Patents Represented by Attorney B. C. Zielinski

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  • Calcium channel blocking polypeptides from Heteropoda venatoria
    Patent number: 5627154
    Abstract: Polypeptides isolated from the venom of the Heteropoda venanoria spider block calcium channels in cells of various organisms and are useful in blocking said calcium channels in cells, per se, in the treatment of calcium channel-mediated diseases and conditions and in the control of invertebrate pests.
    Type: Grant
    Filed: April 27, 1995
    Date of Patent: May 6, 1997
    Assignee: Pfizer Inc.
    Inventors: Paul R. Kelbaugh, Nicholas A. Saccomano, Robert A. Volkmann
  • Tetrahydro-1H-benzazepinones and hexahydroazepinones as selective cholecystokinin-B receptor antagonists
    Patent number: 5618811
    Abstract: This invention relates to compounds of formula (I) wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4 and X are as defined in the application. These compounds are CCK-B receptor antagonists and are useful in the treatment and prevention of central nervous system and gastrointestinal disorders.
    Type: Grant
    Filed: January 18, 1996
    Date of Patent: April 8, 1997
    Assignee: Pfizer Inc.
    Inventor: John A. Lowe, III
  • Calcium channel blocking polypeptide from agelenopsis aperta and therapeutic methods employing it
    Patent number: 5599559
    Abstract: A polypeptide isolated from the venom of the Agelenopsis aperta spider blocks calcium channels in cells of various organisms and is useful in blocking such calcium channels in cells per se, in the treatment of calcium channel-mediated diseases and conditions, and in the control of invertebrate pests.
    Type: Grant
    Filed: April 27, 1995
    Date of Patent: February 4, 1997
    Assignee: Pfizer Inc.
    Inventors: Douglas Phillips, Mary E. Kelly, Nicholas A. Saccomano, Robert A. Volkmann