Abstract: Disclosed are labeling reagents containing fluorescent compounds represented by the general formula ##STR1## where R is a group capable of combining with proteins, Ar is a conjugated double bond system, and n is a whole number. These labeling reagents have high fluorescence emission intensities, give high synthesis yields, permit both solid-phase measurements and liquid-phase measurements in immunoassays, and require less measuring steps.

Abstract: The invention provides spirally wound easy-open containers which comprise a spirally wound body wall having overlapped edges and which have capabilities and benefits associated with conventional butt jointed containers. The overlapped edges of the body wall define an easy-open seam extending helically between the ends of the container. A temporary adhesive between the overlapped edges of the body wall releasably adheres the overlapped edges of the body wall together and allows for opening of the container along the helical, easy-open seam. The easy-open containers provided according to the invention can be readily manufactured with only slight modifications to the conventional manufacturing process. Nevertheless, the easy-open containers of the invention can provide for material savings in container label construction and can allow for vacuum packaging of food products such as dough.

Abstract: The invention provides monoclonal antibodies (Mabs) which are cross-protective against endotoxemia caused by at least two different Gram-negative bacterial strains having different core structures; and methods of production of these antibodies. By use of the Kohler/Milstein procedure involving immunization of mice with a number of different rough strains of heat-killed Gram-negative bacteria, followed by fusion and proper screening of the resulting hybridomas, such murine MAbs are obtained. The murine MAbs may be chimerized or humanized by known methods.

Abstract: There is provided a sensitive multiplex RT-PCR assay for the detection of circulating prostate antigen expressing cells. Multiplex PCR uses multiple sets of primers to concurrently amplify different DNA sequences that can be readily resolved by gel electrophoresis. When applied to blood samples from prostate cancer patients, the nested multiplex RT-PCR can simultaneously detect PSA-expressing cells, PSM-expressing cells, and a ubiquitously expressed internal PCR control gene, glyceraldehyde 3-phosphate dehydrogenase (G3PDH), all within a single reaction.

Abstract: An aluminum-alloy article such as a fastener is prepared by providing an aluminum-alloy article precursor that is not in its final heat-treated state, and in one form is in its solution treated/annealed state. A curable organic coating material is also provided. The method includes anodizing the article precursor, preferably in chromic acid solution and without chemical sealing during anodizing, applying the organic coating material to the aluminum-alloy article precursor, and precipitation heat-treating the coated aluminum article precursor to its final heat-treated state, thereby simultaneously curing the organic coating. If the aluminum alloy temper is of the naturally aging type, it is optionally lightly deformed prior to precipitation treatment aging.

Abstract: A method and a device for particularly rapidly producing wells (18) in the surface of a rotating rotogravure cylinder (2) by a pulsed laser beam (13), which is deflected and directed via an optical lens (7) onto the surface of the rotogravure cylinder (2) to be processed. The power of a single laser beam pulse is adjusted in such a way that it is sufficient for removing the maximum volume needed for a well (18). Furthermore, the laser beam (13) is deflected by an optoacoustic modulator (8) by diffraction onto the optical axis of the lens (7), and the individual laser beam pulses are controlled in their pulse power by the same modulator (8) in accordance with the volumes of the wells to be formed.

Abstract: A process is described in which PCR-based cDNA libraries with anchored ends are made, a PCR-based cDNA subtracted (PCSUB) library is produced therefrom, and the ends of a cDNA clone are isolated, via PCR, from an anchored-ends library.

Abstract: The present invention is directed to the treatment of vascular disorders particularly arteriosclerosis and atherosclerosis in warm-blooded animals. The invention encompasses the ingestion, by warm-blooded animals, of eggs or egg fractions derived from female avians that have been hyperimmunized with specific bacterial antigens or groups of bacterial antigens. The invention is directed to methods of controlling cholesterol levels, lipid deposits, and the development of atheromatous lesions in warm-blooded animals by the ingestion of eggs or fractions thereof produced in female avians hyperimmunized with specific bacterial antigens. The invention is also directed to methods of producing the eggs and to vaccines for hyperimmunization of the female avians.

Abstract: An arrangement for feeding stock to a headbox in a papermaking machine which comprises at least one stock header with an inlet for receiving stock into the header and a plurality of stock header outlets permitting stock to leave the header. For each stock header outlet there is a stock conduit downstream of the stock header outlet permitting stock to pass from the stock header outlet, through the conduit to the inlet of the headbox. The arrangement includes a dilution header for feeding a diluent such as water to a plurality of stock conduits. The dilution header has an inlet for receiving a diluent into the dilution header and a plurality of outlets permitting the diluent to leave the dilution header. For each dilution header outlet, there is a diluent conduit permitting the passage of a diluent from the dilution header into a stock conduit.

