Patents Represented by Attorney Bowdy and Neimark, PLLC
  • Patent number: 7517856
    Abstract: The present invention provides bioconjugates comprising a sulfated polysaccharide such as alginate sulfate and hyaluronan sulfate and at least one bioactive polypeptide capable of binding a sulfate group of said sulfated polysaccharide. The bioactive polypeptide can be a heparin-binding polypeptide and/or a positively-charged polypeptide. Also, provided are delivery systems and methods for sustained release of said bioactive polypeptide(s) using said bioconjugates.
    Type: Grant
    Filed: October 11, 2005
    Date of Patent: April 14, 2009
    Assignee: Ben-Gurion University of the Negev Research and Development Authority
    Inventors: Smadar Cohen, Inbar Freeman