Patents Represented by Attorney, Agent or Law Firm Birch, Stewart, Solasch & Birch, LLP
  • Extending the lifetime of anticoagulant oligodeoxynucleotide aptamers in blood
    Patent number: 6780850
    Abstract: The present invention is a complex of a polynucleotide having a property of specifically binding to a target protein together with a protein that stabilizes the polynucleotide from degradation and from clearance from the circulation in vivo. Methods for diagnostic imaging and therapeutic uses of the complex are disclosed.
    Type: Grant
    Filed: June 22, 2000
    Date of Patent: August 24, 2004
    Assignee: TRIUMF
    Inventors: Alfred H. Dougan, Jeffrey I. Weitz