Patents Represented by Law Firm Bierman & Muserlian
  • Patent number: 5770579
    Abstract: Compounds of the formula ##STR1## wherein X and X' form C.dbd.O or C.dbd.NOR, R is selected from the group consisting of hydrogen, heterocycle, alkyl, alkenyl, alkynyl, all optionally substituted, ##STR2## R.sub.a and R.sub.b are hydrogen or a hydrocarbon group or form together with the nitrogen a heterocycle, or with A forms a 9-N, 11-O ring, and X' is hydrogen, --Y and Y' have the same definition as X and X', b is hydrogen or OR.sub.4, R.sub.4 is hydrogen or forms together with A a carbonate or a carbamate, A forms with C a double bond or A is OR'.sub.4, R'.sub.4 is hydrogen or forms together with B a carbonate or ##STR3## R.sub.2 is alkyl or --CONH.sub.2, --CONHCOR.sub.11 or --CONHSO.sub.2 R.sub.11, R.sub.11 is a hydrocarbon up to 18 carbon atoms, R.sub.3 is hydrogen, ##STR4## and Z is hydrogen or a carboxylic acid remainder and their non-toxic, pharmaceutically acceptable acid addition salts, their preparation and intermediates useful as antibiotics.
    Type: Grant
    Filed: January 25, 1995
    Date of Patent: June 23, 1998
    Assignee: Roussel Uclaf
    Inventors: Constantin Agouridas, Yannick Benedetti, Jean-Fran.cedilla.ois Chantot, Alexis Denis, Claude Fromentin, Odile Le Martret
  • Patent number: 5674718
    Abstract: Nucleic acids segment comprising a nucleotide coding sequence for Pseudomonas testosteroni .DELTA.1-dehydrogenase or an homologous or complementary nucleotide sequences thereof.
    Type: Grant
    Filed: February 17, 1994
    Date of Patent: October 7, 1997
    Assignee: Roussel Uclaf
    Inventors: Yvon Michel-Briand, Patrick Plesiat
  • Patent number: 5669342
    Abstract: A device (1) for simultaneous actuation of at least two gas exchange valves (2) of an internal combustion engine comprising a bridge-type cam follower (3) arranged in driving relationship between a camshaft and the gas exchange valves (2) and serving to directly transmit a stroke motion caused by a control cam (4) of the camshaft to the gas exchange valves (2), said cam follower (3) being guided by guiding means (18,19) for vertical displacement in a cylinder head and comprising a cam contacting element (31) on which the control cam (4) runs, characterized in that the cam contacting element (31) in the cam follower (3) is displaceable relative to the cam follower (3) so that the cam follower (3) can be uncoupled from a stroke-transmitting motion of the control cam (4).
    Type: Grant
    Filed: February 28, 1996
    Date of Patent: September 23, 1997
    Assignee: INA Walzlager Schaeffler KG
    Inventor: Walter Speil
  • Patent number: 5627201
    Abstract: A compound of the formula ##STR1## wherein R.sub.1 is selected from the group consisting of --CN, --NO.sub.2 and halogen, R.sub.2 is --CF.sub.3 or halogen, --A--B-- is selected from the group consisting of ##STR2## X is --O-- or --S--, R.sub.3 is selected from the group consisting of hydrogen, alkyl, alkenyl and alkynyl of up to 12 carbon atoms, aryl and aralkyl of up to 12 carbon atoms, all optionally substituted with at least one member of the group consisting of --OH, halogen, --SH, --CN, acyl and acyloxy of up to 7 carbon atoms, --aryl, --O--aryl, --O--aralkyl --S-- aryl of up to 12 carbon atoms the aryl and aralkyl being optionally substituted with a member of the group consisting of halogen, --CF.sub.3, alkyl, alkoxy, alkenyl, alkenyloxy, alkynyl and alkynyloxy with the sulfur being optionally oxidized to sulfone or sulfoxide, free, esterified, amidified or salified carboxy, --NH.sub.
