Patents Represented by Law Firm Bierman & Muserlian
  • Patent number: 6783986
    Abstract: Proteins having the activity of saccharose phosphate synthetase (SPS) and a process for obtaining the same.
    Type: Grant
    Filed: April 26, 1995
    Date of Patent: August 31, 2004
    Assignee: Aventis Crop Sciences GmbH
    Inventors: Charles Van Assche, Danielle Lando, Jean Michel Bruneau, Toni Alois Voelker, Monica Gervais
  • Patent number: 6670504
    Abstract: The invention relates to a method for producing acetic acid from ethane and oxygen on a fixed bed catalyst, characterized in that a reactor cascade with an oxygen feed between the reactor levels is used. This particularly advantageous method provides high conversion rates, highly pure acetic acid and low ethylene and carbon monoxide formation.
    Type: Grant
    Filed: November 10, 1999
    Date of Patent: December 30, 2003
    Assignee: Hoechst Research & Technology Deutschland GmbH & Co. KG
    Inventors: Holger Borchert, Uwe Dingerdissen, Ranier Roesky
  • Patent number: 6637389
    Abstract: The invention relates to an electrically driven device (1) for the angular adjustment of a shaft relative to its drive (2), said device comprising an eccentric gearing that comprises at least one internally geared wheel and one spur gear that meshes with the internally geared wheel and can be driven by an electrically rotatable eccentric shaft. The considerable structural complexity and space requirement as also the noise level of prior art devices is reduced by the fact that the internally geared wheel is configured as a first and a second internally geared wheel (6, 9), and the spur gear is configured as a first and a second spur gear (16, 17) that have the same number of teeth and are rotatable in opposite directions, the internally geared wheels (6, 9) are connected to the drive (2) and the spur gears (16, 17) are connected to the camshaft and can be driven through a double eccentric shaft (20) comprising identical eccentrics (18, 19) arranged offset at 180° to each other.
    Type: Grant
    Filed: October 26, 2001
    Date of Patent: October 28, 2003
    Assignee: INA Walzlager Schaeffler oHG
    Inventors: Jens Schafer, Hans Fleischer
  • Patent number: 6630461
    Abstract: A method for treating neurodegenerative diseases in a warm-blooded animal comprising administering to a warm-blooded animal in need thereof an amount of a compound of the formula wherein A selected from the group consisting of hydrogen and wherein the substituents are defined as set forth in the specification.
    Type: Grant
    Filed: June 15, 2001
    Date of Patent: October 7, 2003
    Assignee: Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Pierre Etienne Chabrier de Lassauniere, Serge Auvin, Dennis Bigg, Michel Auguet, Jeremiah Harnett
  • Patent number: 6579824
    Abstract: The invention relates to a catalyst which contains palladium and/or compounds thereof, gold and/or compounds thereof, alkali metal compounds and at least one lanthanoid metal and/or compounds thereof. The invention also relates to the utilization of the catalyst in order to produce vinyl acetate from acetic acid, ethylene and oxygen or gases containing oxygen.
    Type: Grant
    Filed: July 20, 2000
    Date of Patent: June 17, 2003
    Assignees: Celanese Chemicals Europe GmbH, Celanese International Corporation
    Inventors: Bernhard Herzog, Tao Wang, Toan Nicolau
  • Patent number: 6566366
    Abstract: Compounds of the formula and salts thereof wherein the substituents are defined as in accordance with the specification useful for the treatment of tumor growth, osteoporosis, inflammation and cardiovascular disorders.
    Type: Grant
    Filed: March 6, 2001
    Date of Patent: May 20, 2003
    Assignees: Aventis Pharma Deutschland GmbH, Genentech, Inc.
    Inventors: Karl-Heinz Scheunemann, Jochen Knolle, Amuschirwan Peyman, David William Will, Denis Carniato, Jean-Francois Gourvest, Thomas Gadek, Robert McDowell, Sarah Catherine Bodary, Robert Andrew Cuthbertson
  • Patent number: 6548664
    Abstract: The invention concerns compounds of formula (I) in SR configuration or in the form of a SR+SS mixture, wherein R represents a hydrogen atom, an alkyl or aralkyl radical containing up to 18 carbon atoms, the amine function being free or protected. The compounds can be used for preparing active principles for medicines.
    Type: Grant
    Filed: October 31, 2000
    Date of Patent: April 15, 2003
    Assignee: Aventis Pharma S.A.
