Patents Represented by Attorney, Agent or Law Firm Brian Buckwalter
  • Benzocycloalkylenylamine derivatives as muscarinic receptor antagonists
    Patent number: 6645958
    Abstract: This invention relates to compounds which are generally muscarinic M2/M3 receptor antagonists and which are represented by Formula I: wherein X, Y, and Z are O, S, or NR4, and the other substituents are as defined in the specification; and prodrugs, individual isomers, racemic or non-racemic mixtures of isomers, and pharmaceutically acceptable salts or solvates thereof. The invention further relates to pharmaceutical compositions containing such compounds and methods for their use as therapeutic agents.
    Type: Grant
    Filed: November 6, 2002
    Date of Patent: November 11, 2003
    Assignee: Syntex (U.S.A.) LLC
    Inventors: Robert James Weikert, Ann Marie Madera, Russell Stephen Stabler
  • Amino-tetralin derivatives as muscarinic receptor antagonists
    Patent number: 6635658
    Abstract: This invention relates to compounds which are generally muscarinic M2/M3 receptor antagonists and which are represented by Formula I: wherein R1, R2, R3 and R4 are as defined in the specification, or individual isomers, racemic or non-racemic mixtures of isomers, or acceptable salts or solvates thereof. The invention further relates to pharmaceutical compositions containing such compounds and methods for their use and preparation as therapeutic drugs.
    Type: Grant
    Filed: December 2, 2002
    Date of Patent: October 21, 2003
    Assignee: Syntex (U.S.A.) LLC
    Inventors: Ann Marie Madera, Robert James Weikert
  • 4-piperidinyl alkyl amine derivatives as muscarinic receptor antagonists
    Patent number: 6627644
    Abstract: This invention relates to compounds which are generally muscarinic receptor antagonists and which are represented by Formula I: wherein p, R1, R2, R3 and A are as defined in the specification, or individual isomers, racemic or non-racemic mixtures of isomers, or acceptable salts or solvates thereof. The invention further relates to pharmaceutical compositions containing such compounds and methods for their use and preparation as therapeutic drugs.
    Type: Grant
    Filed: December 2, 2002
    Date of Patent: September 30, 2003
    Assignee: Syntex (U.S.A.) LLC
    Inventors: Christine E. Brotherton-Pleiss, Ann Marie Madera, Robert James Weikert