Patents Represented by Attorney, Agent or Law Firm Barbara F. Kurys - Justia Patents Search

Patents Represented by Attorney, Agent or Law Firm Barbara F. Kurys

2,19-methyleneoxy and 2,19-methylenethio bridged steroids as aromatase, 19-hydroxylase inhibitors and methods of their use in the treatment of estrogen mediated disorders

Patent number: 6313161

Abstract: The present invention is directed to a method of using a certain compounds which are 2,19-methyleneoxy or 2,19 methylenethio bridged steroids, and related steroidal compounds as inhibitors of the enzyme steroid aromatase, 19-hydroxylase and as treatment for various estrogen dependent/mediated disorders including hormonal dependent breast cancer.

Type: Grant

Filed: October 26, 1999

Date of Patent: November 6, 2001

Assignee: Merrell Pharmaceuticals Inc.

Inventors: Norton P. Peet, J. O'Neal Johnston, Joseph P. Burkhart