Abstract: A multilayer brazeable metallization structure for diamond components is described. The brazeable metallization finds particular application for the attachment of diamond components such as heat spreaders in electronic packages that incorporate high power semiconductor devices. In the present invention, a diamond component is provided with a multilayer coating of metals including a first layer of chromium for adhesion, a second barrier layer of a refractory metal for a barrier that may be alloyed with chromium, and a top layer of copper, silver or gold for wetting. The refractory metals for the second layer include tungsten, molybdenum, tantalum and niobium. Tungsten or tungsten-chromium alloy is preferred as the second layer. This multilayer metallization structure provides a robust interface between diamond and standard brazing alloys which are used to join the diamond to electrical leads or a flange made of metals such as copper-tungsten.

Abstract: The invention relates to an exhaustion agent, which is an aqueous emulsion of polymerized monomers, wherein the monomers contain: (meth)acrylic acid (MAA); alkyl (meth)acrylate, such as methyl (meth)acrylate (MMA); and a substituted or unsubstituted styrene; and having an average particle size of the emulsified particles is less than about 220 nm.

Abstract: Ultrasound application devices and methods of use for sternum healing of a patient includes the steps of positioning an ultrasound application device near a sternum having approximated portions, and applying ultrasound to the approximated portions for promoting healing. The ultrasound application device includes a transducer for generating the ultrasound, and a base for positioning the transducer near to the sternum. A diverging lens may be disposed between the transducer and the sternum for acoustically diverging the ultrasound to flood the sternum with ultrasound. A plurality of transducers may be included in a plurality of recesses of the base along a longitudinal length of the sternum for applying the ultrasound along the longitudinal length of the sternum. A ring may be included to be positioned and secured about the neck of the patient. The ring may be woven as and/or incorporated in a tie.

Abstract: A cast punch and mounting assembly for forming an opening in an orthopedic cast and securing a therapeutic treatment device within the opening adjacent a bone or musculoskeletal injury is provided. The assembly includes a cast punch housing which is fastened to the body surface beneath the cast. The cast punch housing includes a central bore and a guide rod extending outwardly from the central bore. The guide rod extends through the cast. A punch member and a drive member are operably connected to the guide rod and are moveable towards the central bore of the cast punch housing to core an opening in the cast above the central bore. The central bore includes engagement structure to releasably secure a therapeutic treatment device within the central bore of the cast punch housing.

Abstract: The system is used for therapeutically treating injuries using ultrasound. The system includes an ergonomically constructed ultrasonic transducer treatment head module and a main operating unit. The transducer treatment head module is positioned adjacent the area of the injury and excited for a predetermined period of time. The system includes a bathtub insert that envelops a portion of the patient's body, and means on the insert for positioning and holding the treatment head module adjacent positions on the patient's body.

Abstract: The invention relates to apparatus and method for therapeutically treating reflex sympathetic dystrophy using ultra sound. The apparatus includes at least one ergonomically constructed ultrasonic transducer configured to cooperate with a placement module or strip for placement in proximity to pain receptors of the sympathetic nervous system. The apparatus also utilizes a portable, ergonomically constructed main operating unit constructed to fit within a pouch worn by the patient. In operation, at least one ultrasonic transducer positioned in proximity to the pain receptors of the sympathetic nervous system is excited for a predetermined period of time. To ensure that at least one ultrasonic transducer is properly positioned, and to insure compliance with a treatment protocol, a safety interlock is provided to prevent inadvertent excitation of the at least one ultrasonic transducer.

Abstract: Fibrointimal proliferation, neointimal hyperplasia and other vascular lesions or injuries are reduced by ex vivo irradiation of the autologous coronary bypass conduit, especially the saphenous vein, as an adjunct in cardiovascular surgery or other treatment, in anyone of a variety of suitable devices.

Abstract: The present invention is directed to brazing filler metals that can be used in the infiltration brazing of porous matrix materials without the need for a flux. The brazing filler metals contain two different Group II metals and a third metal of Group 9 and 10. A particular brazing filler metal of the invention contains silver, copper, and nickel. The invention is also directed to composite materials formed by infiltration of the brazing material into a porous matrix, and to methods for preparing the composite materials. The invention is further directed to composite articles fabricated from composite materials, including steel bearings or bushings, and to methods of preparing the composite articles.

Abstract: The present invention relates to novel nonpolymeric compounds and compositions that form liquid, high viscosity materials suitable for the delivery of biologically active substances in a controlled fashion, and for use as medical or surgical devices. The materials can optionally be diluted with a solvent to form a material of lower viscosity, rendering the material easy to administer. This solvent may be water insoluble or water soluble, where the water soluble solvent rapidly diffuses or migrates away from the material in vivo, leaving a higher viscosity liquid material.

