Patents Represented by Attorney Ashe, P.C.

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  • VEGF-related protein
    Patent number: 7629145
    Abstract: A human VEGF-related protein (VRP) has been identified and isolated that binds to, and stimulates the phosphorylation of, the receptor tyrosine kinase Flt4. The VRP is postulated to be a third member of the VEGF protein family. Also provided are antibodies that bind to VRP and neutralize a biological activity of VRP, compositions containing the VRP or antibody, methods of use, chimeric polypeptides, and a signal polypeptide for VRP.
    Type: Grant
    Filed: June 29, 2006
    Date of Patent: December 8, 2009
    Assignee: Genentech, Inc.
    Inventors: James Lee, William Wood