Abstract: The invention provides an isolated nucleic acid (SEQ ID NO:1) encoding a novel protein, JMY, which is found to be a co-activator of p300/CBP. The invention also provides JMY polypeptides and antibodies thereto, as well as assays for modulators of the cell cycle which target the interaction of JMY with transcription factors such as E2F, ER or TBP.
Type:
Grant
Filed:
May 13, 1999
Date of Patent:
April 23, 2002
Assignee:
The University Court of the University of Glasgow
Inventors:
Nicholas Barrie La Thangue, Noriko Shikama