Abstract: The present invention relates to a taste-masked pharmaceutical composition. In particular the invention relates to suspensions of microcapsules taste-masked as a function of a polymer coating and the pH of a suspending medium. Surprisingly, a polymer considered permeable maintains taste masking in this media whereas a polymer considered impervious by the industry does not. There is provided a taste masked oral pharmaceutical composition including: a pharmaceutically active ingredient having a pH-dependent solubility; a polymer encapsulating said pharmaceutically active ingredient, said polymer having a quaternary ammonium functionality; a suspending medium for suspending the encapsulated pharmaceutically active ingredient, said medium adjusted to a predetermined pH at which the pharmaceutically active ingredient remains substantially insoluble; and wherein the pharmaceutically active ingredient is taste masked by the combination of the polymer and suspending medium.

Abstract: The present invention provides a method for producing a material dispersed with ultraviolet shielding fine particles, characterized by subjecting a starting material liquid mixture comprising particles comprising one or more inorganic substances having shielding abilities against ultraviolet light, one or more silicone dispersants selected from modified silicones and reactive silicones, and a silicone oil to a mill treatment and/or a high-pressure dispersion treatment; and ultraviolet shielding fine particles or a material dispersed therewith, characterized by being produced by the above method. Also, the present invention provides a method of producing a powdery product of ultraviolet shielding fine particles, characterized by drying the material dispersed with ultraviolet shielding fine particles obtainable by the above method.

Abstract: A heat sink with a multi-layer dispersion space is directly molded to form an upper and a lower flowing layer. A twin fan design is incorporated into the main body of the heat whereby a pair of centered circular recesses respectively formed for the reception of the cooling fans in the main body of the heat sink. In addition, fan supporters are fixed within the respective circular recesses in order to anchor said cooling fans to the main body of the heat sink; wherein each fan supporter comprises a stopping plate for diverting flow from the lower flowing layer tangentially from the respective fan recess.

Abstract: An artificial operon comprising genes encoding each of a trigger factor, GroEL and GroES, an expression plasmid carrying the operon, an expression plasmid carrying a gene encoding the trigger factor, a cotransformant harboring an expression vector for a foreign protein and any one of the expression plasmids, and a method for producing a foreign protein comprising expressing a foreign protein by the use of the cotransformant, which are capable of expressing a foreign protein in a solubilized form and in a state of having a correct conformation.

Abstract: Methods for the preparation of (2S,3S)-1,5-benzothiazepine derivatives of the formula (II) and isomers thereof, and for the preparation of (2R,3R)-1,5-benzothiazepine derivatives of the formula (III) and isomers thereof, wherein ring A and ring B are independently a substituted or unsubstituted benzene ring, and R2 is a 2-(dimethylamino)ethyl group or a group of the formula: or a pharmaceutically acceptable salt thereof.

Abstract: A negative angular forming die having a lower die for supporting a workpiece. An upper die is lowered with respect to the lower die to abut against the workpiece for forming the workpiece. A columnar body is rotatably mounted on the lower die, and a groove is formed in the columnar body in the axial direction of the lower die. A slide cam is supported on the upper die and is opposed to the columnar body. An automatic returning tool is provided on the lower die for rotating and retracting the columnar body to a position at which the workpiece can be taken out from the lower die after the forming process is completed. The workpiece is placed on the supporting portion of the lower die with the columnar body being turned, and the slide cam is slid to form the workpiece by an entering forming portion of the columnar body. The columnar body is turned and retracted by the automatic returning tool after forming so that the formed workpiece can be taken out from the lower die.

Abstract: There is provided a process for producing an aerogel which comprises lowering a pH of a water glass solution to obtain a sol, gelling the sol to obtain a hydrogel, replacing water in the gel with an organic solvent, reacting the gel with a hydrophobilizing agent having hydrophobic groups as well as functional groups reactive with silanol groups in liquid phase, followed by supercritically drying; or hydrophobilizing and supercritically drying the resultant gel at the same time. Preferably, the hydrogel is prepared by ion exchanging alkali metals in the water glass solution using an ion exchange resin to obtain a sol which is subjected to suspension polymerization.

Abstract: A method for fabricating a non-volatile memory cell for a substrate includes the following steps: forming an isolation structure to define an active region on the substrate; forming a channel oxide layer on the active region; forming a conducting layer and a silicon nitride layer over the substrate; defining the polysilicon layer and the silicon nitride layer to form a floating gate on the active region and to form an opening exposing a portion of the isolation structure; conformally forming an etching protection layer which extends from the isolation structure inside the opening up to the silicon nitride layer; forming an oxide layer over the substrate; planarizing the oxide layer to the surface of the silicon nitride layer so that the remainder of the oxide layer is left within the opening; removing the silicon nitride layer; forming conducting spacers on the sidewalls of the remainder of the oxide layer; removing the remainder of the TEOS oxide layer; conformally forming an ONO layer; forming a controlling

Abstract: An assembly enabling detachable fitting of a pair of auxiliary lenses to a pair of primary spectacles; the assembly including a pair of projections on a primary spectacle frame each having a recess or opening which each receive a corresponding projection on an auxiliary frame which holds the pair of auxiliary lenses. The arrangement is such that each projection on the auxiliary frame positively engages an opening on a corresponding projection on the primary spectacle frame.

