Abstract: Methods are disclosed for removing retained mucus secretions from the lungs of a human subject. The method includes (1) generating an aerosol suspension of respirable solid, dry particulate amiloride, and (2) delivering by inhalation the aerosol suspension to the respiratory system of the subject. The solid particulate amiloride is comprised of particles of about 1 to 5 microns and is free of liquid amiloride particles. The aerosol suspension of respirable solid particulate amiloride is administered in an amount sufficient to achieve concentrations of amiloride on the airway surfaces of from about 10.sup.-7 to 10.sup.-3 Moles/liter. As a result of the treatment, the secretions are hydrated and more easily transported from the lung via mucociliary action. Methods are also disclosed for the treatment of cystic fibrosis in humans.

Abstract: A method of treating a subject under cardiac arrest comprises the steps of: blocking the descending aorta of the subject; then withdrawing blood from the subject; oxygenating the blood withdrawn from the subject; and perfusing the aortic arch of the subject with oxygenated blood in an amount effective to deliver oxygen to the heart of the subject. This method enables the subject to continue to receive oxygenating material (i.e., blood in this instance) without the danger of volume overload that would be present if another oxygenated solution were continuously infused.

Abstract: A method for providing luminescence to fibrous material is provided. The method includes combining a metal aluminate oxide pigment with a thermoplastic polymer, and then heating, mixing, and extruding the combination into a fiber. A luminescent fiber comprising a thermoplastic polymer and metal aluminate oxide pigment, and articles of manufacture comprising such fibers are also provided.

Abstract: The present invention provides methods for treating Cryptococcus neoformans, Cryptosporidium parvum, and Candida albicans in a subject in need of such treatment. The methods comprises administering to the subject a compound of Formula I: ##STR1## wherein: X is located in the para or meta positions and is loweralkyl, loweralkoxy, alkoxyalkyl, hydroxyalkyl, aminoalkyl, alkylaminoalkyl, cycloalkyl, aryl, alkylaryl, halogen, or ##STR2## wherein: each R.sub.2 is independently selected from the group consisting of H, loweralkyl, alkoxyalkyl, hydroxyalkyl, aminoalkyl, alkylaminoalkyl, cycloalkyl, aryl, or alkylaryl or two R.sub.2 groups together represent C.sub.2 -C.sub.10 alkylene, or two R.sub.2 groups together represent ##STR3## wherein m is from 1-3 and R.sub.4 is H, ##STR4## or --CONHR.sub.5 NR.sub.6 R.sub.7, whereinR.sub.5 is loweralkyl, R.sub.6 and R.sub.7 are each independently selected from the group consisting of H and lower alkyl; each R.sub.

Abstract: A computer based pharmaceutical care cognitive services management system and method allows the transformation of a pharmacist from a vendor to a health care provider. The pharmaceutical care cognitive services management system and method captures all of the value added by a pharmacist to a patient encounter by permitting multiple RARs (Reasons, Actions, Results) to be associated with a single SOAP (Subjective, Objective, Assessment, Plan). This system enables the pharmacist to financially recover for each analytical or counseling session and/or service provided to the user associated with a single transaction. The pharmaceutical care cognitive services management system and method also enables the efficient processing of interruptions to cognitive and counseling sessions.

Abstract: A programmable multi-channel load profile recorder includes a plurality of memory-based tables, such as a load profile configuration table, a plurality of channel and display configuration tables and an operations table, which can be updated when the recorder is reprogrammed in the field to record additional channels of metering quantities or reconfigured with new formulas. The load profile configuration table containing entries therein for each of a plurality of user-selected metering quantities to be recorded. The plurality of channel and display configuration tables contain parameter data and the operations table contains pointers therein to respective memory-based operation modules, each of which contains executable instructions therein. The metering quantities can be quantities such as watt-hours (Wh), var-hours (Vh), volt-ampere-hours (VAh), volt.sup.2 -hours (V.sup.2 h), ampere.sup.2 -hours (A.sup.2 h) and power factor (PF) as well as other user-selected quantities.

