Abstract: A gun suitable for firing paintballs or pellets using compressed gas having an elongate breech section with a longitudinal passageway formed therein and a handle and barrel connected thereto. A hammer is slidably mounted in the passageway and a spring biases the hammer to a forward, firing position. A gas valve system is arranged in the passageway and is connectible to a source of compressed gas. A trigger includes a sear engaging member slidable in a cavity formed in the trigger. A spring biases this member to a rearward position. A sear with a downwardly extending hook is pivotally mounted on a sear pin. A further spring biases the sear so as to pivot the rear end upwardly into engagement with a flange formed on the bolt of the gun. Preferably the hammer and bolt are rigidly connected together by means of two links positioned on opposite sides of the hammer and bolt to which they are both connected.
Abstract: A semiconductor integrated circuit device capable of changing the product specification. The semiconductor integrated circuit device comprises an integrated circuit section containing a first circuit section having a first function and a second circuit section having a second function, and active signal generator means for producing an active signal for activating the first circuit section or the second circuit section. To change the product specification, the integrated circuit device further comprises receiving means for taking in a decision signal for determining the product specification, switching signal generator means, connected to the receiving means, for producing a switching signal for changing the product specification based on the decision signal, and switching means which receives the active signal and the switching signal, and which, based on the switching signal, changes the supply of the active signal to either the first circuit section or to the second circuit section.
Abstract: A modular block wall includes dry cast, unreinforced modular wall blocks with anchor type, or frictional type or composite type soil stabilizing elements recessed therein and attached thereto by vertical rods which also connect the blocks together. The soil stabilizing elements are positioned in counterbores or slots in the blocks and project into the compacted soil behind the courses of modular wall blocks.
Type:
Grant
Filed:
February 14, 1994
Date of Patent:
April 29, 1997
Assignee:
Societe Civile Des Brevets Henri C. Vidal
Inventors:
Peter L. Anderson, Michael J. Cowell, Dan J. Hotek
Abstract: Method for inhibiting aldehyde dehydrogenase activity using daidzin and/or daidzin analog and/or daidzin or daidzin analog in combination with a factor or factors which increase the bioavailability of the daidzin or daidzin analog, as ALDH-I inhibitory compounds or compositions. Such inhibitory compounds or compositions are useful as pharmaceutical compositions in methods for the treatment of alcohol dependence (i.e., alcoholism) or alcohol abuse, for alcohol sensitization, for extinguishing an alcohol-drinking response, for suppressing an urge for alcohol, for inducing alcohol intolerance, for preventing alcoholism in an individual with or without a susceptibility or predisposition to alcoholism or alcohol abuse, and for limiting alcohol consumption in an individual whether or not genetically predisposed.
Type:
Grant
Filed:
May 24, 1994
Date of Patent:
April 29, 1997
Assignee:
The Endowment for Research in Human Biology, Inc.
Abstract: A thin-walled, condom-like tubular protective device for protection against the transfer of infectious matter during sexual intercourse is disclosed. The condom-like device has an open end a collar-shaped outwardly extending portion with an apparatus for radially stretching the collar and has an inner diameter which is sufficiently large to permit movement of a penis with respect to the protective device during coitus.
Abstract: Episomal plasmids containing a papovavirus origin of replication and a papovavirus large T antigen mutant form are shown to replicate episomally in human cells, and yield levels of gene expression proportional to their episomal copy number. In conjunction with liposomal or receptor-mediated delivery systems, papovavirus-derived episomal plasmids provide an alternative vector for gene therapy, particularly when utilizing strategies requiring high levels of gene expression.
Abstract: The device, for use in contraception and in preventing transmission of sexually transmitted diseases, comprises a thin, flexible pouch having an open end in the form of a peripheral flange with a peripheral ribbed rim, and a closed end. An insert is provided within the closed end of the pouch so as to protect the pouch during insertion thereof into the vagina by means of an applicator rod or the like. The insert, which is typically absorbent and of flexible expanded plastics material, and may have dispersed therein a spermicide and/or an antiviral agent, comprises a central portion and four spurs. A continuous coating layer of an adhesive material which can temporarily adhere the barrier device to mucous membrane material in the presence of aqueous body fluids is preferably provided on the vulva-contacting surface of the flange and/or on the vagina-contacting surface of the pouch.
