Abstract: The invention provides pharmaceutical compositions for the treatment or prevention of the toxic effects of therapeutic agents and methods of treating or preventing such toxicity using a toxicity reducing amount of N-acetylcysteine either alone or in combination with a therapeutically effective amount or, to achieve its therapeutic advantages, an amount larger than what is customarily given as a therapeutically effective amount, of a therapeutic agent.
Type:
Grant
Filed:
April 11, 2001
Date of Patent:
May 20, 2003
Assignee:
The Board of Trustees of the Leland Stanford Junior
University
Inventors:
Leonard A. Herzenberg, Leonore A. Herzenberg, Stephen C. De Rosa, James Andrus