Patents Represented by Attorney, Agent or Law Firm Barry J. Swanson
  • Patent number: 6187572
    Abstract: A method is provided for inactivating viral and/or bacterial contamination in blood cellular matter, such as erythrocytes and platelets, or protein fractions. The cells or protein fractions are mixed with chemical sensitizers, frozen or freeze-dried, and irradiated with, for example, UV, visible, gamma or X-ray radiation while in the solid state.
    Type: Grant
    Filed: April 14, 1993
    Date of Patent: February 13, 2001
    Assignee: Baxter International Inc.
    Inventors: Matthew S. Platz, Raymond P. Goodrich, Jr., Nagender Yerram
  • Patent number: 5955256
    Abstract: Viral, bacterial and parasitic contaminants in blood and cell culture containing compositions are inactivated by adding a photosensitizer and a blocking agent to the composition and irradiating the resulting mixture with electromagnetic radiation. Blocking agents reduce photolysis of the photosensitizer by mechanisms not involving the quenching of reactive oxygen species. The blocking agents reduce photolysis which occurs by ring opening. Preferred photosensitizers are quinoline or quinolone.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: September 21, 1999
    Assignee: Baxter International Inc.
    Inventors: Samuel O. Sowemimo-Coker, Nagender Yerram, Raymond P. Goodrich, Jr., Matthew S. Platz
  • Patent number: 5869701
    Abstract: Viral and bacterial contaminants present in biological solutions are inactivated by mixing one of a novel class of photosensitizer with said solution and irradiating the mixture.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: February 9, 1999
    Assignee: Baxter International Inc.
    Inventors: Sang Chul Park, Raymond P. Goodrich, Jr., Nagender Yerram, Samuel O. Sowemimo-Coker, Matthew S. Platz, Brian M. Aquila
  • Patent number: 5789601
    Abstract: Viral and bacterial contaminants present in biological solutions are inactivated by mixing one of a novel class of photosensitizer with said solution and irradiating the mixture.
    Type: Grant
    Filed: April 21, 1995
    Date of Patent: August 4, 1998
    Assignee: Baxter International Inc.
    Inventors: Sang Chul Park, Raymond P. Goodrich, Jr., Nagender Yerram, Samuel O. Sowemimo-Coker, Matthew S. Platz, Brian M. Aquila