: Monsanto Technology LLC
    Inventors: Mark S. Abad, Scott E. Andersen, Patrice Dubois, Debbie A. Mahadeo, James D. Masucci
  • Nucleic acid constructs and methods for producing altered seed oil compositions
    Patent number: 7566813
    Abstract: The present invention is in the field of plant genetics and provides recombinant nucleic acid molecules, constructs, and other agents associated with the coordinate manipulation of multiple genes in the fatty acid synthesis pathway. In particular, the agents of the present invention are associated with the simultaneous enhanced expression of certain genes in the fatty acid synthesis pathway and suppressed expression of certain other genes in the same pathway. Also provided are plants incorporating such agents, and in particular plants incorporating such constructs where the plants exhibit altered seed oil compositions.
    Type: Grant
    Filed: March 16, 2006
    Date of Patent: July 28, 2009
    Assignee: Monsanto Technology, L.L.C.
    Inventors: Toni Voelker, JoAnne J. Fillatti, Neal A. Bringe, Tim Ulmasov
  • Lettuce varieties having both iceberg and romaine lettuce characteristics and methods of making and using
    Patent number: 7563952
    Abstract: The present invention relates to an iceberg lettuce having one or more romaine lettuce characteristics. The invention further relates to methods for producing iceberg lettuce varieties containing one or more romaine lettuce characteristics.
    Type: Grant
    Filed: September 16, 2003
    Date of Patent: July 21, 2009
    Assignee: Seminis Vegetable Seeds, Inc.
    Inventor: William Waycott
  • Nucleic acid sequences and methods of use for the production of plants with modified polyunsaturated fatty acids
    Patent number: 7563949
    Abstract: The present invention is directed to nucleic acid molecules and nucleic acid constructs, and other agents associated with fatty acid synthesis, particularly the ratios of saturated and unsaturated fats. Moreover, the present invention is directed to plants incorporating such agents where the plants exhibit altered ratios of saturated and unsaturated fats. In particular, the present invention is directed to plants incorporating such agents where the plants exhibit altered ratios of monounsaturated to polyunsaturated fatty acids.
    Type: Grant
    Filed: March 8, 2006
    Date of Patent: July 21, 2009
    Assignee: Monsanto Technology LLC
    Inventor: JoAnne J. Fillatti
  • Nucleic acid molecule SEQ ID NO. 68811 and other molecules associated with plants
    Patent number: 7560542
    Abstract: Expressed Sequence Tags (ESTs) isolated from maize are disclosed. The ESTs provide a unique molecular tool for the targeting and isolation of novel genes for plant protection and improvement. The disclosed ESTs have utility in the development of new strategies for understanding critical plant developmental and metabolic pathways. The disclosed ESTs have particular utility in isolating genes and promoters, identifying and mapping the genes involved in developmental and metabolic pathways, and determining gene function. Sequence homology analyses using the ESTs provided in the present invention, will result in more efficient gene screening for desirable agronomic traits. An expanding database of these select pieces of the plant genomics puzzle will quickly expand the knowledge necessary for subsequent functional validation, a key limitation in current plant biotechnology efforts.
    Type: Grant
    Filed: February 14, 2006
    Date of Patent: July 14, 2009
    Assignee: Monsanto Technology LLC
    Inventors: Scott E. Andersen, Timothy W. Conner, Raghunath V. Lalgudi
  • Nucleic acid molecules and other molecules associated with plants
    Patent number: 7557201
    Abstract: Expressed Sequence Tags (ESTs) isolated from cotton are disclosed. The ESTs provide a unique molecular tool for the targeting and isolation of novel genes for plant protection and improvement. The disclosed ESTs have utility in the development of new strategies for understanding critical plant developmental and metabolic pathways. The disclosed ESTs have particular utility in isolating genes and promoters, identifying and mapping the genes involved in developmental and metabolic pathways, and determining gene function. Sequence homology analyses using the ESTs provided in the present invention, will result in more efficient gene screening for desirable agronomic traits. An expanding database of these select pieces of the plant genomics puzzle will quickly expand the knowledge necessary for subsequent functional validation, a key limitation in current plant biotechnology efforts.
    Type: Grant
    Filed: January 13, 2006
    Date of Patent: July 7, 2009
    Assignee: Monsanto Technology LLC
    Inventors: Karen L. Fincher, Thomas J. La Rosa, Jinhua Xiao
  • Cytarabine monophosphate prodrugs
    Patent number: 7553826
    Abstract: Compounds of Formula I, their preparation and uses are described: wherein: M and V are cis to one another and MH is cytarabine; the 5? oxygen of said cytarabine is attached to the phosphorus; V is 4-pyridyl; and pharmaceutically acceptable prodrugs and salts thereof.
    Type: Grant
    Filed: October 18, 2006
    Date of Patent: June 30, 2009
    Assignee: Metabasis Therapeutics, Inc.
    Inventors: Serge Boyer, Mark D. Erion
  • USB device for facilitating VoIP calls
    Patent number: D603864
    Type: Grant
    Filed: January 22, 2008
    Date of Patent: November 10, 2009
    Assignee: YMAX Communications Corp.
    Inventor: Daniel M. Borislow