Abstract: Novel halogenating agents are derived from triaryl phosphites and chlorine or bromine. They are useful in converting 7-acylamino-3-hydroxy-3-cephem compounds to 7-acylamino-3-halo-3-cephems and the corresponding C-7 imino halide cephem derivatives.
Type:
Grant
Filed:
February 1, 1979
Date of Patent:
October 28, 1980
Assignee:
Eli Lilly and Company
Inventors:
Lowell D. Hatfield, Larry C. Blaszczak, Jack W. Fisher