Patents Represented by Attorney, Agent or Law Firm Braman & Rogalskyj, LLP
  • Patent number: 5877155
    Abstract: The present invention is directed to an isolated peptide that functionally mimics a binding site for a monoclonal antibody, the monoclonal antibody recognizing an epitope within the human platelet glycoprotein Ib/IX complex. This peptide is called a mimotope. The invention also provides an isolated molecule capable of binding to the peptide, or the mimotope, which molecule can be an antibody, a second peptide, a carbohydrate, a DNA molecule, an RNA molecule, or other naturally or chemically synthesized molecules. This isolated molecule is called an anti-mimotope. Mimotopes mimicking the binding site for monoclonal antibody C-34 and SZ-2, as well as anti-mimotopes to the C-34 mimotopes, are specifically provided.
    Type: Grant
    Filed: November 13, 1995
    Date of Patent: March 2, 1999
    Assignee: The Research Foundation of State University of New York
    Inventors: Jonathan L. Miller, Vicki A. Lyle