Abstract: A resilient edge adapter is provided for defining an edge of a drainable athletic playing surface formed of a moldable material. The edge adapter includes a base portion for cooperably engaging an upper portion of a drainage channel and an upstanding portion extending upwardly from the base portion for restraining the moldable material when applied adjacent to the drainage channel, thereby defining an edge of the athletic playing surface. The upstanding portion may be formed of a resilient and elastically deformable material and the base portion may include an elongate continuous plug portion to cooperably engage a corresponding slot defined in the upper edge of the channel. An edge adapter is also provided which has a pair of upstanding portions extending upwardly from a base portion for forming a running track surface over both opposed edges of a grate. Associated methods for forming athletic playing surfaces are also provided.

Abstract: A water craft assembly comprising a towboat (1) and a barge (2) pushed and steered by the towboat (1) and which is designed and constructed for use in shallow water with an optimal cargo-carrying capacity, and wherein the towboat includes a paddle wheel drive mounted in its stern.

Abstract: The present invention relates to extensible endless conveyor belt support structures and systems. A support structure has vertical support members (8) connected by V-shaped arrangements of pivotally connected (17, 19) link members (7, 9). By mounting at least the upper belt run rollers (4) on the vertical supports (8) the load can be more effectively supported whilst providing a relatively high ratio of extended to contracted length. By using telescopically extendable (14, 15) vertical supports (8), any increase in overall height of the support structure upon contraction thereof is minimized or avoided. By also having detachable lower belt run rollers (23) the support structure can be inserted into an endless conveyor belt installation without dismantling or even stopping running thereof. The invention also provides systems including setting devices for holding the support structures in their contracted form and deploying and collecting them into and from their extended conditions.

Abstract: The invention is directed to a variety of articles which include a sheet of microcellular foam material. Exemplary articles include release liner sheets, face stock, label stock, and the like. The cell density of the sheet of microcellular foam material lies in a range from about 10.sup.9 to about 10.sup.15 cells per cubic centimeter of the sheet, and the average size of the cells is less than about 10 microns. The invention also provides processes for the manufacture of articles which include a sheet of microcellular foam material as a component thereof.

Abstract: A method to increase the damage resistance of a diffusion bonded panel that includes embedding reinforcing members in the panel are bonding the reinforcing members so structural redundancy occurs adjacent the bonds and the structures constructed thereby. The reinforcing members stop cracking of the panel there across by taking on the load at the end of the crack so crack growth is retarded.

Abstract: A composite structure having an externally accessible electrical device embedded therein includes at least one tube disposed within the composite structure and extending from a first end which is electrically connected to an electrical lead of the electrical device to a second end which opens through the edge surface of the composite structure to thereby define an externally accessible electrical port. By plugging a corresponding connector into the electrical port, electrical contact can be established via the electrical lead with the electrical device embedded within the composite structure. By extending through the edge surface of the composite structure, the electrical ports can be accessed during the fabrication of the composite structure such that the operations of the embedded electrical device can be monitored.

Abstract: This invention relates to a ramp design permitting the positioning of a cargo ramp floor at any angle or height, which is integral with the aircraft such that it can be aligned to a vehicle transferring the load. The adjustable cargo platform assembly and the automated platform leveling system permits the ramp and ramp platform to be raised or lowered, but also permits the ramp platform to be tilted about a roll axis and aligned laterally with the floor of the load carrying vehicle to allow the cargo to be transferred to the aircraft. Efficient on-loading and off-loading of a palletized loading system (PLS) flatrack, directly off a PLS truck is achieved by such alignment. Actuators in the forward end of the ramp lift the platform as it rotates about the aft hinge point until the platform is even with the bottom of flatrack.

Abstract: A plurality of polypeptides derived from intercellular spaces of plant cells having frost tolerance. Some of the polypeptides are ice nucleators for developing ice crystals in extracellular spaces of plant tissue, some of the polypeptides are antifreeze components which control ice crystal growth in extracellular spaces and some of the polypeptides are enzymes which adapt plant cell walls to function differently during formation of ice crystals in plant intercellular spaces.

Abstract: Polyalkenylaromatic-polyethylene copolymers are prepared using protected functional organolithium initiators. Polymerization of an alkenylsubstituted aromatic monomer followed by ethylene, results in a protected functional block polystyrene-co-polyethylenyllithium. Termination with a functionalizing agent followed by deprotection produces polymeric products with high functionalization at the initiating chain-end and at least partial functionalization at the terminal chain-end.