Abstract: Compounds, compositions, and methods of use as a pharmaceutical, where the compounds have structure (I), where B is --C(.dbd.O)-- or --CH.sub.2 --O--, C is a direct bond or is a diol residue, a hydroxy-substituted carboxylic acid residue, or a dicarboxylic acid residue, and D is a fatty acid residue or a fatty alcohol residue, where the acid residues or alcohol residues for ester linkages with the corresponding alcohols or acids.
Type:
Grant
Filed:
March 3, 1998
Date of Patent:
January 18, 2000
Inventors:
David Frederick Horrobin, Mehar Manku, Austin McMordie, Philip Knowles, Peter Redden, Andrea Pitt