    Type: Grant
    Filed: January 13, 1995
    Date of Patent: May 6, 1997
    Assignee: Roussel Uclaf
    Inventors: Martine Gaillard-Kelly, Francois Goubet, Daniel Philibert, Jean-Georges Teutsch
  • Patent number: 5616743
    Abstract: A compound having the formulae selected from the group consisting of ##STR1## wherein R.sub.2 and R.sub.3 are hydrogen or R.sub.2 is fluorine and R.sub.3 is formyloxy or acetyloxy, the dotted line in 9(11) position indicates an optional double bond and the dotted line in position 16(17) indicates an optional double bond ##STR2## is a 3-keto-.DELTA..sup.4 -system or 3-keto-.DELTA..sup.1,4 -system or 3-OR.sub.4 -.DELTA..sup.5 -system, R.sub.4 is hydrogen or a protector group of hydroxy, R is --CH.sub.3, --CH.sub.2 OH or --CH.sub.2 --OR', R' is a hydroxy protector group and R'.sub.1 is selected from the group consisting of methyl, a branched alkyl of 5 to 8 carbon atoms not possessing hydrogen in the .beta.-position, aryl of up to 10 carbon atoms and benzyl, hetroaryl of up to 10 carbon atoms and at least one heteroatom selected from the group consisting of nitrogen, sulfur and oxygen, with the exception of the compounds of formula Vc in which R is methyl, R.sub.2 and R.sub.3 are hydrogen or R.sub.2 and R.sub.
    Type: Grant
    Filed: January 13, 1995
    Date of Patent: April 1, 1997
    Assignee: Roussel UCLAF
    Inventors: Jean Boivin, Samir Zard, Christine Chauvet
  • Patent number: 5614614
    Abstract: Novel intermediates for the preparation of the compounds of Formula I wherein the substituents are as defined in the specification.
    Type: Grant
    Filed: February 21, 1995
    Date of Patent: March 25, 1997
    Assignee: Roussel Uclaf
    Inventors: Constantin Agouridas, Alain Bonnefoy, Jean-Francois Chantot, Alexis Denis, Odile Le Martret
  • Patent number: 5598815
    Abstract: A roller lever (1) of a casting material configured as a finger lever for a valve drive of an internal combustion engine and comprising a first end portion (2) and a second end portion (4) connected to each other by side walls (7, 8) whose central portions (6) define a free space (9) in which a rotatably mounted supporting roller (10) is guided, said side walls (7, 8) comprising, in a region of the supporting roller (10), circular ring-shaped running surfaces (13, 14) facing the free space (9), the roller lever (1) further comprising a mold parting line (15) resulting from manufacture in a casting mold having a mold parting, characterized in that the mold parting line (15) between two halves of the casting mold extends outside of the running surface (13, 14) along a peripheral contour (16) of the running surfaces (13, 14) and a roller lever of a casting material configured as a rocker arm for a valve drive of an internal combustion engine, one end region of the roller lever being a fork-shaped region for rece
    Type: Grant
    Filed: May 2, 1996
    Date of Patent: February 4, 1997
    Assignee: Ina Walzlager Schaeffler KG
    Inventor: Steffen Hertrich
  • Patent number: 5599830
    Abstract: The invention relates to the products: ##STR1## in which: R.sub.1 =alkyl, alkenyl, alkynyl, alkylthio,R.sub.2B, R.sub.3B representing:hydrogen, mercapto, formyl, acyl, carboxy nitro, cyano,--PO.sub.3 (R).sub.2, R representing hydrogen, alkyl, aryl, amino or carbamoyl,the R.sub.4B radicals; ##STR2## n=0 to 2 X'=arylR.sub.4B either represents --(CH.sub.2).sub.m1 --S(O).sub.m2 --X--R.sub.10, m1=0 to 4, m2=0 to 2either m1 is different from 0, X--R.sub.10 represents amino, or whatever m1 is, X represents a single bond or --NH--, --NH--CO--, --NH--CO--NH--,R.sub.10 =alkyl, alkenyl or aryl, or hydrogen, alkyl, alkenyl, alkynyl, acyl or amino,--S--S--R.sub.4B ', R.sub.4B ' represents R.sub.4B except for amino and alkoxy, and one of R.sub.2B and R.sub.3B represents --OR.sub.4B : ##STR3## m=0 to 2, Y.sub.B ---Y.sub.1B --B--Y.sub.2B,Y.sub.1B =aryl,B=a single bond or --CO--, --O--, --NH--CO--, --CO--NH--, --O--O--(CH.sub.2).sub.p --,p=1 to 3,Y.sub.
    Type: Grant
    Filed: January 9, 1995
    Date of Patent: February 4, 1997
    Assignee: Roussel Uclaf
    Inventors: Jean C. Caille, Alain Corbier, Michel Fortin, Gilles Hamon, Simone Jouquey, Jean P. Vevert
  • Patent number: 5597243
    Abstract: The invention concerns a radial rolling bearing having cylindrical rolling elements which roll between an inner and an outer ring while individual spacers are disposed between every two adjacent rolling elements, the spacers comprising, on both sides of their central longitudinal plane, contact surfaces while being guided during rotation of the radial rolling bearing by one of their end sections on a raceway of the inner or the outer ring.