Abstract: A method of treating asthma in a subject in need of such treatment comprises contacting Interleukin-8 or an active fragment thereof to the respiratory epithelium of the subject. The active agent is preferably human endothelial IL-8, and is preferably contacted to the subject's respiratory epithelium by causing the subject to inhale respirable particles comprised of the active agent.

Abstract: Processes for making compounds of Formulae XIV, XV, and XVII ##STR1## wherein R.sub.6 is lower alkyl, R.sub.7 is lower alkyl, R is lower alkyl, Y is H, F or Cl, R.sub.8 is a compound of Formula XVIII ##STR2## wherein n is 1, 2, or 3, R.sub.11 is C.sub.1 -C.sub.4 alkyl and R.sub.12 is the same as R.sub.11, or R.sub.11 and R.sub.12 together form cyclopentane or cyclohexane, and R.sub.13 is:(a) phenyl substituted 1 to 5 times with C.sub.3 -C.sub.7 secondary alkyl or C.sub.4 -C.sub.7 ; tertiary alkyl, or(b) selected from the group consisting of naphthyl, anthryl, and phenanthryl optionally substituted 1 to 5 times with C.sub.3 -C.sub.7 secondary alkyl or C.sub.4 -C.sub.7 tertiary alkyl groups,R.sub.10 is C.sub.6 -C.sub.10 alkyl, aryl or alkyl aryl,and Y is H, F or Cl,are disclosed. These processes can be used to make optically enhanced and optically pure forms of the compounds, which are useful in the making of camptothecin and analogs thereof.

Abstract: A foldable bed comprising a frame including a body section, a cavity section, a seat section, and a foot section, each of which includes a pair of side rails, each of which are pivotally interconnected and which are movable between an unfolded position and a folded position, a mattress carried by the frame and movable therewith between the unfolded and folded positions, wherein in the folded position the mattress is folded upon itself to define an upper support surface, and interconnecting means for pivoting the frame sections between the unfolded position and the folded position, wherein in the unfolded position the body section, the cavity section, the seat section, and the foot section are serially and horizontally aligned, and the side rails of the sections are positioned along respective opposite sides of and generally below the mattress, and in the folded position, the body section is generally horizontal, the seat section overlies the body section, the cavity section extends substantially vertically be

Abstract: Compounds of Formula I ##STR1## are made in accordance with the following scheme: ##STR2## wherein R may be loweralkyl; R.sub.t may be H, loweralkyl, loweralkoxy, or halo: R.sub.2, R.sub.3, R.sub.4, and R.sub.5 may each independently be H, amino, hydroxy, loweralkyl, loweralkoxy, loweralkylthio, di(loweralkyl)amino, cyano, methylenedioxy, formyl, nitro, halo, trifluoromethyl, aminomethyl, azido, amido, hydrazino, or any of the twenty standard amino acids bonded to the A ring via the amino-nitrogen atom; Y is H and W and X are halogen. Also disclosed are novel processes for making starting materials for the scheme given above, and novel intermediates employed in these processes.

Abstract: Rods for use in the manufacture of smoking products are provided using a rod-making apparatus. The apparatus includes (a) an unwind unit for continuously supplying a material having a continuous integrity; (b) a rod-forming unit for forming a rod-like composite of the supplied material; (c) a constriction member for constricting the rod-like composite, the constriction member including (i) a material-contacting surface and (ii) a reservoir for supplying an amount of liquid to at least a portion of the material-contacting surface; and (d) a rod-making unit for receiving the rod-like composite and for circumscribing the rod-like composite with wrapping material thereby forming a continuous rod.

Abstract: Compounds of Formula I ##STR1## are made in accordance with the following scheme: ##STR2## wherein R may be loweralkyl; R.sub.1 may be H, loweralkyl, loweralkoxy, or halo; R.sub.2, R.sub.3, R.sub.4, and R.sub.5 may each independently be H, amino, hydroxy, loweralkyl, loweralkoxy, loweralkylthio, di(loweralkyl)amino, cyano, methylenedioxy, formyl, nitro, halo, trifluoromethyl, aminomethyl, azido, amido, hydrazino, or any of the twenty standard amino acids bonded to the A ring via the amino-nitrogen atom; Y is H and W and X are halogen. Also disclosed are novel processes for making starting materials for the scheme given above, and novel intermediates employed in these processes.