Type:
Grant
Filed:
January 23, 1995
Date of Patent:
April 22, 1997
Assignee:
Chartex International plc
Inventors:
Margaret P. Richardson, Philip Richardson
Abstract: This invention encompasses a method and compositions which inhibit pancreatic cholesterol esterase and triglyceride lipase and hence, lower cholesterol and triglycerides in the blood stream.
Type:
Grant
Filed:
August 1, 1994
Date of Patent:
April 1, 1997
Inventors:
Louis G. Lange, III, Curtis A. Spilburg
Abstract: A wireless interactive consumer video system and a method for wireless communication between an input and display unit and a video electronics unit. The input and display unit includes a key pad and a video display. The input device accepts a user entry and generates a data signal corresponding to the user entry. The input and display unit transmits the data signal to the video electronics unit, which generates a video signal responsive to the data signal. The video signal is then provided to the input and display unit, which provides an image on the video display.
Type:
Grant
Filed:
October 31, 1994
Date of Patent:
March 4, 1997
Assignee:
RTC Industries, Inc.
Inventors:
John W. Swafford, Jr., William P. Carlson
Abstract: A radio communication apparatus intermittently powered in synchronism with an intermittent reception control signal transmitted from a base station is disclosed. The apparatus includes a synthesizer, wherein power supplied to the synthesizer is initiated prior to the power supply to circuits other than the synthesizer.
Abstract: A human gene has been discovered which is genetically altered in human tumor cells. The genetic alteration is gene amplification and leads to a corresponding increase in gene products. Detecting that the gene, designated hMDM2, has become amplified or detecting increased expression of gene products is diagnostic of tumorigenesis. Human MDM2 protein binds to human p53 and allows the cell to escape from p53-regulated growth.
Type:
Grant
Filed:
February 17, 1995
Date of Patent:
February 25, 1997
Assignee:
The Johns Hopkins University
Inventors:
Marilee Burrell, David E. Hill, Kenneth W. Kinzler, Bert Vogelstein
Abstract: A computer comprises a keyboard, and a base with a housing accommodating either a floppy disk drive or part of an external power supply which can be connected to the mains. When the power supply is fitted in the housing, a sensor prepares a reduced output power state. The keyboard is mobile, and there is a hard disk drive which can be removed by raising the keyboard from its operating position.
Abstract: This invention relates to methods and reagents for inhibiting furin endoprotease activity and specifically for inhibiting furin endoprotease-mediated maturation of bioactive proteins in vivo and in vitro. The invention specifically provides proteins capable of inhibiting furin endoprotease activity. Particularly provided are .alpha..sub.1 -antitrypsin variants that specifically inhibit furin endoprotease activity. Methods for using furin endoprotease inhibition to attenuate or prevent viral protein maturation, and thereby alleviate viral infections, are provided. Also provided are methods for using furin endoprotease inhibition to attenuate or prevent proteolytic processing of bacterial toxins, thereby alleviating bacterial infections. Methods are also provided to inhibit proteolytic processing of biologically active proteins and peptides. The invention also provides pharmaceutically acceptable compositions of therapeutically effective amounts of furin endoprotease inhibitors.
Type:
Grant
Filed:
January 8, 1993
Date of Patent:
February 18, 1997
Assignee:
State of Oregon, Acting by and through the Oregon State Board of Higher Education on Behalf of the Oregon Health Sciences University, a non-profit organization
Inventors:
Gary Thomas, Eric D. Anderson, Laurel Thomas, Joel S. Hayflick
Abstract: Spinning head for spinning polymer melts, having a filter cartridge made of a seamless metal cloth cylinder having an end cap and a connector, said cartridge being disposed within a melt passage having a conical taper toward the bottom. The connector is inserted into the melt channel and has a matching conical shape to seal against the channel wall. A die plate having a maximum area of 90 cm.sup.2 connects to the connector. An opening through the connector permits filtered polymer melt to flow from the filter cartridge through the connector to the die plate. A single filter cartridge is provided for each die plate, whereby the ratio of filter area to die plate area is at least 0.5:1.
Abstract: A media library system capable of reducing a time and an average moving distance of the media carrying unit required for exchanging the recording media. The system includes a storehouse having a plurality of storage cells for storing a plurality of recording media, a media driving unit for executing data read/write operation with respect to the recording media, and a media carrying unit for carrying the recording media between the storehouse and the media driving unit, so as to exchange a previously used recording medium mounted on the media driving unit with a new recording medium stored in the storehouse.
Type:
Grant
Filed:
December 2, 1994
Date of Patent:
January 28, 1997
Assignee:
Nippon Telegraph and Telephone Corporation