Patents Represented by Attorney Barbara Kurys

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  • Compounds useful for DPP-IV enzyme inhibition
    Patent number: 7652021
    Abstract: The present invention relates to the novel compounds of the general formula (I) possessing dipeptidyl peptidase IV enzyme inhibitory activity, pharmaceutical compositions thereof, methods of using said compounds, processes for their preparation and intermediates of the general formulae (II), (IV), (V), (VII), (VIII) and (IX).
    Type: Grant
    Filed: February 28, 2006
    Date of Patent: January 26, 2010
    Assignee: Sanofi-Aventis
    Inventors: Peter Aranyi, Imre Bata, Sandor Batori, Eva Boronkay, Philippe Bovy, Zoltan Kapui, Edit Susan, Tibor Szabo, Katalin Urban-Szabo, Marton Varga
  • Method of treating demyelinating diseases or conditions
    Patent number: 7534803
    Abstract: N-(Pyridinyl)-1H-indol-1-amines of formula I provide a unique combination of blocking properties for both the potassium and sodium channels. These compounds are useful for the treatment of Demyelinating Diseases and Conditions such as Multiple Sclerosis, Spinal Cord Injury, Traumatic Brain Injury and Stroke. The compounds are also useful for Stroke Rehabilitation, the treatment of Bladder Irritation and Dysfunction, and the treatment of Neuropathic Pain and Chemokine-Induced Pain.
    Type: Grant
    Filed: September 27, 2005
    Date of Patent: May 19, 2009
    Assignee: Aventis Pharmaceuticals Inc.
    Inventors: Craig P. Smith, Michel P. Rathbone, Margaret Petty, David Rampe
  • 7-Phenylamino-4-quinolone-3-carboxylic acid derivatives, process for their preparation and their use as medicaments
    Patent number: 7402674
    Abstract: 7-Phenylamino-4-quinolone-3-carboxylic acid derivatives, process for their preparation and their use as medicaments The invention relates to 7-phenylamino-4-quinolone-3-carboxylic acid derivatives and to the physiologically tolerated salts and physiologically functional derivatives thereof. The invention relates to compounds of the formula I in which the radicals have the stated meanings, and to the physiologically tolerated salts thereof. The compounds are suitable for example as medicaments for the prevention and treatment of type 2 diabetes.
    Type: Grant
    Filed: January 25, 2005
    Date of Patent: July 22, 2008
    Assignee: Sanofi-Aventis Deutschland GmbH,
    Inventors: Elisabeth Defossa, Dieter Kadereit, Sven Ruf, Thomas Klabunde, Dieter Schmoll, Andreas Herling, Karl-Ulrich Wendt
  • Acyl-4-carboxyphenylurea derivatives, processes for preparing them and their use
    Patent number: 7223796
    Abstract: The invention relates to acyl-4-carboxyphenylurea derivatives and to their physiologically tolerated salts and physiologically functional derivatives. The invention particularly relates to compounds of formula I, in which the radicals have the given meanings described herein, and to their physiologically tolerated salts and processes for preparing them. The compounds are, for example, suitable for use as antidiabetics.
    Type: Grant
    Filed: April 10, 2003
    Date of Patent: May 29, 2007
    Assignee: Sanofi-aventis Deutschland GmbH
    Inventors: Elisabeth Defossa, Dieter Kadereit, Karl Schoenafinger, Thomas Klabunde, Hans-Joerg Burger, Andreas Herling, Karl-Ulrich Wendt, Erich Von Roedern, Alfons Enhsen, Joerg Rieke-Zapp
  • Mercaptoacetylamino 1,3,4,5-tetrahydro-benzo(C)azepin-2-one disulfide derivatives useful as inhibitors of enkephalinase and ACE
    Patent number: 5880119
    Abstract: The present invention relates to certain novel mercaptoacetylamido 1,3,4,5-tetrahydro-benzo?c!azepin-3-one disulfide derivatives useful as inhibitors of enkephalinase and of ACE.
    Type: Grant
    Filed: August 12, 1997
    Date of Patent: March 9, 1999
    Assignee: Merrell Pharmaceuticals Inc.
    Inventors: Gary A. Flynn, Douglas W. Beight, Alan M. Warshawsky, Shujaath Mehdi, John F. French, John H. Kehne