    Inventors: Colette Colladant, Veronique Cro-cq, John Patrick Larkin, Patrick Roussel
  • Patent number: 6546858
    Abstract: A marking machine with fixed motors comprising a first electric and fixed motor for transmitting motion to a first head sliding on a first guide in the OX direction, a second electric and fixed motor for transmitting motion to a working head sliding on a second guide in the OY direction; wherein a support is integral with the first head and the second guide; the first and second motors being controlled so as to create a differential motion between the two motors sufficient to effect displacement in the OY direction.
    Type: Grant
    Filed: October 26, 2000
    Date of Patent: April 15, 2003
    Assignee: Proyectos y Fabricacion Electronica S.A.
    Inventor: Francisco Azpiroz Villar
  • Patent number: 6547052
    Abstract: A synchronizing ring (1, 8, 13) having a substantially cone-shaped annular body (2, 10, 14, 21) is made by shaping out of sheet metal and is provided on its end section (2b) having the small cone-diameter, with stops (5, 6, 7) that extend in radial direction beyond the contour of the outer peripheral surface of the annular body (2, 10, 12, 14).
    Type: Grant
    Filed: May 30, 2001
    Date of Patent: April 15, 2003
    Assignee: Ina Walzlager Schaeffler oHG
    Inventors: Josef Schwuger, Rudolf Sinner, Hartwig Waldert
  • Patent number: 6545136
    Abstract: This invention relates to a process for producing a desulfated polysaccharide, which comprises reacting a sulfated polysaccharide having a saccharide in which a primary hydroxyl group is sulfated, as a constituent sugar, with a silylating agent represented by the following formula (I) wherein R1s are the same or different and each represent a hydrogen atom or a halogen atom, R2 represents a lower alkyl group, and R3s are the same or different and each represent a lower alkyl group, an aryl group or a halogen atom, and a desulfated heparin obtained by this production process.
    Type: Grant
    Filed: June 27, 2000
    Date of Patent: April 8, 2003
    Assignee: Seikagaku Corporation
    Inventors: Saburo Hara, Keiichi Yoshida, Masayuki Ishihara
  • Patent number: 6544977
    Abstract: Two new crystalline forms of 1S-[1alpha(2S*,3R*), 9alpha]6,10-dioxo-N-(2-ethoxy-5-oxo-tetrahydro-3-furanyl)-9 [[(1-isoquiinolyl)carbonyl]amino]octahydro-6H-pyridazino[1,2-a][1,2]diazepin-1-carboxamide (anhydrous or hydrated), their preparation process and the pharmaceutical compositions containing them.
    Type: Grant
    Filed: November 20, 2000
    Date of Patent: April 8, 2003
    Assignee: Aventis Pharma S.A.
    Inventors: Jean-Yves Godard, Valerie Rognon
  • Patent number: 6544703
    Abstract: An electrophotographic photoreceptor having an interlayer between the electrically conductive base body and the photosensitive layer. The electrophotographic photoreceptor an aluminum-evaporated surface and contact potential difference of said interlayer with respect to the aluminum-evaporated surface of the photoreceptor is at least +0.175 V.
    Type: Grant
    Filed: March 13, 2002
    Date of Patent: April 8, 2003
    Assignee: Konica Corporation
    Inventor: Hirofumi Hayata
  • Patent number: 6544995
    Abstract: The invention relates to the use of cysteine derivatives for preparing a medicament intended to treat diseases which result from the formation of the heterotrimeric G protein. These diseases include in particular diseases linked to the following biological functions or disorders: smell, taste, perception of the light, neurotransmission, neurodegeneration, endocrine and exocrine gland functions, autocrine and paracrine regulation, arterial tension, embroygenesis, benign cell proliferation, oncogenesis, viral infection, immunological functions, diabetes, obesity, and benign and malign proliferative diseases. Said cysteine derivatives include in particular: bis-1,1′-[7-(2-amino-1-oxo-3-thiopropyl)-8-(cyclohexylmethyl)-2-(2-methoxyphenyl)-5,6,7,8-tetrahydroimidazo[1.2a]pyrazine disulphide (I), and bis-1,1′-7-(2-amino-1-oxo-3-thiopropyl-(2-(1-naphtyl)-8-(2-methylpropyl)-5,6,7,8-tetrahydroimidazo[1.2a]pyrazin-7-yl)disulphide (II).
    Type: Grant
    Filed: January 4, 2001
    Date of Patent: April 8, 2003
    Assignee: Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Grégoire Prevost, Marie-Odile Lonchampt, Thomas Gordon
  • Patent number: 6541464
    Abstract: Compounds of the formula Where the substituents are defined in the application.
    Type: Grant
    Filed: February 14, 2002
    Date of Patent: April 1, 2003
    Assignee: Aventis Pharma S.A.
