Abstract: A computational model for simulating and predicting the electrical and chemical dynamics of the heart. The model consists of a computerized representation of heart anatomy and a system of mathematical equations that describe the spatio-temporal behavior of biophysical quantities such as voltage at various locations throughout the heart. The computer process can present the temporal evolution of the biophysical quantities throughout the computerized anatomical model.
Type:
Grant
Filed:
August 23, 1996
Date of Patent:
September 7, 1999
Assignee:
Physiome Sciences
Inventors:
Raimond Winslow, Donna Rounds, David Scollan
Abstract: A transvalvular impedance measurement made between an atrium and a ventricle electrode of a standard implanted electro-catheter may be used to provide information indicative of the mechanical state of the heart. This information may be used, for example, to control the pacing rate of a rate responsive pacemaker, stimulation intensity self adjust or pacing mode switching. Other uses are also possible in defibrillators.