Abstract: The invention relates to novel pyridocarbazole derivatives having highly selective action in inhibiting cyclic GMP-phosphodiesterase (hereinafter abbreviated as cGMP-PDE), processes for producing such derivatives, agents containing at least one of such derivatives as an active ingredient for preventing and/or treating pulmonary hypertension, ischemic heart diseases or diseases against which the cGMP-PDE inhibitory action is effective, and intermediates useful for the production of pyridocarbazole derivatives.

Abstract: An apparatus and method substantially reduce moments of a steering axle while substantially increasing clearance between the steering axle and a ground surface and increasing strength of the axle. The method and apparatus also include a reversible high ground clearance steering axle having stops at different relative locations which facilitate mounting of the steering axle on more than one type of vehicle.

Abstract: A combination of a capsule for incorporating a radioactive source to be applied in brachytherapy and a guidewire, in which the capsule is attached to the guidewire via an adapter, and the adapter comprises a cable or thread with a flexibility greater than that of the guidewire

Abstract: A curable resin composition contains (A) a curable resin and (B) a ketimine structure-bearing organosilicon compound obtained by reacting an amino-functional alkoxysilane with a monocarbonyl compound, the organosilicon compound having a monomer purity of 50-95% and an amino group blockage of at least 90%. The composition has good shelf stability and tight adhesion and is useful as an adhesive.

Abstract: A run-flat tire comprises a carcass composed of an inner ply and an outer ply each made of organic fiber cords, a belt disposed radially outside the carcass in the tread portion, and three sidewall reinforcing rubber layers disposed in each sidewall portion. The inner and outer carcass plies are turned up around the bead cores from the inside to the outside of the tire, and the turnup portions of the inner carcass ply extends into between the belt and the carcass so that the radially outer end thereof is secured therebetween. The sidewall reinforcing layers include: an inside layer disposed axially inside the main portion of the inner ply; a middle layer disposed between the main portion of the inner ply and the main portion of the outer ply; and an outside layer disposed axially outside the main portion of the outer ply. At least one of the sidewall reinforcing rubber layers has a radially outer end located beneath the belt.

Abstract: A ferroelectric thin film includes: a bismuth oxide polycrystal thin film constituting a buffer layer, and a bismuth-based layered compound thin film represented by the formula: Bi2Am-1BmO3m+3 wherein A is an atom selected from the group consisting of Na, K, Pb, Ca, Sr, Ba and Bi; B is an atom selected from the group consisting of Fe, Ti, Nb, Ta, W and Mo; and m is an integer of 1 or more. The bismuth oxide polycrystal thin film and the bismuth-based layered compound thin film are formed into a single-phase.

Abstract: In the case of a print order where the content of an order regarding print output is provided from a user to a laboratory in a digital form, necessity of printing or the like can be decided at the time of image data acquisition and the image data sets can be classified and stored before they are provided to the laboratory. Furthermore, an order of prints wherein a plurality of image data sets are used, such as printing of a composed photograph, can be placed easily. A portion of the order information, such as necessity of printing, is added to image data as tag information. The reset of the order information is described as order information in an order file. The image data to be printed is specified by image information in the order file, and an addition to flag showing that the tag information needs to be referred to is set to ON.

Abstract: The invention provides a fiberboard, as well as its manufacturing method, which comprises lignocellulose long fibers with a fiber length 50 mm or more and resin. The fiberboard of the invention has high mechanical strength and superior dimensional stability. Since lignocellulose-base materials of long fibers are utilized, the fiberboard can save the consumption of precious wood resources.

Abstract: An external preparation for topical administration which aims at inhibiting rejection reactions at organ or bone marrow transplantation or treating autoimmune diseases or allergic diseases and contains as the active ingredient 2-amino-2-(2-(4-octylphenyl)ethyl)propane-1,3-diol or a pharmaceutically acceptable acid addition salt thereof.

Abstract: The present invention provides a detergent composition which is excellent in enzyme stability and exhibits excellent detergency particularly to protein-related dirt of socks and other items even under laundering conditions at a lower temperature. That is, the present invention provides a detergent composition comprising specific proportions of (a) an anionic surfactant, (b) a chlorine scavenger, (c) a protease whose &agr;-keratin-hydrolyzing activity at 10° C. is not less than 0.09×10−3 &mgr;g/mPU·min and (d) a protease whose &agr;-keratin-hydrolyzing activity at 10° C. is less than 0.09×10−3 &mgr;g/mPU·min.

Abstract: Disclosed is a reel for winding photosensitive film (6) which stabilizes the winding shape of the film and minimizes the deformation of a photosensitive layer caused by the winding tension. The winding reel is easily carried and stored, and has a sufficient strength to stand against the winding tension of the wound photosensitive film. The user can check the amount of the wound photosensitive film. The winding reel has a cylindrical reel member (10) for winding the photosensitive film around a circumference thereof with a predetermined tension, and flange members (20, 30) detachably coupled to both sides of the reel member. The flange members (20, 30) have inner surfaces which are disposed in opposition to each other and are closed to both edges of the photosensitive film wound around the reel member. By the winding reel, it is possible to wind the photosensitive film around the reel member (10) with a proper tension.