Abstract: The present invention provides a novel enzyme which de-O-acetylates glucuronoxylomannan of Cryptococcus neoformans and a gene encoding such enzyme. Also provided are applications of such enzyme in treating cryptococcosis.
Type:
Grant
Filed:
August 25, 2000
Date of Patent:
September 4, 2001
Assignee:
Research Development Foundation
Inventors:
Anne C. Savoy, Sherri L. Bloomer, Thomas R. Kozel