Abstract: A self-contained ultrasound applicator for therapeutically treating injuries. The self-contained ultrasound applicator comprises a cantilever mounting structure, a cantilever connected to the mounting structure, a main operating unit operably mounted adjacent the cantilever and an ultrasonic transducer positioned adjacent a distal portion of the cantilever for abutment with a treatment site. The self-contained ultrasound applicator includes a means for attaching adjacent a treatment site. The cantilever is configured to urgingly bias the ultrasonic transducer toward a treatment site when mounted adjacent the treatment site.

Abstract: A method and device for treating acute mania or bipolar disorder is disclosed, by transdermal delivery of Li+ at substantially constant rate through the skin via a dermal patch.

Abstract: Compounds such as formula (I) are useful in the treatment of tumor cells and the treatment of cancer.

Abstract: Novel calcium phosphate core particles, methods of making them, and methods of using them as vaccine adjuvants, as cores, as carriers of biologically active material, and as controlled release matrices for biologically active material are disclosed. The core particles may have a surface modifying agent and/or biologically active material, such as antigenic material or natural immunoenhancing factor, polynucleotide material, or therapeutic proteins or peptides, partially coating the particle or impregnated therein. The core particles have a diameter between about 300 nm and about 4000 nm, more particularly between about 300 nm and about 2000 nm, and even more particularly between about 300 nm and about 1000 nm, are substantially spherical in shape, and have a substantially smooth surface.

Abstract: The present invention relates to vitrification of ion exchange resins that have become loaded with hazardous or radioactive wastes, in a way that produces a homogenous and durable waste form and reduces the disposal volume of the resin. The methods of the present invention involve directly adding borosilicate glass formers and an oxidizer to the ion exchange resin and heating the mixture at sufficient temperature to produce homogeneous glass.

Abstract: The apparatus is used for therapeutically treating injuries using ultrasound. The present invention may include a therapeutic ultrasonic composite comprising a transducer and an integrated circuit unit positioned adjacent the transducer. The therapeutic ultrasonic composite also includes signal generation circuitry, housed on the integrated circuit unit, for generating a driving signal for the transducer, and a driving interface between the signal generation circuitry and the transducer. In operation, driving signals generated by the signal generation circuitry are transmitted to the transducer by the interface, thereby driving the transducer for the creation of therapeutic ultrasound.

Abstract: The present invention relates to compositions and methods for treating water to reduce the phosphate level thereof and control the growth therein of algae and other microorganisms by treating the water with an effective amount of a composition containing a lanthanide halide.

Abstract: The present invention relates to a storage device for use with a carrying case, and having an aperture therein adapted to receive a handle or strap of the carrying case. The device may also have attachment devices enabling the device to be carried separate from the carrying case if desired. Side body portions of the device have compartments that are adapted to receive, store, and carry items of various sizes. These compartments may be lined with material to protect or enhance the items contained therein. Optional straps may extend from the bottom edges of the side portions in order to attach and secure the device onto a carrying case.

Abstract: A portable therapeutic device and method of use generate longitudinally propagating ultrasound and shear waves generated by such longitudinally propagating ultrasound to provide effective healing of wounds. A transducer having an operative surface is disposed substantially adjacent to the wound to emit ultrasound to propagate in the direction of the wound to promote healing. Reflections of the ultrasound by bone tissue, by skin layers, or by internally disposed reflective media propagate toward the wound as longitudinal waves, with shear waves generated by the longitudinal waves for the healing of the wound. A focusing element is used for focusing the propagation of the ultrasound at a predetermined angle toward the wound. The operative surface of the transducer may be annularly shaped to encircle the wound to convey the ultrasound and/or reflected ultrasound thereto.

Abstract: The invention relates to methods of vitrifying waste and for lowering the melting point of glass forming systems by including lithia formers in the glass forming composition in significant amounts, typically from about 0.16 wt % to about 11 wt %, based on the total glass forming oxides. The lithia is typically included as a replacement for alkali oxide glass formers that would normally be present in a particular glass forming system. Replacement can occur on a mole percent or weight percent basis, and typically results in a composition wherein lithia forms about 10 wt % to about 100 wt % of the alkali oxide glass formers present in the composition. The present invention also relates to the high lithia glass compositions formed by these methods.

Abstract: The present invention relates to water purification compositions comprising silver and a second material, such as aluminum or zinc metal, to methods of treating or purifying water using this composition.