Abstract: The present invention provides a method of recovering cellular functions in cells following injury, comprising the step of contacting said cells with collagen IV or a natural or mutated fragment thereof. Further provided is a pharmaceutical composition, comprising a therapeutically effective amount of collagen IV or a natural or mutated fragment thereof and a topically acceptable carrier.
Type:
Grant
Filed:
March 20, 2003
Date of Patent:
February 27, 2007
Assignee:
The University of Arkansas for Medical Sciences
Abstract: The present invention provides a TADG-12 protein and a DNA fragment encoding such protein. Also provided is a vector/host cell capable of expressing the DNA. The present invention further provides various methods of early detection of associated ovarian and other malignancies, and of interactive therapies for cancer treatment by utilizing the DNA and/or protein disclosed herein.
Type:
Grant
Filed:
March 2, 2000
Date of Patent:
September 25, 2001
Assignee:
The Board of Trustees of the University of Arkansas
Inventors:
Timothy J. O'Brien, Lowell J. Underwood