    Type: Grant
    Filed: April 6, 1995
    Date of Patent: January 28, 1997
    Assignee: Ina Walzlager Schaeffler KG
    Inventors: Theodor Kaiser, Roland Lippert, Cornelius Hartmann, Horst D. Kohler, Ernst Mayer, Bruno Scherb
  • Patent number: 5595897
    Abstract: The invention concerns a complex between at least one negatively charged nucleic acid and at least one positively charged polymeric conjugate, the link between the nucleic acid and the polymeric conjugate being electrostatic in nature, the polymeric conjugate containing a polymer formed from monomer components having free NH.sub.3.sup.+ functions of the aforementioned components and being as follows:--the free NH.sub.3.sup.+ functions from the aforementioned components are substituted in a ratio of at least 10%, advantageously from 45% to 70%, particularly 60%, by noncharged residues leading to a reduction of positive charges in comparison to the same nonsubstituted polymeric conjugate, facilitating the release of nucleic acid by the dissociation of the complex,--the aforementioned residues possess in addition the following properties:.fwdarw.they contain at least one hydroxyl group,.fwdarw.they do not correspond to a recognition signal recognized by a cellular membrane receptor,--the free NH.sub.3.sup.
    Type: Grant
    Filed: August 10, 1994
    Date of Patent: January 21, 1997
    Assignee: I.D.M. Immuno-Designed Molecules
    Inventors: Patrick Midoux, Patrick Erbacher, Annie-Claude Roche-Degremont, Michel Monsigny
  • Patent number: 5595149
    Abstract: A method of leakproof first filling of a hydraulic valve actuating tappet (1) with hydraulic oil,a) comprising almost completely filling the central oil reservoir (7) together with a high pressure chamber (18) situated axially between the bottom (11) of the pressure piston (10) and the guide sleeve (5), and the annular oil reservoir (17), with hydraulic oil, andb) filling at least the supply bore (19) leading to the annular oil reservoir (17), with a lubricating grease or a pasty material (20) which is flow-resistant at ambient temperature.
    Type: Grant
    Filed: January 22, 1996
    Date of Patent: January 21, 1997
    Assignee: Ina Walzlager Schaeffler KG
    Inventors: Walter Speil, Dieter Schmidt
  • Patent number: 5594099
    Abstract: A modified resinate prepared by reactingA) rosins or rosin acids withB) aldehyde components and optionallyC) .alpha.,.beta.-olefinically unsaturated carboxylic acids or anhydrides thereof, subsequently reacting the resultant adduction products withD) phenols and optionallyE) alcohols containing at least two hydroxyl groups and subsequently forming resinates withF) basic compounds of divalent metals, useful as resin binders of high viscosity in low solid printing inks for intaglio printing of illustrations.
    Type: Grant
    Filed: March 31, 1995
    Date of Patent: January 14, 1997
    Assignee: Hoechst Aktiengesellschaft
    Inventor: Albert Bender
  • Patent number: 5591495
    Abstract: Copolyamide barrier layers which are durable hot-water stable and transparent. The copolyamide is amorphous and partially aromatic, and comprises(a) 50 molar parts of substituted or unsubstituted aromatic dicarboxylic acids which are replaced by up to 60% by weight of at least one additional dicarboxylic acid selected from the group consisting of cycloaliphatic dicarboxylic acids having 8 to 24 carbon atoms, araliphatic dicarboxylic acids having 8 to 18 carbon atoms, and mixtures thereof, and (b) 50 molar parts of hexamethylene diamine, which is replaced by up to 60% by weight of at least one additional diamine, selected from the group consisting of substituted or unsubstituted aliphatic diamines having 4 to 20 carbon atoms, substituted cycloaliphatic diamines having 6 to 24 carbon atoms, araliphatic diamines having 8 to 18 carbon atoms, and mixtures thereof,the acid groups and amino groups being present substantially in equimolar proportions.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: January 7, 1997
    Assignee: EMS-INVENTA AG
    Inventors: Hans D. Torre, Manfred Hewel
  • Patent number: 5589999
    Abstract: A recording head (9) and a playback head (8) each provided with a separate actuating device, a storage hopper (33) between the heads (8, 9) receives the tape (2) fed out by the recording head (9) and stores in loose, random folds when the tape region facing the recording head (9) is at a distance from the tape region facing the reading head (8), two reels interacting with respective heads are arranged in a cassette (1), when the cassette is inserted, a roller (3) grips the tape and pre-engages it into the storage hopper (33), which apparatus enables time-delay playback without causing undesirable congestion or tape installation problems.