Abstract: A concrete floatation module adapted for use as a floating dock, breakwater, and the like. The module includes thickened portions of concrete extending lengthwise in a concrete shell preferably in the corner portions of the shell. The shell surrounds a buoyant foam core which may be used as a molding core for the floatation module. The thickened lengthwise extending portions of concrete include integrally molded tubular liners for creating passageways through the module for the passage therethrough of an interconnecting means, such as a steel cable. The tensioned steel cables maintain the modules in compression in an end-to-end relation thereby forming a single monolithic structure. Widthwise extending liners may also be provided to facilitate the interconnecting of laterally extending branches of modules. The floatation modules may be readily formed on-site by integrally molding the buoyant foam core and tubular liners in the concrete shell.

Abstract: A drinking water distribution system for poultry is disclosed providing poultry such as turkeys and chickens with fresh clean drinking water. The system utilizes gravity feed to distribute water from a reservoir through a conduit to a series of water cups connected to the conduit in open communication with the conduit and extending upwardly therefrom. The conduit and reservoir are suspendingly supported above the floor of the poultry house by cables depending downwardly from overhead portions of the poultry house and connected to a winch so as to be easily raised to a suitable height to accommodate growth of the poultry. The system further monitors the water temperature and if the temperature of the water gets too warm, the system replaces it with water of a lower temperature. The invention further includes an arrangement for periodically purging and cleansing the system by replacing the drinking water with liquid disinfectant for a predetermined dwell period.

Abstract: A rapid recovery gas water heating system having a water storage tank, a gas water heater separate from the storage tank and having a compact heat exchanger for the flow of water therethrough from the storage tank, a water pump for pumping of water from lower regions of the storage tank into and through the heat exchanger and back into the storage tank, and a thermostat having water temperature sensing means positioned in the storage tank and serving for actuating the water pump and the gas water heater in response to the temperature of the water in the storage tank falling below a predetermined temperature value.

Abstract: A woven terry fabric having tucks formed therein for obtaining novel aesthetic effects in the fabric and the method of weaving such fabrics.

Abstract: This invention relates to an apparatus for molding slotted concrete floor sections. The apparatus forms the concrete floor sections in an inverted position so as to avoid the need for hand finishing of the upper surface of the molded concrete floor sections. The apparatus comprises a base, opposing pairs of interconnected upstanding side and end walls connected to the base and a plurality of elongate spaced apart and substantially parallel ridges connected to and projecting upwardly from the base. Attached to and overlying the ridges are a plurality of elongate keystone shaped dividers removably mounted on and extending upwardly from the ridges with the upper surface being in a substantially common plane with the upper surfaces of the side and end walls.

Abstract: An apparatus for melting and pouring metal alloys includes a vacuum melt furnace having a melt chamber to receive and melt metal in a vacuum. A valve cooperates with a pour opening located at the bottom of the furnace. The valve includes an upper stationary nozzle portion formed substantially from refractory material and having an orifice aligned with the pour opening. A lower nozzle portion having an orifice therethrough is mounted adjacent and below the upper nozzle portion for slidable movement along a lower face of the upper stationary nozzle portion. The valve is opened and closed by slidably moving the lower nozzle orifice in and out of alignment with the upper nozzle orifice. An induction heating coil substantially surrounds the upper stationary nozzle portion.

Abstract: A shipping bag is disclosed for containers of potentially biohazardous materials wherein the bag has liquid impervious outer panels and pads within the bag to absorb any liquid should the container rupture. In the event of rupture of the container, persons handling such bags will be protected from contact with such liquid by the combined effects of absorbing the liquid and containing the liquid within the fluid impervious outer panels of the bag.