Patents Represented by Attorney, Agent or Law Firm Birgit Millauer
  • Conjugate consisting of an active substance and a non-exogenous native protein
    Patent number: 6812209
    Abstract: This invention relates to a conjugate which consists of an active substance and a native protein which is not regarded as exogenous and distinguish itself in that an intracellulary cleavable linker is present between the active substance and the protein. In addition, this invention concerns a process for the preparation of such a conjugate and its use.
    Type: Grant
    Filed: August 16, 2000
    Date of Patent: November 2, 2004
    Assignee: Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts
    Inventors: Hansjörg Sinn, Hans-Hermann Schrenk, Wolfgang Maier-Borst, Gerd Stehle, Andreas Wunder, Dirk Hoff-Biederbeck, Dieter Ludwig Heene
  • Antibodies active against a fusion polypeptide comprising a histidine portion
    Patent number: 6790940
    Abstract: The present invention relates to an antibody active against a fusion polypeptide comprising a histidine portion, a process for the preparation thereof and its use.
    Type: Grant
    Filed: February 9, 1998
    Date of Patent: September 14, 2004
    Assignee: Deutsches Krebsforschungszentrum Stiftung des offentlichen Rechts
    Inventors: Hanswalter Zentgraf, Claudia Tessmer, Iris Velhagen, Susanne Schwinn, Manfred Frey
  • Encapsulated cells containing an amplified expression vector as a drug delivery device
    Patent number: 6713293
    Abstract: The present invention provides a drug delivery device comprising encapsulated cells that contain multiple copies of an expression cassette. The drug delivery device of the present invention is useful to supply an animal, including a human, with a therapeutically desirable molecule, including physiological activities lacking in disease conditions or antagonist against conditions in an animal, especially a human.
    Type: Grant
    Filed: February 8, 1999
    Date of Patent: March 30, 2004
    Inventors: Friedrich Grummt, Birgitta Sauer, Martha Müller