    Type: Grant
    Filed: December 28, 1994
    Date of Patent: December 31, 1996
    Inventors: Marc Hayat, Max de Ferran
  • Patent number: 5580937
    Abstract: Curable binder composed ofA. a polyepoxide andB. a carboxyl group-containing polymer which is obtained by reacting a carboxy-functional polyester b1 with substoichiometric amounts of an epoxy compound b2.The binder according to the invention has a high reactivity coupled with good storage stability.
    Type: Grant
    Filed: December 16, 1992
    Date of Patent: December 3, 1996
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Uwe Neumann, Michael Hoenel, Paul Oberressl, Marion Keller
  • Patent number: 5578388
    Abstract: A membrane electrochemical cell, in particular a fuel cell, of an improved type comprising a multiplicity of cell elements, each element made up of bipolar plates, current collectors, electrodes and membranes, wherein the function of electric current transmission through the cell elements, the release of heat towards the outside environment, the distribution of electric current to the electrodes and membranes, the removal of heat from the electrodes and membranes and the distribution of the reactants and products are performed by distinct components, in particular bipolar plates for the first two and porous electroconductive collectors for the others. The bipolar plates may have flat surfaces without grooves and are preferably manufactured with aluminum, titanium or alloys thereof, through cheap mass productions techniques; the bipolar plates are used together with collectors provided with deformability, residual resiliency and high porosity.
    Type: Grant
    Filed: June 1, 1995
    Date of Patent: November 26, 1996
    Assignee: De Nora Permelec S.p.A.
    Inventors: Giuseppe Faita, Claudio Mantegazza
  • Patent number: 5574194
    Abstract: The compound 2,6-bis-(trifluoromethyl)-benzyl alcohol which is useful as an intermediate to compounds having pesticidal properties.
    Type: Grant
    Filed: October 6, 1995
    Date of Patent: November 12, 1996
    Assignee: Roussel Uclaf
    Inventors: Didier Babin, Marc Benoit, Jean-Pierre Demoute
  • Patent number: 5567060
    Abstract: A differential gearing comprising a differential case (2) mounted in a gearbox casing (1) and connected via a crown wheel (6) to a drive pinion (4) of a third motion shaft (5), axle shafts (9) being mounted in the differential case (2), characterized in that the axle shafts (9) are mounted in the differential case (2) on a clearance-free or pre-tensioned rolling bearing (11).
    Type: Grant
    Filed: February 8, 1995
    Date of Patent: October 22, 1996
    Assignee: Ina Walzlager Schaeffler KG
    Inventors: Wolfgang Steinberger, Rudolf Folk, Reinhart Malik
  • Patent number: 5564995
    Abstract: A planetary transmission comprising a planet carrier (6) connected rotationally fast to a driving shaft (3), a planet gear (7) of which planet carrier (6) is simultaneously in mesh with an annulus (9) fixed on a housing (1,2) and with a sun gear (10) connected rotationally fast to a driven shaft (12) arranged concentric with the driving shaft (3), each of the driving shaft (3) and the driven shaft (12) being mounted for rotation relative to the housing (1,2) on at least one bearing (16,17) and outer and inner rings (22,25 31 34) of said bearings (16,17) being seated on bearing seats (5,14,11,15), characterized in that at least one of two bearing seats (5,14,11,15) of each bearing (16,17) comprises at an axial end thereof, a resilient projection (19,24,27,32) engaging by elastic reverse deformation, an end face of the inner or outer bearing ring (22,25,31,34) seated thereon.
    Type: Grant
    Filed: March 17, 1995
    Date of Patent: October 15, 1996
    Assignee: Ina Walzlager Schaeffler KG
    Inventors: Ulrich Roder, Sigurd Wilhelm, Werner Hehn, Uwe Hammerl, Doris Greiner, Wolfgang Hentschke, Udo Reinhardt
  • Patent number: 5565508
    Abstract: Aqueous synthetic resin dispersions comprising A) an ionic resin, preferably a cationic resin, B) a blocked polyisocyanate and C) a polymer of at least one ethylenically unsaturated monomer which can be polymerized by free-radical polymerization. These synthetic resin dispersions are used as binders in electrodeposition coating baths.
    Type: Grant
    Filed: April 23, 1994
    Date of Patent: October 15, 1996
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Michael Hoenel, Achim Voelker, Gerd Walz, Peter Ziegler