    Inventors: Yamina Bouali, Francois Nique, Jean-Georges Teutsch, Patrick Van De Velde
  • Patent number: 6537787
    Abstract: A process for obtaining polyunsaturated fatty acid concentrates comprising subjecting a fish oil containing docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), to a selective enzymatic hydrolysis in position 1, 3 or 2, to obtain a mixture of free fatty acids, monoglycerides and diglycerides, separating the constituents of this mixture, collecting the free fatty acids which are purified by crystallization from urea, to increase the EPA and DHA content, decomplexing the isolated fatty acids by an inter-esterification between the free fatty acids concentrated into polyunsaturated fatty acids and the crude oil, in the presence of a lipase specific for position or steric hindrance, to obtain a mixture enriched with polyunsaturated fatty acid triglycerides which is separated and freed from the free fatty acids and a process for enrichment with polyunsaturated fatty acids (EPA, DHA) of phospholipids by an enzymatic route, as well as in the synthesis of monoacylglycerols of polyunsaturated fatty acids of the
    Type: Grant
    Filed: March 13, 1998
    Date of Patent: March 25, 2003
    Inventor: Gildas Breton
  • Patent number: 6537743
    Abstract: An silver halide photothermographic light sensitive material comprising a support having thereon a undercoating layer and a photographic light-sensitive layer containing a light-sensitive silver halide, and organic silver salt, a reducing agent and a binder, wherein the undercoating layer contains fine particles having a mean primary particle size of 0.01 to 1.6 &mgr;m and satisfying the following equation, 1≦(r2/r1)≦1.4 wherein r1 and r2 are respectively an inscribed circle radius and a circumscribed circle radius of each of projected images of the fine particles obtained by a microscope, and (r2/r1) is an average value of r2/r1 of projected images of 500 fine particles randomly selected from the whole fine particles.
    Type: Grant
    Filed: December 7, 2001
    Date of Patent: March 25, 2003
    Assignee: Konica Corporation
    Inventors: Yasuyuki Motokui, Kenji Ohnuma, Hidetoshi Ezure, Takayuki Sasaki, Ichiro Kudo
  • Patent number: 6533139
    Abstract: A splash-proof lid assembly is a substantially planar unit which is made up of a disc and a bottom section that is rotatably connected to the disc. By rotating the bottom section to the underside of the disc, a tube is formed which allows for drinking from a cup once the lid is placed on the cup.
    Type: Grant
    Filed: September 20, 2001
    Date of Patent: March 18, 2003
    Inventor: Temo Lukacevic
  • Patent number: 6534268
    Abstract: The present invention provides a method for exploring low molecular weight compounds which regulate positively or negatively the expression of human BMP-7 with reference to a reporter activity by using 5′ upstream region gene containing the human BMP-7 promoter and an animal cell introduced with the vector that has been connected to an appropriate reporter gene. The low molecular weight compounds and their derivatives obtained by the present method have morphogenetic activity or inhibiting activity for bone and cartilage through the expression of the human BMP-7 and are useful as preventive or therapeutic agents for cartilage and bone diseases. Furthermore, the low molecular weight compounds and their derivatives are useful as therapeutic agents for kidney diseases.
    Type: Grant
    Filed: November 30, 2000
    Date of Patent: March 18, 2003
    Assignee: Aventis Pharma S.A.
    Inventors: Shinji Kawai, Takeyuki Sugiura
  • Patent number: 6534515
    Abstract: A compound selected from the group consisting of all possible isomers or racemates of a compound of the formula wherein the various substituents are as defined in the specification and its non-toxic, pharmaceutically acceptable salts with acids or bases having anti-anoxic, anti-ischemic and neuronal protective anti-depressant activities.
    Type: Grant
    Filed: April 15, 1994
    Date of Patent: March 18, 2003
    Assignee: Aventis Pharma S.A.
    Inventors: François Clemence, Jean-Luc Haesslein, Claude Oberlander
  • Patent number: 6534251
    Abstract: A silver salt photothermographic dry imaging material comprising a support having thereon a photosensitive layer comprising silver aliphatic carboxylate grains and photosensitive silver halide grains, a reducing agent for silver ions, a binder and a cross-linking agent, wherein the photothermographic material has a silver coverage of 1.0 to 1.7 g/m2; the photosensitive silver halide grains have a mean grain size of 0.03 to 0.055 &mgr;m and a degree of grain size dispersity of not more than 30%; after the dry imaging material has been subjected to photothermographic processing at a temperature of 100 to 200° C. for 5 to 50 seconds, the photosensitive layer exhibits a thermal transition temperature of 46 to 200° C.
    Type: Grant
    Filed: March 6, 2002
    Date of Patent: March 18, 2003
    Assignee: Konica Corporation
    Inventors: Keiko Maeda, Tetsuo Shima