Abstract: The invention encompasses the novel compounds of Formula I, which are useful in the treatment of cyclooxygenase-2 mediated diseases.
The invention also encompasses certain pharmaceutical compositions comprising compounds of Formula I as well as methods of treating cyclooxygenase-2 mediated diseases comprising administering to a patient in need of such treatment a non-toxic therapeutically effective amount of a compound of Formula I.
Type:
Grant
Filed:
June 27, 2001
Date of Patent:
October 15, 2002
Assignee:
Merck Frosst Canada & Co.
Inventors:
Chun-Sing Li, Cheuk Kun Lau, Michel Therien, Petpiboon Prasit