Abstract: Message send and receive blocks are provided to emulation ICs and reconfigurable interconnect ICs of an emulation system to reduce the multiplexed transfer latency of critical emulation signals. Each of a corresponding pair of a message send block and a message receive block is provided with a signal state value inclusion schedule to control operation of the message send and receive blocks. The signal state inclusion schedule calls for some signals within a message to be sent more often than other signals within the message. In some embodiments a parity value is implemented as part the message and included in the signal state inclusion schedule.

Abstract: Stuttering-treatment techniques using neural stimulation and/or drug delivery. One or more electrodes and/or a catheter are implanted adjacent to sites in the brain. A signal generator and the electrode deliver stimulation to a first site. A pump and the catheter deliver one or more therapeutic drugs to a second site. The first and second sites could be: the supplementary motor area, the centromedian circuit, the dorsomedial nuclei, the lateral prefrontal circuit, or other paramedian thalamic and midbrain nuclei. The stuttering treatment could be performed via periodic transcranial magnetic stimulation. A sensor, located near the patient's vocal folds, can be used for generating a signal responsive to activity of the patient's speech-producing muscles. A controller adjusts one or more stimulation parameters in response to the signal from the sensor.

Abstract: A synthesis is described for intermediates which are readily amenable to the large scale preparation of hydroxyethylurea-based chiral HIV protease inhibitors. The method includes forming a diastereoselective epoxide or cyanohydrin from a chiral alpha amino aldehyde.