Abstract: The cellular effects of potentially therapeutic compounds are characterized in mammalian cells and yeast. In the latter case the effects can be characterized on a genome-wide scale by monitoring changes in messenger RNA levels in treated cells with high-density oligonucleotide probe arrays.
Type:
Grant
Filed:
July 6, 2001
Date of Patent:
February 25, 2003
Assignee:
Affymetrix, Inc.
Inventors:
David J. Lockhart, Lisa Wodicka, Ming Hsiu Ho